Tacrolimus Stops Rejection Of Kidney Transplants
... or reverse unmanageable rejection of transplanted kidneys in three out of four cases says a report from 13 o...rolimus therapy may reduce the 10 to 15 percent of kidneys that are lost to repeated or uncontrollable rejection to only two to four percent, a significant adv...Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
...ntestines, where it preventsabsorption, and in the kidneys and liver, where it promotes elimination of thechemicals it recognizes. That may help explain why the blood levels of proteaseinhibitors, despite administration at comparable doses, can vary so widely amongindividual patients, Kim said. "Beca...Treatment Of Distal Ureteral Stones: ESWL Versus URS: A Prospective Randomized Study
...es, 10 to 12 inches long, that carry urine fromthe kidneys to the bladder. Distal stones are usually found at the far end ofthe ureter, closer to the kidney. About 90% of urinary stones can be seen on Xrays. These investigators studied two first line approaches to distal ureteralstone removal: extracorpo...Maternal Tissue Typing Could Improve Selection Of Kidney Transplant Donors
...esearch team compared transplant survival rates of kidneys donated by HLA-identical siblings of recip... long-term survival rates of HLA-identical kidneys were the same as HLA-mismatched kidneys, provided the donors’ mismatched HLA antigens w...Hardening Of The Aorta Increases The Risk Of Stroke
...eamtoward the blood vessels that feed the brain or kidneys or other organs. Butit's also likely that patients with the disease in this very early part of theaorta also have atherosclerosis throughout the body." The investigators hope to test available therapies to learn whether theycan lower the risk...Anabolic Steroids May Help Dialysis Patients Fight Fatigue And Gain Lean Body Mass
...s, is amedical procedure employed when a patient's kidneys cannot properly clean theblood of toxins and waste products. A patient's blood is removed from the bodyvia a tube inserted in a vein, filtered by a dialysis machine, and thenreplaced. Typically, this process must be repeated three times a week and t...Statement from Claude Lenfant, M.D., NHLBI Director, on Trends in Hypertension
...hypertension. Untreated hypertension candamage the kidneys and lead to stroke, heart attack, and heart failure. Heartdisease and stroke are the first and third leading causes of death,respectively, in the U.S. Hypertension is defined as systolic blood pressure averages of 140 mm Hg orgreater and/or diastolic......eyer. "The lungs are much moreprone to injury than kidneys and livers," he noted. "Unlike kidneys and livers,with lungs there's no time to do tissue matching--we have to transplant the lungquickly."...Transplant Pioneer Thomas E. Starzl Most Cited Researcher In Clinical Medicine Over Past 17 Years
...ight, making it more feasible totransplant livers, kidneys and hearts. In 1989, he and his team announced theirdevelopment of an even more effective drug therapy to prevent rejection oftransplanted organs. This drug, FK506 or tacrolimus, won U. S. Food and DrugAdministration approval in 1994. In addition ...New Strategy May Succeed At Extending The Life Of Transplanted Kidneys
...ew strategy to extend the function of transplanted kidneys shows promise. In a study of 60 people who had re...refore may have a different effect on transplanted kidneys over time. "Many kidney transplant patients, especially those whose kidneys came fromcadaver donors,...Kidney Transplant Recipients Require Less Long-Term Care If They Receive Well-Matched Donor Organs
...r patients could drop dramaticallyif more received kidneys closely resembling their own organs. Doct...lf, the data could be used to argue that all donor kidneys shouldbe available nationally so less mismatched transplants occur. Congress isdebating the merits o...New Procedure Makes A Successful Transplant Possible
...gdonors between March 1998 and April 1999, and the kidneys continue to function.The concept of using plasmapherisis in patients with high PRA has been aroundsince the 1980's, and a few cases had been reported in the U.S. and in Europe,but with low success rates," says Dr. Schweitzer. He believes the newanti-...The 'Break Even' Cost Of Kidney Transplants Is Shrinking
...That analysis was done on 227patients who received kidneys from living donors from March 1996 to December1998...ome. In addition, the increased use ofliving donor kidneys can reduce costs, since those kidneys tend to functionbetter right after the transplant than those f...Kidney Transplants From Living Donors Reduce Long-Term Costs Of Care
...s treatments would be forfive years. Giving people kidneys from deceased donors, the most plentifulcurrent so... says. Half of the people who receive living donor kidneys still havethem after 15 years, and kidneys from cadavers tend to last 10 years on average. I...Milestone study in development of xenotransplantation
...loodperfused outside the body through pig spleens, kidneys or livers. Samples fromthese patients were tested using the most advanced, state-of-the-art technologyavailable. The protocol included three different tests to see whether there hadbeen any infection by or transmission of the pig virus. Samples fro...Double transplant frees patient from need for immunosuppressive drugs
...ing no other viable option. Her myelomacaused her kidneys to fail, and she did very poorly on dialysis. Her cancermade her ineligible for a regular kidney transplant, and her kidney failure madeher unable to tolerate the toxicity of standard bone marrow transplantpreparation. After the double transplant f......k to the patient." Because the need for livers and kidneys is rising much more quickly than thenumber of organs becoming available, Dr. Shackleton and his colleagues willcontinue to employ the latest procedures to make the best use of cadaver organsand those provided by living donors. "If we look at the grow...Research shows low lead in body can cause spontaneous abortion
... thenervous system and at high doses to injure the kidneys and reproductive systems,Hertz-Picciotto said. The metal easily crosses the placenta to developinginfants. Borja-Aburto earned his Ph.D. in epidemiology at UNC-CH's School ofPublic Health in 1995 and now directs the National Center of Environ...NIAID spearheads collaborative network for clinical research on immune tolerance
...val oftransplants. More than half of transplanted kidneys fail to survive 10 years. Attempts at islet transplantation, an experimental therapy that replacespancreatic islets destroyed by type 1 diabetes, have been even less successful. Only about 5 percent of people with diabetes who receive transplanted i......of the body; and enlargement of the liver, spleen, kidneys and heart. Earlier this year, scientists with Sensus, which holds the license for the growth hormone antagonist technology, announced the results of Phase III clinical trials of the growth hormone antagonist drug pegvisomant. The trials were conduct...