Researchers discover potential skin cancer prevention target
... a topical cream to treat sunburns or precancerous lesions to prevent progression to cancer, he says. Signal transducers and activators of transcription 3 (STAT3) belong to a class of proteins called transcription factors that can lead to cancer by allowing a healthy cell to respond inappropriately to exter...No justification for colposcopy in screening of young women for cervical cancer
...y is the best way of monitoring low-grade cervical lesions among adolescents and young women. Around 70% of ...ection develop low-grade squamous intra-epithelial lesions (LSIL); although LSIL are usually benign and disappear over time, they can develop into high-grade l...The effect of osteoporosis drugs on osteoarthritis of the knee
...hickening, osteophytes, and bone marrow edema-like lesions than the women not taking these medications. "This finding is particularly important because the MRI bone marrow abnormality score appears to be a strong predictor of progression of structural deterioration in knee OA," Dr. Carbone notes. ...News tips for Monday, November 8, 2004
...ents underwent the microwave technique ablation of lesions causing AF concurrently with surgeries, including heart valve replacement or repair and coronary artery bypass surgery. One patient had only AF ablation. After microwave treatment, only 17 percent stayed in AF immediately after surgery. One had a ...New magnetic percutaneous system navigates vessels
...gnetic system is useful in patients with difficult lesions who are undergoing a coronary intervention, such a...ed because of their potentially difficult to cross lesions during angioplasty. Fifty-four percent of the patients had diabetes mellitus, a patient population e...Angioplasty, robotically assisted keyhole bypass combo appears effective
...ery (LAD). "Patients with diabetes often have long lesions in their LAD that are difficult to treat with angioplasty but can be helped with bypass surgery," De Bruyne said. "They also have a greater risk of infection if you open the chest and are more likely to have a long period of healing; therefore, avoi...Researchers are studying photodynamic therapy
...Administration in 1999 to treat pre-cancerous skin lesions of the face or scalp. In this study, researchers investigated anaerobic bacterial strains (bacteria that can only survive and grow in the absence of molecular oxygen) and facultative anaerobic bacteria (bacteria that can survive without oxygen). "T...Chemoprevention backgrounder: Working for a future of cancer chemoprevention
...ct like an anti-cancer drug, stopping precancerous lesions in the mouth and throat from morphing into tumors. Green tea has long been suspected of having beneficial health effects, based on decades of research conducted in China, Southeast Asia and Japan. "Epidemiological studies conducted in the 1980s sugg...Post-therapy damage in medulloblastoma patients can be mistaken for new tumors
...demonstrates that this damage, called white matter lesions (WMLs), can be mistaken for recurrent cancer, prom...of early-onset WMLs--that is, how frequently these lesions occur in patients with medulloblastoma or PNET who have been treated with radiation and high-dose ch...Surgery without the scapel: U. Va. Health System marks fifteenth anniversary of Gamma knife
...o be effective treatment for residual or recurrent lesions after conventional surgery. Patients with malformed blood vessels in the brain, a condition called arteriovenous malformation (AVM) are also experiencing high success rates-- about eighty percent. Patients may also be potential candidates for t...Early results shed light on lung cancer screening advance
...er Screening Trial (NLST). LDCT can identify small lesions than x-ray, however, studies have yet to show any improvement in lung cancer mortality using the test. Paul F. Pinsky, Ph.D. of the National Cancer Institute in Bethesda, Maryland and his colleagues reviewed medical records pertaining to the follow...FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS
...eveloped no new or newly enlarging T2 hyperintense lesions compared to 22 percent of placebo-treated patients...eveloped no new or newly enlarging T2 hyperintense lesions compared to 40 percent in the AVONEX plus placebo group (p "I believe TYSABRI will be an important t...Computer program helps doctors diagnose lung cancer
...and may actually help radiologists identify benign lesions and reduce the number of people undergoing biopsies. Researchers hope next to develop a system that will both detect a lesion and identify it as malignant or benign. In addition to Hadjiyski, researchers were Berkman Sahiner, Ph.D., associate profess...Imatinib (Gleevec) has activity in AIDS-related Kaposi's sarcoma
...DS-defining illness characterized by soft purplish lesions on the skin, mucous membranes, and internal organs... stabilized and they were no longer developing new lesions after four weeks. Biopsies of patients' tumors demonstrated that these responses correlated with inh...UCSD researchers identify new role for drugs in prevention, treatment of atherosclerosis
...the accumulation of cholesterol in atherosclerotic lesions by up to 70 percent, as compared to untreated mice fed a high cholesterol diet. The scientists also determined the molecular pathways taken by the two versions of the PPAR drugs, a finding that could potentially be used to develop new anti-atheroscl...Breast MRI moderately useful for detecting breast cancer, but does not eliminate need for biopsy
In women with breast lesions that are suspicious for cancer, based on clinical ...y. Previous research has indicated that additional lesions seen by MRI that are not visible on the mammogram have been reported to be present in between 27 per...Add an 'E' to the alphabet for identifying melanoma
...9 pigmented lesions, dermatologists noted that the lesions that had changed were at least four times more likely to be melanoma than the lesions that did not change. "An evolving lesion is one which is changing in terms of the fiv...Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
...ation. "Currently, the best treatments for skin lesions associated with psoriasis are topical steroids, but the problem with those drugs is that they're not selective for the disease-causing cells. They affect normal cells as well, and repeated use over time can lead to tissue destruction," said Gary Glic...M. D. Anderson researchers discover key protein in psoriasis
...exhibits all the major features of human psoriatic lesions and shown we can reverse those steps," said John D... found high levels of activated STAT3 in psoriasis lesions in 19 of 21 patients. Based on this observation, the researchers decided to develop a mouse model in......distinguished from MS by the extensive spinal cord lesions it inflicts spanning three or more segments of the bony spine, and by lack of MS-type lesions found by magnetic resonance imaging of the brain. About the Investigation Blood samples were take...