'Bathtub' Equation Aids Diabetes Research
...riggers the immune system to attack cellsthat make insulin in auto-immune diabetes. Another will focus on how sugarregulates the death of cells. Research will also look at the effectiveness of two new pharmaceuticalagents, one that may improve the function of the insulin-producing betacells and another that ...Tighter Chemical Binding = Better Meds
...aldrugs that can regulate the natural synthesis of insulin for diabetics ina gene therapy approach involving implanted cells. Vast Increases in Computer Speed Vast increases in computer speed in recent years make it possibleto perform complex computations of chemical processes in minutes insteadof days, sa......e theability of the patients' muscle to respond to insulin and take up glucose." The findings are reported in the March 26 issue of The New EnglandJournal of Medicine, published by the Massachusetts Medical Society. The studyitself was conducted in Yale's federally supported General Clinical Researc...Compound In Meat Prevents Diabetes, Study Suggests
... diabetes is caused by the body's inability to use insulin well, which causes a buildup of sugar in the blood. If left untreated, Type II diabetes can result in kidney problems, amputation of limbs, blindness, coronary heart disease or strokes. The research on CLA's ability to control Type II diabetes was pu...Polish Dumpling-Like Particle Has Potential In Drug Delivery
... assemble and behave much the way proteins such as insulin do. With insulin, which our pancreas secrete to regulate our blood sugar rates, there are two linear polymer chains of amino acids -- the chemical units that are the building blocks of proteins. The linear chains self-assemble into a three-dimensio...Effective Obesity Treatment Likely To Require Targeting Of Multiple Weight Control Systems
...by reducing calorie intake. When calories are cut, insulin and leptin levelsdecrease, and hormones secreted by the adrenal cortex (glucocoricoid or GChormones) increase -- a combination that activates nerve pathways that stimulateappetite and promote weight gain, while at the same time inhibiting pathwaystha...Injecting Drugs With Sound Waves
...dwaves in place of needles to inject drugs such as insulin and interferondirectly through the skin (3aBV3). Using this technique, the Ekos Corporationin Bothell, Washington (contact Tom Keenan or Joe Eichinger, 425-482-1108) isdeveloping an acoustically based insulin-delivery system for people withdiabetes....Alzheimers Disease Could Soon Be Treated With Nose Drops
...results held true when theresearchers administered insulin growth factor 1, a possible treatment forstroke, in nose drops. Frey's team will report on its findings at a meeting of the AmericanAssociation of Pharmaceutical Scientists in San Francisco in November. The nose,they say, could deliver drugs ...6,000 Pharmaceutical Scientists Convene November 15-19 In San Francisco
... sufferers must receive daily insulin injections to avoid serious, often deadly complica...adian scientist has developed and patented an oral insulin medication that's now set for human trials with the Health Protection Branch (t...World's Premier Pharmaceutical Scientists Share Latest R&D Findings
... Millions of diabetes sufferers must receive daily insulin injections to avoid serious, often deadly complica...adian scientist has developed and patented an oral insulin medication that's now set for human trials with the Health Protection Branch (the Canadian equivalen...Encapsulating Insulin-Producing Cells For Possible Diabetes Therapy
...eseislets are "little endocrine organs" that "make insulin and multiple hormones inaddition to insulin," said... permeable tosmall molecular weight materials like insulin or glucose or oxygen or othernutrients." The islet-enclosing microcapsules are made of hyrog...Discarded Treatment For Heart Attacks May Yet Prove To Be A Life-Saver
...acks. Insulin resistance preventscells from using insulin effectively. The trial was not intended to determine GIK's effectiveness in heartattack patients, but to decide whether a larger investigation of the combinationwas warranted. The ECLA group is now organizing a worldwide study and hasrecruit...Fructose Consumption May Accelerate Aging: Skin's Elasticity And Softness May Be Affected
...hat fructose decreases glucose tolerance,increases insulin resistance and speeds up the process of glycation -- areaction of sugar and proteins which contributes to the development of normalaging as well as to some complications of diabetes. Werman's and Levi's tests proved that blood fructose, ch...UNC Researchers Testing First In New Class Of AIDS Drugs
...r simply by injecting it subcutaneously (much like insulin isadministered in diabetes). T-20 was also given either as part of ananti-retroviral drug "cocktail" or as the sole drug. Eron says the new results definitively show that injection can be an alternativeto infusion. Targeted blood levels of T-20 were ...Childhood Obesity, Diabetes And Hyperlipidemia
...o waistcircumference and abnormal serum lipids and insulin in 3000 childrenaged 5-17. Thus, abdominal obesity in children may predict later diabetes andheart disease....Insulin Resistance And Obesity Avoided In Genetically Modified Mice, As Reported In Science
...r it in the cells. This set of steps is called the insulin "signal."People with type I diabetes (the more sev...and early-onset form of thedisease) do not produce insulin at all and must give themselves regular insulininjections. People with type II diabetes do produce i..."Plugs" For Drugs Promise Mightier Medicines
...bloodglucose levels. When diabetic rats were given insulin modified with themolecular "plug," a single injection kept glucose levels at a normal level fortwo days. In contrast, a single injection of unmodified insulinproduced the same effect for only 6-12 hours. The new "plug" is a small organic molecule wid...Slowing Excess Weight Gain In Childhood Appears To Reduce Adult Heart Disease Risk
...n people are in their early 20s, inparticular, the insulin resistance syndrome -- the condition in which insulin isassociated with obesity and the risk for cardiovascular disease. In the study, rates of in...UI Study Suggests Promising Treatment For Diabetic Pregnancies
... tasks of checking their glucose levels and taking insulin severaltimes daily in an effort to ensure their ba...aterialallows small substances such as glucose and insulin to pass freely but preventsthe large molecules and cells of the immune system from interacting with ......is substance could be a welcome alternative to the insulin injections orrigorous lifestyle monitoring that ar...iabetics, either because their bodiesdon't produce insulin (type I diabetes), or because they are resistant to itseffects (type II). An oral drug that could tr...