Tag: "iop" at medical news

Breast MRI moderately useful for detecting breast cancer, but does not eliminate need for biopsy

In women with breast lesions that are suspicious for cancer, based on clinical examination or mammography, performing a breast MRI has high sensitivity but only moderate specificity for detecting breast cancer, but does not necessarily eliminate the need for tissue sampling, according to a study in the December 8 issue of ....... Mammography is the primary imaging modality used to detect clinica...

Magnetic resonance imaging helps detect breast cancer but does not eliminate need for biopsy

A multicenter study of 821 patients referred for breast biopsy based on prior examinations that suggested cancer finds that while magnetic resonance imaging (MRI) distinguishes between benign and malignant breast tumors better than mammography, biopsies are still needed to confirm the diagnosis. ...... The study, called the International Breast MR Consortium, was carried out in 14 university hos...

New biopsy technique helps assess breast cancer's spread

ANN ARBOR, Mich. -- A key question after a cancer diagnosis is whether the cancer has spread to nearby lymph nodes. Researchers at the University of Michigan Comprehensive Cancer Center have found a new non-surgical technique that can help doctors determine when breast cancer has invaded the lymph nodes, sparing some women an extra trip to the operating room....... The technique, which uses ultra...

Angioplasty, robotically assisted keyhole bypass combo appears effective

NEW ORLEANS, Nov. 9 Combining stented angioplasty and robotically assisted "keyhole" bypass surgery is safe and may help patients with extensive cardiovascular disease, researchers reported at the American Heart Association's Scientific Sessions 2004. ...Doctors performed the hybrid approach on 12 patients, all of whom remain free of chest pain, said Bernard De Bruyne, M.D., Ph.D., co-author of...

Biopharmaceutical manufacturing efficiencies signal reduced healthcare costs

October 13, 2004 (Washington, DC) Cost reductions associated with advances in large-scale biopharmaceutical manufacturing will play a role in reducing healthcare costs, according to a new industry joint publication by ASM Press, the book publishing division of the American Society for Microbiology, and BioPlan Associates. Advances in Large-Scale Biopharmaceutical Manufacturing and Scale-up Prod...

Limiting angioplasty to experienced hospitals will not reduce access to care

DURHAM, NC Standards of volume that limit angioplasty procedures to more experienced hospitals and physicians will not require most patients to travel longer distances for care, according to a new study by researchers at Duke University Medical Center and Duke's Fuqua School of Business. The findings should allay concerns about the effects of such standards on access to care for heart patients l...

FDA approves new labelling for Seroquel in bioplar mania

Alderley Park, UK — 23 July, 2004 -- ......AstraZeneca announced today that the U.S. Food and Drug Administration (FDA) has approved additional efficacy labelling information based on 12-week data for SEROQUEL (quetiapine), a psychotropic medication indicated for the treatment of acute manic episodes associated with bipolar I disorder. The data 1, part of the large scale effort to examine S...

Carbon monoxide from smoking helps keep arteries open following angioplasty

OAK BROOK, Ill.-In an unusual paradox, smoking cigarettes-a deadly habit that contributes to the development of peripheral artery disease-actually helps arteries stay open following a procedure to repair clogged blood vessels in the legs, according to a study in the June issue of Radiology. The study found that habitual to heavy smokers who continued to smoke after angioplasty had a lower rate of...

MRI-guided breast biopsy system is safe and efficient

It is now possible to safely and efficiently do a breast biopsy if a lesion is seen on MRI without sending the patient to surgery, a new study shows.... ..."In the past, if MRI detected a breast lesion, our only options would be to do a core biopsy or insert a wire in the area of the lesion; then the patient would have to go to surgery to have the lesion removed," said Constance Lehman, MD, PhD,...

Biopsy system is effective in completely removing benign breast masses

Benign breast masses can be safely and effectively removed without surgery--using a vacuum assisted breast biopsy system, preliminary results of a study show....... The study found that breast masses as large as 3 cm could be completely removed with just a small incision. The study included 24 patients, with 27 lesions, said Priscilla Slanetz, MD, director of breast imaging at Caritas St. Elizabe...

If core breast biopsy shows minimal abnormal cells, surgical excision is still necessary

Even if core breast biopsy results show only very minimal or focal evidence of abnormal cells, the lesion should be surgically removed to determine whether the woman has cancer, a new study emphasizes.... ...Researchers at Nyack Hospital in New York compared the core biopsy results to the surgical excision results of 24 women. The women in the study had undergone a core biopsy and the tissue that...

Study shows heart biopsy possible via arm catheterization

SAN DIEGOHeart biopsies, which are typically performed via catheterization through the groin or neck, are possible and may cause less discomfort for patients when performed through a vein in the wrist, according to a study by Penn State Cardiovascular Center specialists....... "Although not everyone is a candidate for catheterization through the wrist, called transradial catheterization, this stu...

Mount Sinai is best major hospital in New York City for angioplasty

(New York) -- The Mount Sinai Hospital has the best angioplasty outcomes of any major hospital in New York City, according to the latest report by the New York State Department of Health. The report also shows that the head of Mount Sinai's catheterization laboratory, Samin Sharma, MD, performs more angioplasties than any cardiologist in the state, and is the only one with risk-adjusted mortality...

CellCept's cardioprotective profile reinforced

Data presented today at the International Society for Heart and Lung Transplantation (ISHLT) annual meeting strengthens the body of evidence that CellCept (mycophenolate mofetil, MMF) has unique benefits for heart transplant patients as the only immunosuppressant that offers:...... superior survival benefits ... reduced coronary artery disease ... the least toxic side effect profile .........

Mycophenolate mofetil superior to azathioprine: Slows vascular disease progression after transplant

Researchers reported today that patients treated with CellCept (mycophenolate mofetil), a drug used to prevent rejection in organ transplantation, have significantly lower progression of intimal thickening, or thickening of the inner artery walls, compared with azathioprine (AZA). Intimal thickening is becoming increasingly important as a surrogate marker for long-term outcomes after heart transp...

Novel prostate cancer marker may lead to earlier diagnosis and fewer repeat bioposies

PITTSBURGH, March 11 Findings published in this month's issue of the Journal of Urology indicate that prostate cancer could be detected as many as five years earlier than it is currently being diagnosed by testing for a protein in tissue that indicates the presence of early disease. The researchers suggest that testing for the protein, EPCA, could serve as an adjunct to the current diagnostic ap...

Angioplasty clears clogged brain arteries

SAN DIEGO, Feb. 5 Angioplasty opened narrowed brain arteries, preventing strokes in patients for whom standard medication had failed, according to a study presented today at the American Stroke Association's 29th International Stroke Conference. ... "Angioplasty improves the outcome over what we would expect to see with medication alone," said study author Michael P. Marks, M.D., associate profe...

Imaging technique may diagnose breast cancer without biopsy

MINNEAPOLIS / ST. PAUL -- A technique that combines high-level magnetic resonance imaging (MRI) with a new spectroscopic method may result in an accurate, non-invasive way to make breast cancer diagnoses. In this technique, MRI is used to detect breast lumps, while spectroscopy measures molecules known to accumulate in cancer cells.... ...According to a study in the Nov. 21 online version of the...

One in four patients at risk if surgery delayed after failed angioplasty

ORLANDO, FLA. - Duke Clinical Research Institute and Canadian cardiologists have estimated that 25 percent of patients who unexpectedly require emergency heart surgery after a failed angioplasty are at risk of harm or death if any delays to the surgery are encountered....... While the number of patients potentially at risk is relatively low - between one and two per 1,000 angioplasty procedures -...

Emory scientists find oral tetrahydrobiopterin can reduce high blood pressure

ORLANDO - According to the American Heart Association (AHA), one in four U.S. adults has hypertension (HTN). Without adequate treatment, HTN can lead to stroke, heart attack, heart failure or kidney failure. In a presentation at the AHA's Scientific Sessions here today, Sonya Lefever, MD, a senior cardiology fellow at Emory, discussed findings by Emory researchers suggesting that oral tetrahy...

Multi-hospital angioplasty improvement effort reduces deaths and complications

ORLANDO, Fla. -- Angioplasty patients in Michigan are getting far better care - and suffering far fewer complications - than they used to, thanks to a cooperative quality improvement project involving local hospitals and Blue Cross Blue Shield of Michigan.... ...Now, a range of new research results show just how dramatic the project's effect has been. And, they provide new information that may he...

US women endure twice the surgical biopsies as British for same cancer detection rate

Although the rate of breast cancer detection is similar in the two countries, US doctors perform two to three times more open surgical biopsies than British doctors. In addition, American women are recalled, or referred for further testing, twice as often as British women, according to a study by UCSF radiologist Rebecca Smith-Bindman, MD.... ...Women in both countries who are recalled undergo ad...

Benchmark study of brain tumors points to resection over biopsy as one key to survival

CHARLOTTESVILLE, Va., Oct. 3 Patients with gliomas, the most common type of brain tumor, have a more favorable outcome with surgical resection in a craniotomy procedure that opens the skull than patients who have only a biopsy for a tumor, according to a study led by researchers at the University of Virginia Health System.... ...Results from the large, four-year study of 560 patients newly...

New model predicts likelihood of prostate cancer prior to biopsy

PORTLAND, Ore. -- A new, simple predictive model could reduce the number of unnecessary prostate biopsies by 24 percent without sacrificing cancer detection, according to a study to be published in the Oct. 1 issue of CANCER and available online beginning Aug. 25 at the Wiley InterScience Web site.... ... "While current prostate cancer screening practices are good at helping us find patients wi...

Ibuprofen could reduce cardioprotective effect of aspirin

A research letter in this week's issue of THE LANCET suggests that the painkiller ibuprofen could diminish the well-known beneficial effects of aspirin on preventing cardiovascular disease....... Aspirin makes platelets (blood-clotting cells) less 'sticky', which is associated with fewer thromboses (clots). Aspirin therefore reduces the chance of heart attacks caused by coronary thrombosis and st...

Nabi Biopharm's nicotine vaccine

Boca Raton, Florida, February 11, 2003 Nabi Biopharmaceuticals (Nasdaq: NABI) today announced that the U.S. Patent and Trademark Office has issued U.S. Patent No. 6,518,031, entitled "Hapten-Carrier Conjugates for Treating and Preventing Nicotine Addiction." The patent covers the composition of NicVAX, an investigational nicotine conjugate vaccine, the use of the vaccine to obtain antibody, and...

Emergency angioplasty OK without surgical back-up

CHICAGO, Nov. 17 Survival rates following emergency angioplasty for heart attack are the same regardless of the availability of on-site cardiac surgery, according to research reported today at the American Heart Association's Scientific Sessions 2002. ..."This is the largest study to date demonstrating the benefit of immediate angioplasty in acute heart attack patients," says lead researcher Tim...

Angioplasty safer, need for emergency surgery afterward plunges

DALLAS, Oct. 15 More physician experience and technological advances have produced a 10-fold drop in emergency bypass surgery following angioplasty, researchers report in today's rapid access issue of Circulation: Journal of the American Heart Association. ... It is routine to have a surgical team on standby in case complications arise during an angioplasty procedure. Angioplasty involves the i...

Angioplasty or medical therapy immediately after heart attack?

Authors of a study in this week's issue of THE LANCET suggest that there is no difference in treatment outcome of pre-hospital medical therapy with anti-clotting drugs or emergency angioplasty after severe heart attack. ... ...Although the use of anti-clotting drugs before hospital admission (prehospital fibrinolysis) and primary angioplasty (widening of the coronary arteries with balloon inflati...

Enzyme level linked to death after angioplasty

DALLAS, Aug. 20 A test commonly used to diagnose heart attacks may also identify patients at increased risk of death after balloon angioplasty, according to a study in today's rapid access issue of Circulation: Journal of the American Heart Association. ...Blood levels of the enzyme creatine kinase-MB (CK-MB) rise after a heart attack, indicating injury to the heart muscle. Measuring CK-MB is a...

Long-term effects of tirofiban similar to abciximab in patients having coronary-artery angioplasty

A follow-up study in this week's issue of THE LANCET helps to clarify the differences between two similar drugs in terms of their benefits for patients who undergo angioplasty for narrowed coronary arteries (the arteries that supply the heart with blood).... ...Platelet glycoprotein IIb/IIIa inhibitors reduce the clumping together of platelets in the blood, which can lead to complications during...

XALACOM more effective than Cosopt for IOP reduction in patients with glaucoma or ocular hypertens

Fort Lauderdale, Florida, USA (May 8, 2002) XALACOM (fixed combination latanoprost 0.005% and timolol 0.5%) once-daily is more effective for the reduction of intraocular pressure (IOP) than Cosopt (fixed combination dorzolamide 2% and timolol 0.5%) twice-daily in patients with open-angle glaucoma or ocular hypertension, according to a study presented at the annual conference of the Association f...

Mild kidney disease doubles risk of death after angioplasty or bypass

DALLAS, April 23 The more than 3 million Americans who have mild kidney disease may be at increased risk of complications following procedures to open or bypass blocked arteries, according to a study published today in Circulation: Journal of the American Heart Association. ...During a seven year follow-up study, researchers found that people with mild chronic kidney disease (CKD) face double th...

Biopsies of the internal mammary sentinel nodes may improve patients chances of survival

Surgeons at a hospital in the Netherlands are pioneering the taking of biopsies from lymph nodes behind the sternum (breast bone) at the same time as they take the more usual biopsies of the lymph nodes under the armpits, the 3rd European Breast Cancer Conference in Barcelona heard today (Friday 22 March). ......Dr Fred van der Ent, a senior surgeon at Maaslandziekenhuis, in Sittard, said that th...

Miniature filtering device to make angioplasty safer being tested

Cardiologists at Rush-Presbyterian-St. Luke's Medical Center in Chicago are currently testing a new miniature-filtering device designed to make angioplasty safer. Rush is among 50 medical centers in the country, and the only medical center in Chicago, testing the device. ... The device, called CardioShield from Ireland-based MedNova, catches small particles of debris that can come loose when an...

Imaging technique predicts success of bypass surgery or angioplasty

. CHICAGO --- An advance in magnetic resonance imaging (MRI) developed by researchers at Northwestern University Medical School and Siemens Medical Systems has radically improved the ability to determine which patients with coronary artery disease will benefit from bypass surgery or angioplasty.. . The investigators, led by Northwestern cardiologist Raymond J. Kim, M.D., and basic scientist Rob...

Emergency angioplasty or bypass surgery saves lives of heart attack patients with cardiogenic shock

. Heart attack patients with a life-threatening complication called.cardiogenic shock experience an improvement in survival at 6 months when treated.with balloon angioplasty or coronary bypass surgery compared to patients who.receive intensive medical care to stabilize their condition, according to a.study funded by the National Heart, Lung, and Blood Institute (NHLBI).. The resul...

Lowering 'bad' cholesterol as good or better than angioplasty for mild coronary artery disease

. Aggressively lowering "bad" cholesterol "is at least as good or better".than angioplasty/usual care for preventing and delaying certain cardiac events.in selected patients with stable coronary artery disease, report researchers.from Emory University and elsewhere in this week?s New England Journal of.Medicine.. . The authors report results of the Atorvastatin Versus Revasculariz...

Misdiagnosis Looms As Demand Increases For New Breast Cancer Biopsy

.CHAPEL HILL, N.C. - A multi-center study published in The New England.Journal of Medicine last October showed that sentinel lymph node biopsy - the.removal of some of the first lymph nodes into which cancerous cells from the.breast might drain - is as effective for determining the spread of disease as.totally removing all the lymph nodes under the arm.. . That journal report and subsequen...

Pairing Two Drugs With Angioplasty May Offer Best Success In Treating Heart Attacks

. DALLAS -- Combining a "super aspirin" with bursts of a clot-busting drug.during an angioplasty for patients experiencing a heart attack could offer the.best strategy to quickly and safely open clogged arteries, Duke University.researchers said at the annual American Heart Association scientific sessions. . Results of a dose-ranging trial show that using abciximab and two.low-dose...
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