Tag: "inflammatory" at medical news
New anti-inflammatory drug clears Alzheimer's provoking protein from brains of mice
... that people who routinely take NSAIDs for chronic inflammatory
conditions like arthritis are less likely to devel...e anti-inflammatory drugs would reduce the brain's inflammatory
response caused by the amyloid deposits. The unexpected result suggests that increased immune acti...
$2.2 Million herbal cold remedy study underway at U.Va.
...as an effect on viral replication or on the body's inflammatory
response," Turner said. "It may involve a combination of several factors." Echinacea is indigenous to the American Midwest, and was first used for medicinal purposes by Native Americans, according to ethnobotanists. White settlers adopted it as a fol...
Can an aspirin a day keep atherosclerosis at bay?
...earch indicating that atherosclerosis is a chronic inflammatory
disease," said Domenico Pratic, MD, assistant prof...is is associated with increased levels of cellular inflammatory
signals called cytokines. Plaque formation is also associated with increased levels in the aorta of...
UCSD team identifies potential role of CRP in development of antherosclerosis
...modulation of atherosclerosis, as well as in other inflammatory
disease," said Mi-Kyung Chang, M.D., an assistant project scientist and the first author of the paper in PNAS. In the new studies, the UCSD team showed that CRP binds to oxidized LDL through the recognition of phosphocholine, a part of an oxidized mo...
Gene therapy promising for preventing restenosis
...h in the arteries' interior lining and reduced the inflammatory
response two main causes of re-narrowing of newly opened blood vessels, researchers report in today's rapid access issue of Circulation: Journal of the American Heart Association. The process that opens blocked blood vessels either inflating a tiny...
Chili peppers and inflammation: Researchers unravel mechanism of pain sensitivity
...to understand why patients with arthritis or other inflammatory
conditions are likely to have increased pain and sensitivity to heat," says Woolf. He and his research team were surprised to find that the activation of p38 can cause a twenty-fold increase in the amount of TRPV1 protein in the skin but not in the ...
'Glutaid' on the horizon? Study may someday spell relief for people on gluten-free diets
...nd the resulting product was a potent stimulant of inflammatory
T cells isolated from small intestines of celiacs. Although other peptides capable of triggering celiac-specific T cells have been identified from gluten, they are structurally related to the peptide identified in this study. Thus, Khosla and his co...
Non-traditional tests may be dynamic duo in predicting heart problems
...sclerosis, while CRP suggests that plaque contains inflammatory
factors that make it more prone to rupture and block blood vessels. "Together they can gauge the presence, the amount and the stability of artery-clogging plaque," says Detrano. Recent research has shown elevated CRP levels impart increased risk of...
Antioxidant reduces brain damage in stroke model
... showed that the antioxidant significantly altered inflammatory
gene expression in tissue....
Smoking found to be an important risk factor for colorectal polyps
...mass index, weekly exercise habits, and history of inflammatory
bowel disease. "Perhaps an even more important finding is that a much larger proportion of the smokers had more than two polyps, had a polyp larger than 1 centimeter, or had a polyp with a greater potential for malignancy. These differences had high...
Glucocorticoid use increases risk of spinal fractures
...glucocorticoids to treat a variety of allergic and inflammatory
diseases. Long-term (=3 months) use for chronic diseases is associated with a serious complication called glucocorticoid-induced osteoporosis (GIO). "Osteoporotic fractures are typically associated with postmenopausal osteoporosis, but up to one h...
$2 per dose vs. $1500 per dose: One doctor develops new therapy for macular degeneration
...inolone, a drug normally used for the treatment of inflammatory
conditions such as arthritis, into the eye. Visudyne infusion is given to a patient followed by a treatment with a cold laser that does not injure the macular tissue.The combination of the drug and the cold laser results in an activated version of th...
Inflammation may increase stroke risk in men with hypertension
...ood pressure and normal ISP levels. Moreover, the inflammatory
proteins predicted stroke risk for 10 or more years. "It is our conclusion that high ISP levels are associated with elevated blood pressure," says lead author Gunnar Engstrm, M.D., Ph.D., of Malmo University Hospital in Malmo, Sweden. "These protei...
Chronic stress can interfere with normal function of the immune system
...ay researchers, possibly altering the course of an inflammatory
disease. This finding is reported on in the Novemb...s that normally are responsible for terminating an inflammatory
response following infection and/or injury, according to researchers Gregory E. Miller, Ph.D., of Wa...
Herpes simplex virus-2 may increase risk of cervical cancer
...t HSV-2 and other infectious agents may trigger an inflammatory
response, which generates DNA-damaging free radicals, which are thought to play important roles in the initiation and the progression of cancers. "Further studies of the natural history of HPV infection in relation to infection with other cervical...
Cholesterol drug could lead to new therapy for multiple sclerosis
...helper (Th) cell, or CD4+ T cell, orchestrates an inflammatory
attack against the brain's nervous tissue. The pri...ermined that atorvastatin acts by interrupting the inflammatory
process. In the mouse models, Youssef, working closely with Zamvil, determined the drug's impact on ...
New treatment strategy for Crohn's disease shows early promise
...with moderate to severe forms of the debilitating, inflammatory
gastrointestinal disorder. The results are reported in the Nov. 9, 2002 issue of The Lancet by investigators at Washington University School of Medicine in St. Louis. Crohn's disease is a chronic, lifelong condition, which affects about half a milli...
Sepsis vaccine proves protective in preliminary studies at The Scripps Research Institute
... Sepsis, also known as septic shock and systemic inflammatory
response syndrome, is characterized by shock to on...acrophages respond by producing a lethal amount of inflammatory
chemicals. One of these chemicals is called tumor necrosis factor alpha (TNF-alpha). The prognosis ...
Trial opens new possibilities for improving survival with a novel heart attack drug
...h a stimulus. The end result of this cascade is an inflammatory
response that destroys foreign substances. Pexeliz...f the complement cascade to decrease the amount of inflammatory
damage when blood flow is restored and thereby improve patient outcomes," Grange said. "This drug is...
Protecting babies from RSV could reduce the chances of wheeze and asthma during childhood
...ing produced more severe weight loss and increased inflammatory
cell recruitment to the lungs (including T helper 2 cells, neutrophils and eosinophils) during re-infection whereas delayed priming led to enhanced interferon gamma production and less severe disease during re-infection. The research was made possib...
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