Tag: "ion" at medical news
2005 Pulp Biology Research Award
...characterizing the mechanosensitivity of potassium ion
channels of human odontoblasts (KCa and TREK-1). T...ssue. Recently, he showed the expression of sodium ion
channels of the neural form (Nav1.2) in odontoblasts and particularly the putative role of the beta ...
Cellular porthole connects odors to brain
...detecting cells use the same chloride porthole, or ion
transporter -- the former to facilitate secretion of digestive juices, and the latter to communicate information about scents to the brain. Although scientists have long known that odor-sensing cells require lots of charged chloride atoms, or ions,...
New math model of heart cell has novel calcium pathway
...heart cells, for instance, many different kinds of ion
channels interact to generate the action potentials that go through the heart and cause a synchronized, normal contraction. In a normal heart, action potentials form very organized waves of activity and contraction. In arrhythmia, though, normal...
Selective coatings create biological sensors from carbon nanotubes
...rs functionalize the surface with ferricyanide, an ion
that is sensitive to hydrogen peroxide. The ion
attaches to the surface through the porous monolayer. When present, hydrogen peroxide will form a c...
Long-sought key to hearing may be found in protein discovery
...d to a nerve signal. Then, the cilia bend back and ion
channels snap shut. "Hair cells convert a mechan...is colleagues present evidence that the mysterious ion
channel is actually TRPA1. The TRP proteins are a trendy new family of ion
channels involved in sens...
Genomics research: New genetic 'hit list' may underlie susceptibility to sudden cardiac death
...elops in one or more of the genes that program the ion
channels of the heart. The ion
channels are "electrical tunnels" that produce and control the heart's electrical activity. A key fi...
...(known as lidocainein the US), which blocks sodium ion
channels. "There are two ways to stop a heart cell. Let it run out of gas- that's the potassium infusion-or to not even turn it on. That's what Dobson has done," says Jakob Vinten-Johansen, a cardiovascular physiologist at Emory University in Atlant...
Virtual mass spectrometry laboratory transforms learning experience
...pole mass spectrometer, an electrospray ionization ion
trap mass spectrometer and a magnetic sector mass spectrometer. (See Figure 1) The system connects the student to data files stored from one of the four mass spectrometers with one of three VMSL servers, two located at Carnegie Mellon and one at th...
Genetics of familial atrial fibrillation revealed, Science researchers report
... as KCNQ1 , which encodes a protein subunit of an ion
channel controlling the movement of charged potass...m channel. The KCNQ1 potassium channel, like other ion
channels, controls the electrical activity of the heart in excitable heart cells, or myocytes. That ...
Heart gone haywire blamed in some sudden infant deaths
...s electrical channels, he says. The electrical or ion
channels are proteins critical to orchestrating the electrical signals that prompt the heart to squeeze (beat) and refill between each heartbeat, says Ackerman, who is also director of the Mayo Clinic's sudden death genomics lab and the long Q-T synd...
'Control valve' within heart cells could protect body during heart attacks
... Nov. 1 issue of Science. The valve, actually an ion
channel on the walls of heart cells' energy-produc...urke says. "If we can determine how mitochondrial ion
channels regulate energy in heart cells, we may be able to protect the heart against life-threatenin...
Ouch! The receptors mediating acidic pain sensation
...c, both VR1 and a second nociceptor - acid sensing ion
channels (ASICs) - are activated. In previous experiments in mice, scientists have found that the activation of VR1 requires extremely severe acidification - pH less than 6.0. This suggests that another pain sensor plays a role in nociception, specif...
Chemists create synthetic cytochromes
... proteins, most commonly by bonds between the iron ion
and the amino acid histidine," said Suslick, a Wil...ed that a cyclic peptide would hold on to the iron ion
heme like a tight ring on a finger. In fact, the researchers found that their cyclic peptide binds ...
The Lancet neurology press release
...mechanisms by which mutations in genes that encode ion
channels may cause the attacks. Gene patenting-diagnosing the problem The US Patent and Trademark Office is currently processing patent applications for 50 000 DNA sequences. The companies applying for the patents hope that their sequences will tur...
Pivotal brain processor decreased in schizophrenia
...latory protein, involved in controlling receptors, ion
channels and other physiological factors and is activated and de-activated ultimately by neurotransmitters that are implicated in the development of schizophrenia," Greengard said. "A reduction of DARPP-32 required for functions in the brain could co...
Study finds a mouse model for episodic neurological disorders
...several times a day. The mutation affects calcium ion
channels tiny "gates" in cell membranes that control movement of electrically charged calcium ions into and out of cells. The movement disorder caused by this mutation is known as tottering syndrome in mice. The symptoms in tottering mice are simi...
Brain tumor therapy needs longer treatment time
...n imaging technique known as subcellular secondary ion
mass spectrometry (SIMS). The technique yields thr...29,000 grant to continue the cancer research using ion
microscopy. This article was prepared by Cornell News Service science intern Lissa Harris...
Wake Forest researchers find brain region 'exquisitely' sensitive to alcohol
...to alcohol." The cells in the thalamus possess an ion
channel that behaves differently depending on the ...nd disruption later in sleep. Godwin said that the ion
channels underlie normal sleep spindles are functioning normally early in sleep, and but may be turn...
Common diabetes drug causes arteries to spasm, endangering heart
...h eventually triggers the cell to open its calcium ion
channels. Calcium flows in, which signals the cell to secrete insulin. Unfortunately, a similar receptor exists on the smooth muscle cells that surround arteries, regulating flow through these vessels. The researchers found that mice without the re...
Mayo Clinic researchers find useful test for identifying patients
...e bridge between the molecular genetics of cardiac ion
channelopathies and the application of this knowledge in the diagnosis and management of these patients," writes James C. Perry, M.D., of Childrens Hospital in San Diego, Calif., in an accompanying editorial. Long QT syndrome is the first genetically...