Auditory screening for newborns can be successful, UT Southwestern researchers report
... all neonates was begun in 1999. Babies who do not initially pass are rescreened by technicians before being discharged from the hospital. Parents of babies who still show signs of impairment are instructed to bring them back to Parkland as outpatients to be retested 10 to 12 days after discharge. Only those w...Case definition for polyneuropathy developed to standardize research
...ilitate clinical research. The three organizations initially intended to develop a practice guideline about treatment for polyneuropathy, a noninflammatory nerve disease. The definition of polyneuropathy was inconsistent in available studies, making it impossible to compare the studies and make recommendations...Study shows drugs such as Vioxx and Celebrex were widely over-used long before recent problems
...vative therapies to the settings in which they are initially targeted and maximally cost-effective." Carolanne Dai of the University of Chicago was the lead author of the paper. The research was supported by the MacLean Center for Clinical Medical Ethics at the University of Chicago, the National Institute of...Mobile surgical units prevent delays in treating wounded combat patients in Iraq
...te care of life- or limb-threatening injuries were initially taken into the FRSS. For Marines, the median [half-way] time from wounding to arrival at the FRSS was one hour, with a range of 15 minutes to 40 hours. Time of wounding was known in 35 of the 60 Iraqi patients, and they had a median time from woundin...Penn researchers add more evidence to demonstrate role of COX inhibitors in heart-disease risk
...f heart attack and stroke. This proposal was based initially on his studies of how celecoxib (Celebrex) and rofeocoxib (Vioxx) worked in human volunteers. The first unequivocal evidence of this risk emerged with the Merck-sponsored APPROVe study of Vioxx, leading to withdrawal of the drug in September 2004. Ev...Future of clinical medicine research is at risk, warns professor
...in the airways. By applying proteomic techniques, initially to washings from the lung airways and latterly to induced sputum, highly specific proteins relating to the disease and the inflammation have been identified. The same techniques have shown similarly promising results in other lung diseases including...New treatment guidelines for pregnant women with asthma
...ly, asthma improved in 23 percent of the women who initially had moderate or severe asthma. "We cannot predict who will worsen during pregnancy, so the new guidelines recommend that pregnant patients with persistent asthma have their asthma checked at least monthly by a healthcare provider," explained Mitche...Workers with carpal tunnel find relief with night-time splinting
...ent in hand/wrist discomfort, and participants who initially reported higher levels of discomfort at the start of the study saw the greatest improvements with splint use. Additionally, 10 percent of the participants in this group continued to wear the splint at night beyond the initial six-week trial. Prior to...USC researchers find evidence that progesterone signaling influences ovarian cancer risk
...he Journal of the National Cancer Institute , was initially supposed to be a more in-depth look at one particular version-or allele-of the progesterone receptor gene (PGR). The PROGINS allele, says Celeste Leigh Pearce, a preventive medicine researcher from the USC/Norris Comprehensive Cancer Center and the p...Rare type of pneumonia occurring at higher than normal rate among US troops in Iraq
...e requiring mechanical ventilation. Clinicians may initially confuse AEP with severe community-acquired pneumonia, acute respiratory distress syndrome (ARDS), or both. Severe pneumonia was previously reported from March through August 2003 among 19 U.S. military personnel who were deployed in support of Operat...Potentially fatal toxicities occur with off-label use of cancer drugs
...e-drug treatment (5 percent). Thalidomide, banned initially in 1962, has had a remarkable resurgence since 1998 for cancer, although its formal FDA approval is as a treatment of skin complication of the rare illness, leprosy. "Given the current controversies about the FDA and pharmaceutical safety, our findi...ZYVOX(R) demonstrates high success rate for patients who develop MRSA surgical site infections
...) in the vancomycin group. About ZYVOX ZYVOX was initially approved in the United States in April 2000 for the treatment of complicated skin and skin structure infections and nosocomial pneumonia, including those caused by MRSA. In December 2002, ZYVOX was approved for use in pediatric patients and subseque...Study finds women hesitant to take tamoxifen as preventive measure
...arly all of whom had opted against treatment after initially choosing the treatment. A total of 51 percent chose to either take tamoxifen or to enroll in the STAR trial, 35 percent declined treatment and 14 percent remained undecided. Researchers assessed the influence of health-related variables on participan...First blood test to diagnose paralyzing, blinding disease
... However, the significance of the antibody was not initially appreciated. Based on a study of one group of patients with clinically recognized NMO, the researchers discovered that this "unclassified" antibody was common among these patients and therefore useful as a diagnostic biomarker for NMO. The results s...M. D. Anderson researchers discover key protein in psoriasis
...opment of psoriasis. The transplanted skin did not initially develop psoriasis lesions. However, when the scientists injected activated T cells into the skin grafts on T cell-free mice, the mice then developed psoriasis following mild injury. "This experiment showed it is necessary to have both activated STAT3...Voluntary health organizations, publishers announce major information initiative
...f the American Cancer Society. patientINFORM will initially focus on three diseases, cancer, diabetes, and heart disease, through the participation of three voluntary health organizations: The American Cancer Society (ACS), the American Diabetes Association (ADA), and American Heart Association (AHA); more th...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
...gy, included among its treatment options for women initially started on tamoxifen a switch to an aromatase inhibitor based on data from the AROMASIN study, IES. Professor Charles Coombes, Director of the Cancer Research UK Laboratories at Imperial College London, Hammersmith and Charing Cross Hospitals presen...Long-term benefits for newly diagnosed patients with CML receiving first-line therapy with imatinib
...d after 1 year of treatment, instead of 2 years as initially required, and to enable patients in the IFN + ara-C arm to cross over to imatinib at any time, if desired....Farnesyl transferase inhibitor can help patients at high-risk for developing AML
...n of cancer-promoting proteins. While the drug was initially believed to act primarily on the ras gene, which is mutated in about 25 percent of MDS patients, recent studies including this one demonstrate that patients whose ras gene is normal can benefit, Kurzrock says. "It has become apparent that Zarnestra r...Nerve damage from alcoholism reversed after liver transplantation
... but did improve following the transplant. "We initially considered the peripheral neuropathy in our patient to be a contraindication to OLT [orthotopic liver transplantation] due to its significant impact on his quality of life and the uncertainty about its prognosis following transplantation," the author...