Penn study shows that head trauma produces Alzheimer's-like neurodegeneration
...ential Clinical Application The study also lays the scientific foundation for the furtherinvestigation into the neurodegenerative process so that appropriate therapeuticagents may be developed to slow or block the process resulting from head injury. "This study adds to the body of knowledge that m...Moderate levels of worry can motivate women to get mammograms
...y fail unlessthey also include an action plan that lays out how the desired health behaviorcan be achieved." The investigators studied 213 women who participated in an education and riskassessment program for people with a family history of breast cancer, ovariancancer or both. The women, who ranged in a...Reversing DNA damage caused by the sun before it becomes skin cancer may be possible
...timistic. "I'm pretty excited about it. This lays the foundation for a [potential] drug. I think it's promising." If the artificial enzyme is successful in the upcoming DNA tests, it will likely go through many modifications as it proceeds through further laboratory testing. Then, it would h...Researchers identify for the first time proteins vital to maintaining nervous system architecture
...vous system architecture after the developing body lays down the wiring pattern. The finding may someday lead to a better understanding of some neurological diseases but, for now, is changing neuroscientists' fundamental understanding of nervous system anatomy. The investigators, led by Dr. Oliver Hobert,...Dartmouth team finds uneven relationship between newborn intensive care and death rates
... that correlates poorly with improved survival. It lays the groundwork for reassessing the allocation of resources to improve newborn health and prevent disease and death, and raises questions about the continued growth of specialty medical services in the United States. The advent of neonatal intensive ...Scientists become filmmakers to decipher immunity
...that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. The Institute's programs encompass the areas of cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, bioinformatics, c...Virus that can infect both mice and humans is driven to extinction with cancer drug
...ruses," commented Dr. Lowenstein. "This work also lays the groundwork for future studies to determine how mutagens actually slow down the replication process and, at the same time, may lead to new treatments that succeed where others have limited effectiveness." Although viral extinction was likely due ...$15 million grant spurs cancer collaboration; M. D. Anderson, University of Puerto Rico
...ions to learn from the successes of the other, and lays the building blocks for developing more advanced therapies for patients with cancer. "By learning from physicians already treating patients in Hispanic populations, we will increase our own sensitivity to minority needs," continues Gibbs. "It is our ...Assistance program for families of critically ill patients expands across the U.S.
...list for program coordinators. The design section lays out the plan and explains how to get organized; the implementation section demonstrates success factors. The evaluating and improving sections outline critical components of the replication process and the sharing section provides tools to facilitat...New standard proposed for coronary artery calcium screening
...d medium-size patients. The consortium's research lays the groundwork for a database that will reference a patient's calcium score against the scores of others who are the same age and gender. "The clinical success of CT scanners for detecting and quantifying coronary artery calcium requires some method...How the cellular 'garbage disposal' grinds to a halt to cause Batten disease
...am from the University of Rochester Medical Center lays out the sequence of biochemical steps that results in the disease. The team led by David A. Pearce, Ph.D., of the Center for Aging and Developmental Biology found that the genetic defect is linked to a protein that regulates the amino a...UCSF scientists show prion shape affects nature of infection
...ape change accounts for strain differences, and it lays the groundwork for research to determine the physical differences that allow a prion to change shape and cause different diseases. Answers could lead to strategies to block the folding or its route to disease, the scientists say. The UCSF discovery i...Mayo researchers invent targeted imaging probe to aid early Alzheimer's diagnosis
...imer's disease. This advance using laboratory mice lays the foundation for the first imaging-based diagnostic test for living Alzheimer's disease patients. The new technique is currently used only with specially-bred laboratory animals, but is expected to move to human trials if these early results are su...It's a gamble: Dopamine levels tied to uncertainty of rewards
...inted in our quest for those rewards. The research lays a foundation for a better understanding of what happens in the brain during unpredictable reward situations such as gambling and offers promise for exploring the chemical foundation of problems such as gambling addiction. "We're moving to a point whe...Study lays down genetic basis for sinus disease and nasal polyps
...s specific to raising levels of CC10." "This study lays the initial groundwork for additional studies on what has been up until now a poorly understood and confounding illness," said Kim. "We now have many lead candidate genes which may play a role in causing sinus disease. These studies may lead to new...Scientists pinpoint flaw, offer new promise for stroke treatment
...pase-8, which goes on to activate caspase-3, which lays waste to a cell's nucleus. "This study sheds a lot of light on why tPA is not as effective as it could be. TPA is tremendous at opening up blood vessels, but problems with toxicity diminish the positive effects," says Zlokovic, who is professor in t...No increase in deaths for heart failure patients with pulmonary artery catheter
...nd treat this serious condition. The ESCAPE study lays to rest concerns that use of a pulmonary artery catheter in patients with advanced heart failure is associated with increased death and hospitalization. At the same time, the study suggests that PAC should not be used routinely to guide therapy. Th......order tooptimize its entire research portfolio and lays out a vision for a moreefficient and productive system of medical research. For more informationabout the NIH Roadmap, please visit the Web site at: http://www.nihroadmap.nih.gov ....