Chemists Develop Probe To Detect Changes In Imaging Agents Inside Body
...mportant compounds such as brainimaging agents and kidney imaging agents, but he realizes a lotof research remains to be done. "We've just demonstrated that we have the capability to dothis, so it's opened up a frontier. We've opened the door, but wehaven't taken too many steps yet." In fact, all of the pre...Tacrolimus Stops Rejection Of Kidney Transplants
...emonstrate such encouraging results for persistent kidney rejection. The study, which involved 73 patients w... provides prompt, effective reversal of refractory kidney rejection, good long-term kidney function, a low incidence of repeat rejection, and an acceptable sa......-A year after doctors gave up on William Hines,his kidney tumor is gone and his life is back to normal. Hine...asibility study focusing on patients with isolated kidney tumors smaller than a tennis ball and no other hope. In the procedure, Lewin inserts a probe...Researchers Gain Insights Into Drugs Used For Manic-Depression
...ery effective but it can cause gastrointestinaland kidney problems, weight gain and grogginess, making many people want tostop using it. At higher levels the drug can be highly toxic," said UWMedical School professor of pharmacology Lowell Hokin. "Valproate does notproduce the same toxicity." Hokin...New Test May Improve Treatment Of Kidney Disease
Why some patients with kidney diseases respond well to certain medicationsand others do nothas continued to stump physicians. With no means to test the medicationsbesides trial and error,finding the right treatment is often a frustrating experience for physicians andtheir patien...NIH Honors Emory Researcher With Merit Award For Work On Renin-Angiotensin System
...try, 1989). When blood pressure drops, the kidney attempts to counterbalance thedrop by releasing the enzyme, renin. Renin in turn catalyzes the production ofangiotensin, a hormone circulating in the blood. The ACE enzyme converts theinactive form of angiotensin-'antiotensin I' to angiotensin II, wh...Organ Rejection Drug Also Shows Promise For The Treatment Of Kidney Disease
...escomplicated by fluid retention and early loss of kidney function," says WilliamA. Briggs, M.D.,lead author...eglomerulus, a network of blood capillaries in the kidney that filters wasteproducts from theblood. Patients took the MMF pills twice a day for an average of...Diuretics And Beta-Blockers Are Best Drugs To Combat High Blood Pressure, Study Finds
...damage to retina, heart, peripheral blood vessels, kidney or central nervous system -- all organs that are affected by high blood pressure. Each time a patient visited an HSTP clinic, the staff recorded items ofclinical importance, especially blood pressure and medication data. Somepatients were tak......s of cisplatin andcarboplatin have a major risk of kidney toxicity (cisplatin), nausea andvomiting, bone marrow suppression, neurotoxicity and other toxicities. BioNumerik has designed BNP7787 to enhance selective inactivation of toxicplatinum drug species and to produce a less toxic drug relative to otherp...Researchers Identify Candidate Immunosuppressant With Fewer Side Effects
...y that activates T cells. But both drugs can cause kidney andnervous system damage, making them unsuitable for wider clinical application.The newly identified peptide prevents a single, specific step in the immunesystem's signaling pathway, so researchers anticipate that it will not causeserious side effect...Compound In Meat Prevents Diabetes, Study Suggests
... If left untreated, Type II diabetes can result in kidney problems, amputation of limbs, blindness, coronary heart disease or strokes. The research on CLA's ability to control Type II diabetes was published in the March 27 issue of Biochemical and Biophysical Research Communications and will be presented at......od of these side effects. Significant neurologic, kidney orliver toxicities were rare in both groups. The mechanism of suramin's action is complex, said Small, and still has not beenfully delineated. Prostate cancer, the most common cancer in men, accounted for more than 40,000deaths in the United States...Wistar Scientist Awarded American Cancer Society Grant For Study Of Tumor Suppressor Proteins
...cancers. Lung, breast, brain, bone, skin, bladder, kidney and ovarian cancers all share acommon characteristic -- the gene regulating the activity of P16INK4, whichfastens itself to the CDK4 inhibitory protein, is either deleted or mutated. The consequence of this genetic alteration is that the P16INK4 prot...Synthetic Detergent Found To Fight Multi-Drug Resistance
...ough its role in these tissues is notknown. In the kidney it functions by moving substances from blood in th... and into urine. "For decades the kidney has been identified as playing an important rolein protecting the body from natural and synthetic ch...ACE-Inhibitors Score High In Reducing Heart Attack Deaths
... Those taking the drug also had double the rate of kidney problems: 1.3percent in the drug group versus 0.6 percent in controls. The researchers lackdata on whether those conditions improved when treatment was stopped. Those twocomplications were much more common in people over age 75, and there was noevid...Pioneer In Nuclear Medicine Wins Lifetime Award
...agnosis ofinfections, coronary artery disease, and kidney diseases, among others. Manytimes, Wagner himself was the experimental subject. In 1983, his lab accomplished the first imaging of neuroreceptors in thebrain. Their pinpointing of the dopamine receptors inside the brain led to muchwork in ad......one traditionally envisions usingsound to break up kidney stones and to take pictures of fetuses. In intriguingexperimental studies, scientists are demonstrating that ultrasound can performsurgical tasks such as break up tumors, remove unwanted tissue, and stopinternal bleeding. Naren Sanghvi of Focus Surg...New Elementary School Program Lowers Cardiovascular Risks In Children
...ood, where they can cause heart attack, stroke, or kidney failure. Dr. Harrells investigation provides encouraging evidence that we can act to counter these prevalent conditions -- starting with our children. And we can do it with limited resources. CHIC research results showed that both classroom-wide an...Controlling Collagen Levels May Be Key To Fighting Organ Failure Caused By High Blood Pressure
...ndividuals areat risk for heart failure as well as kidney and other organ failure, accordingto a study in today's Circulation: Journal of the American Heart Association. How high blood pressure contributes to organ failure has not beenunderstood. However, researchers from the University of Navarr...Mini-Pill Increases Risk Of Chronic Diabetes In Women With History Of Diabetes During Pregnancy
...disease, stroke, nerve disease,vision problems and kidney failure. Lifestyle changes (such as dietary changesand increasing exercise) and oral medications prove effective in controllingdiabetes for most people. "Family planning is extremely important for women with a history of gestationaldiabetes," says st...