New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
...MD, UCSF professor of medicine and epidemiologyand lead author of the study. Cummings presented his findings today (May 18) at the annual meeting of theAmerican Society of Clinical Oncology. UCSF researchers found that the osteoporosis prevention drug, raloxifene,drastically reduced the risk of breast can...Metrifonate, A New Alzheimer Drug, Helps Behavior Problems
...e ResearchCenter, participated in the study. He is lead author of a paper in the May issueof the journal Neurology that presents the results. Bayer Corp. funded theclinical research at 24 sites in the United States, including WashingtonUniversity School of Medicine. Morris reviewed the resulting data as a...Drug's Effect On Chromosomes May Explain Second Cancers
...ever, etoposide causes chromosomaldefects that can lead to secondary leukemias. These leukemias often aris...ve been linked to the drug. “This damage may lead to a rearrangement of genetic informationthat unmasks oncogenes or other secondary mutations that ca...Effective Obesity Treatment Likely To Require Targeting Of Multiple Weight Control Systems
...rstanding of the weight control system will likely lead to drug combinationsthat are effective in treating obesity. We can be encouraged that treatmentswill improve, but we must be realistic that multiple systems must be targetedfor long-term weight control to be effective. No single intervention is likel...New Radiation Procedure Targets Liver Malignancies
...rnelius McGinn, M.D., a radiation oncologist and lead investigator on the U-M liver cancer study. For 10 years, U-M researchers William Ensminger , M.D., Ph.D., Theodore Lawrence, M.D., Ph.D., and Randall Ten Haken, Ph.D., have investigated the use of focal liver irradiation along with chemotherapy del......he clinical use of CRH-antagonists could therefore lead to a fasterand more effective therapeutic response than classical antidepressants, andrepresents a completely new mode of action....Synthetic Detergent Found To Fight Multi-Drug Resistance
... "We're very surprised by these findings," says lead investigator Dr.Jeffrey Charuk of the department of medicine. "While the synthetic chemical isprobably too low to interfere with the action of the drug pump it might be auseful adjunct to standard chemotherapy treatments, along with other relativelyn...States Must Be Held Accountable For New Health Plans For Children
...ences. Untreated ear infections, for example, can lead tohearing loss or deafness. Language or other developmental delays resulting fromuntreated neurological problems can inhibit normal development and socialinteractions. Uninsured and underinsured children presently receive a patchwork of care from"sa...Abstinence Reduces HIV For High-Risk Women - Even Those Who Relapse - Study Shows
..., atemporary reduction in risky behavior can still lead to diminishing the spreadof the HIV infection." The article appears in a special issue about AIDS in Interfaces: AnInternational Journal of the Institute for Operations Research and theManagement Sciences. Dr. Brandeau is the issue's special editor. ...Crystal Structure Of gp120 Reveals HIV In Action
...Ph.D., associate research scientist atColumbia and lead author on the first Nature paper, "Knowing the structure downto the atomic details will provide valuable clues for vaccine design." X-ray crystallography is a technique that passes X-rays through acrystal from many angles, determines their...Stopping High Blood Pressure Drugs May Start A Stroke
...igh blood pressure and increased stroke risk, says lead authorAmanda G. Thrift, Ph.D., of the department of epidemiology and preventivemedicine at Monash Medical School in Australia's Victoria province. The three-year study analyzed medical records from 331 individuals whohad a bleeding stroke, c...18 Millionth Chemical Substance Entered In World's Largest Database Of ChemicalInformation
...vertheless, some ofthese substances may eventually lead to new medicine, materials, or otherimportant discoveries.) The 18 millionth substance was registered on June 15, 1998, selected from aWorld Intellectual Property Organization patent application of April 30, 1998from Merck & Co., Inc. Chemical Abstra...One-Time Needles Don't Reduce HIV Among Addicts, Study Shows
...f RAND and Carnegie Mellon University, the study's lead author and anauthority on drug policy. The study appears in a special issue about AIDS in Interfaces: An InternationalJournal of the Institute for Operations Research and the Management Sciences.Dr. Kaplan, the author of a seminal study supporting ne...Safe And Effective Treatment For Acute Repetitive Seizures
... research on the brain and thenervous system and a lead agency for the Congressionally designated Decade ofthe Brain. *Dreifuss, F.E. [deceased], Rosman, N.P., Cloyd, J.C., Pellock, J.M.,Kuzniecky, R.I., Lo, W.D., Matsuo, F., Sharp, G.B., Conry, J.A., Bergen, D.C.,Bell, W.E. "A Comparison of Rectal Diaze...International Panel Evaluates Testing For Drug Resistance In HIV
...ot totally suppress viralreplication will probably lead to the proliferation of resistant strains. Therefo...amounts. Also, becauseprevious drug treatment may lead to the survival of resistant strains--even atundetectable levels--interpretation of any resistance a...New Guidelines Stress Early Potent Drug Cocktails, Individualized Therapy
... UnitedStates, Europe and Japan, says the report's lead author, Charles Carpenter M.D.,a professor at the Brown University School of Medicine based at the MiriamHospital in Providence, R.I. An audio recording of a symposium on the reportwill be available Wednesday evening, July 1, at http://www.webcast.a...Ulcer Drug Linked To Birth Defects
...acial paralysisknown as Mobius syndrome," explains lead researcher Anne Pastuszak, MSc, ofHSC's Motherisk program and director of the University of Toronto FetalDiagnosis and Treatment Centre. "The drug is not recommended for use inpregnancy because it may stimulate uterine contractions and cause vaginalb...Voluntary HIV Counseling And Testing Reduce Risk Behavior In Developing Countries
...ng countries to curb sexual riskbehaviors that can lead to HIV infection, according to new research findings."We designed a study to definitively answer whether it is cost effective toinvest in these services in the developing world, and the simple answer is 'yes'", said Thomas J. Coates, PhD, director of...Extreme Prematurity Brings Two-Fold Increase In Risk Of Repeating A Grade, Needing Special Education
...professor of social and preventive medicine, and a lead author on the study. "What we found through this research was that rescuing these babies has not exaggerated the burden from pre-surfactant days. Many children do have trouble in school, but the level of special education needs has remained fai...Answers To Access, Adherence And Tolerance Of Protease Inhibitors
...c side effects, followed bytreatment failure, says lead author Valerie Stone, M.D., director of the HopeCenter for HIV Care at Memorial Hospital in Pawtucket, R.I., and an assistantprofessor of medicine at Brown University. "Patients can only benefit from protease inhibitors while they are taking thepills...