Enigmatic role for NF-kappaB in the hardening of arteries
... from the blood that consume LDL, thereby creating lesions that ultimately cause vessel narrowing and restric...e advanced, and contained more necrosis, and early lesions contained more macrophages. The authors suggest that inhibition of the NF-kappaB pathway may increas...Cognitive impairment worse than expected in seniors, says University of Pittsburgh study
...multiple problems, such as small "silent" ischemic lesions in the brain, depression, use of psychiatric medications, or other disease processes that can affect the brain (including chronic liver and kidney failure) rather than the onset of Alzheimer's. MCI is a heterogenous condition that affects the areas o...Jefferson Scientists define new cell type that may lead to clues about Kaposi's sarcoma
...her factors and see if they can induce these early lesions to behave like the natural history of the human lesion."...Tumor size predicts survival in patients with lung cancer
... may be useful in discovering even the smallest of lesions that can, in turn, represent early-stage lung disease." "Although further substaging of early-stage lung tumors may be necessary to accurately assess and treat patients with lung cancer, routine CT [computed tomography] screening for the detection of...OHSU researchers study recent monkeypox outbreak
...all. If the symptoms were very mild, then no 'pox' lesions would develop on the skin and those people may have thought they were simply suffering from the common cold or may not have even noticed that they were sick. Therefore, it is possible that some cases of monkeypox went undiscovered or were under-repor...New treatment appears effective for rosacea
...elaic acid gel to the face reduces the redness and lesions associated with rosacea better than a commonly use...n the nose and cheeks and sometimes accompanied by lesions that appear similar to small pimples. According to the article, rosacea usually fist appears in peo...High nuclear grade associated with recurrence of in situ breast lesions
... have a recurrence. Women with high-nuclear-grade lesions had a 5-year risk of an invasive recurrence of 11....tially detected by mammography, women with initial lesions detected by palpation were more likely to develop recurrence as invasive cancer than women with lesi...Inflammation of placental membranes may be risk factor for cerebral palsy
...onprogressive motor impairment syndromes caused by lesions of the brain arising early in development, occurs in 1 to 2.4 per 1000 live births. Half of all cases of CP occur in term infants, for whom risk factors have not been clearly defined. Recent studies have suggested a possible role of chorioamnionitis....Computer-assisted breast imaging systems help find and characterize cancers
...the field by improving mammogram classification of lesions as malignant or benign, enhancing breast ultrasound imaging, aiding with detection and classification on film and digital mammograms, and allowing precise tracking of an individual woman's case over time. The U-M team is also working on their ultima...Surgery without radiation inadequate for DCIS, study reveals
...tients, the rate of recurrence (both repeated DCIS lesions and more-serious invasive cancers) rose to a level...s. Physicians believe that some proportion of DCIS lesions eventually spread beyond the milk ducts and become potentially dangerous invasive cancers. However, ...Moderate alcohol use may be associated with brain shrinkage
...ewer brain infarcts (dead tissue) and white matter lesions in the brain. However, moderate alcohol intake wa...ons, and brain atrophy. Infarcts and white matter lesions increase stroke risk. The researchers randomly selected 2,821 participants, 55 years or older, fro...'Sunshine vitamin' shines in colon study
...r part of the colon--missed a third of the serious lesions detected by colonoscopy....Medication provides effective treatment for moderate to severe psoriasis
...mpromised. For example, the physical appearance of lesions can cause patients to experience stress and embarrassment and have adverse effects on emotional aspects and normal functioning. Limitations of currently available psoriasis therapies highlight the need for effective and safe treatment options. Tradit...Drug-coated stents effective in 'real world' patients
...," Serruys said. "The effect was the same in long lesions and short lesions, in small vessels, and in all kinds of anatomic settings." The study included 508 patients with previously untreated blocked arteries who were treated with sirolimus-eluting Cypher stents. Four hundred fifty patients with similar ...Down syndrome study reveals possible method for detecting initial stages of Alzheimers
...enile plaques and neurofibrillary tangles, the two lesions associated with both Down syndrome and Alzheimer's. When the damaged neurons are ultimately destroyed by these lesions, the metabolic rate will decrease, as was observed in the Alzheimer's-diseased brains scanned for the study. "These findings sugges...Dr. Brenda Milner first foreign associate of the NAS to receive Award in the Neurosciences
...time. Her delineation of memory dysfunction after lesions of the hippocampus has provided the basis for modern understanding of memory and for the divisions of memory storage mechanisms into explicit and implicit forms", said Dr. Eric Kandel, University Professor in the Center for Neurobiology and Behavior ...C-reactive protein more than a heart disease marker
... form of C-reactive protein, they developed larger lesions associated with the buildup of fatty plaque in the arteries than did those who did not produce the protein. "Our study supports the use of C-reactive protein as a marker of risk for heart disease," said Chan. "Not only that, but it identifies at le...Some people with migraines have an increased risk for brain lesions
...perience migraines may be at an increased risk for lesions in certain areas of the brain, according to a stud...prevalence of cerebral infarction and white matter lesions (WMLs) is present in migraine patients. Infarction involves tissue which has died due to lack of oxy...Incidental PET findings may reveal undetected cancer
...ter's PET center. "Approximately 71 percent of the lesions that were confirmed with biopsy were either malign...e PET can frequently identify metabolically active lesions that may not be easily identified as anatomic abnormalities on CT. Abnormal findings on a PET scan c...OHSU researchers hope to prevent childhood asthma with new eczema drug
...curring skin disease characterized by red, crusted lesions on the face, scalp and extremities, and by oozing, crusting, extremely itchy broken skin. Some 10 percent of infants develop eczema and it persists in roughly 15 million adults and children, according to a study conducted at OHSU in 2000. For the ...