AstraZeneca submits regulatory application in Europe for use of Atacand(R) in heart failure
...blood pressure more effectively than losartan, the initially introduced AT1-receptor blocker 5,6,7,8. Recent clinical outcome studies with Atacand, SCOPE and CHARM, have demonstrated the clinical value of the medicine in hypertension and heart failure, strengthening the position of Atacand as the premier AT1-...SOS Rx: National medication safety group organized
...d to help make those changes a reality." SOS Rx is initially funded by an unrestricted educational grant from founding sponsor Express Scripts. "Express Scripts' mission is to make the use of prescription drugs safer, as well as affordable, so we're very pleased to collaborate with the National Consumers Leagu...UCLA research explores biology of fear
...e forms of active learning. A unique pairing of an initially neutral conditional stimulus with an unpleasant un...exposures to the conditional stimulus alone, might initially appear to be a passive decay or erasure of this association, many studies indicate that extinction i...Human studies show feasibility of brain-machine interfaces
...ttached to the surface of the cerebral cortex. "We initially used subcortical electrodes, because they are more stable because they are buried deeper," said Turner. Also, he said, the deeper regions present other advantages. "The way the brain works, all the signals for motor control are filtered through these...Infants with fevers receive as good care when physicians rely on judgment than clinical guidelines
...s, performed laboratory testing in 75 percent, and initially treated 57 percent with antibiotics," the authors report. "The majority (64 percent) were treated exclusively outside of the hospital. [Bacteria in the blood] was detected in 1.8 percent of infants (2.4 percent of those tested) and bacterial menin...UCSF study: Pediatrician's judgment often better than clinical guidelines for treating infant fever
...s, performed laboratory testing in 75 percent, and initially treated 57 percent with antibiotics, the researchers report. The majority (64 percent) were treated exclusively outside of the hospital. Bacteria in the blood was detected in 1.8 percent of infants (2.4 percent of those tested) and bacterial meningit...'White coat hypertension' common among sleep apnea patients
... Results showed that in patients with sleep apnea initially diagnosed with hypertension, 30 patients were confirmed to have sustained hypertension, while the remaining 15 patients had normal blood pressure readings. All other patients presented normal blood pressure readings. Further analysis revealed that ...Those infected with HIV may benefit from infection with another virus, says Jefferson virologist
...r. Pomerantz should know. He was skeptical when he initially encountered several small, unconfirmed studies a few years ago showing that HIV-infected individuals appeared to do better when they also were infected with GBV-C. Viruses such as Epstein-Barr virus and herpes simplex 2, for example, are supposed to ...'Care managers' help depressed elderly reduce suicidal thoughts
... months, about 70 percent of intervention patients initially plagued by suicidal thoughts were free of them, compared to about 44 percent of "usual care" patients. Although the intervention didn't lift depression symptoms in patients with minor depression any more than usual care, it did significantly decrease...Study shows drug can heal, reduce recurrence of fistulas in Crohn's disease
...ps patients were assigned. Among participants who initially showed a response to infliximab, fistulas recurred much less frequently among those receiving continuing treatment than in the placebo group. At the end of the 54-week study, almost half those receiving infliximab still showed some response, with mo...Study shows women's medication use higher than expected
...s uncovered additional medications patients didn't initially report. They also discovered that while a patient may report that she's taking a medication during the first visit's interview, she failed to mention it on subsequent visits without prompting. The interviews were conducted during a 42-month period. D...Risk of infection higher for piercing ear cartilage than lobe piercing
...onfirmed cases were 10 to 19 years old. Most were initially treated with antibiotics ineffective against Pseudomonas. Four were hospitalized, four underwent incision and drainage surgeries (1 as an outpatient), and several were cosmetically deformed. Upper ear cartilage piercing was more likely to result in...Study provides new insights about brain organization
...estigator. "In this view, information is processed initially on a sense-by-sense basis and doesn't come together until much later. However, this view has recently been challenged by studies showing that processing in the visual area of the brain, for example, can be influenced by hearing and touch." Wallace a...New flu vaccine provides insight into immunity development
...rst description of what became the FluMist vaccine initially was published in 1967, he noted. When such a long development period is involved, Greenberg noted, evaluation criteria can change. In the case of FluMist, the regulatory agencies increased the number of people it considered sufficient to demonstrate ...Storing too much iron may put healthy women at increased risk for type 2 diabetes
... authors note that iron excess seems to contribute initially to insulin resistance and subsequently to decreased insulin secretion. Rui Jiang, M.D., Dr.P.H., from the Harvard School of Public Health, Boston, and colleagues, evaluated biomarkers reflecting iron stores, including plasma ferritin (an iron-protei...Patients needing dialysis prefer 'peritoneal' method rather than hemodialysis
...outcomes, from October 1995 to June 1998. Of those initially enrolled, 656 (89 percent) returned a satisfaction questionnaire after an average of 7 weeks of dialysis. Information collected included 3 overall ratings and 20 items rating specific aspects of dialysis care. The researchers found that patients r...Blood-diverting catheter holds promise for stroke treatment
... said. A large number of cells in the stroke area initially have the potential to recover if their blood supply is restored. In theory, increasing the volume of blood to these damaged brain cells should preserve some of them even more than three hours after a stroke onset. Ischemic stroke patients who arriv...Unsafe injections rejected as major source of HIV infection in Africa
... well with HIV incidence, that individuals who are initially HIV-negative but at a later date are found to be HIV-positive do not have substantially different histories of injections than those who did not become HIV-positive, that association is not the same as causation, and that high rates of other sexually...New technique for opening blocked carotid arteries significantly lowers complication risk
...ner. Hanel said they began using the new technique initially in patients who were not good candidates for a first carotid endarterectomy, such as persons who have had other neck surgeries, additional health complications or a second blocked carotid artery. During carotid endarterectomy, the artery is clamped...Does the sleeping brain 'wake up' if only just a little with every snore?
...Altarum. Despite the small number of children initially tested, the strength of that correlation did show some promise as a predictor of sleepiness and reduced attention. The researchers are now studying more children. Confirmation of their initial findings could help to answer questions about how slee...