Researchers search for first sign of congestive heart failure
...o congestive heart failure, a disabling, sometimes lethal condition affecting nearly 5 million Americans. "What we are saying is that long before the pumping chamber of the heart becomes enlarged and dysfunctional a classic sign of congestive heart failure you have early changes in the way the heart is fu...Benefits of lung cancer screening with CT questioned
...w-growing tumors that probably would not have been lethal over the patient's lifetime. "While there is still reason to hope that early detection of lung cancer with CT may save lives, our results lead us to be very cautious, because there's a chance that we may be doing more harm than good," Dr. Swensen sai...Targeting mutant B-Raf protein reduces melanoma development
...f skin cancer, melanoma is the most metastatic and lethal form. It is currently the seventh most common cancer in the U.S., with about 52,000 cases diagnosed annually. Furthermore, it is the cancer with the second fastest growth rate. In 2004, an American's lifetime risk of developing melanoma was one in 63...Student identifies electrical changes preceding heart failure
...n spur a second, later phase of changes that cause lethal heart rhythm disturbances known as arrhythmias. T...rcent are sudden and unexpected, and the result of lethal arrhythmias." For their study, Hahn and Akar isolated small samples of heart tissue about the size o...Diagnosis of prions in patients should utilize novel strategy, team says
...diagnostic procedures currently used to detect the lethal particles in samples of brain tissue from patients, according to a study performed by a UCSF team. The finding indicates that the diagnostic technique, known as the conformation-dependent immunoassay (CDI), should be established as the standard appro...HIV patients may be at risk of heart problems when taking protease inhibitor drugs
...gressing to AIDS may cause serious and potentially lethal heart rhythm disturbances in some patients. The finding of a Mayo Clinic-led investigation appears in the current edition of The Lancet ( http://www.thelancet.com/home ). In collaboration with colleagues from the HIV Program of Hennepin County Medica...Carrot component reduces cancer risk
...lcarinol is toxic in large amounts but to obtain a lethal dose you would have to eat 400 kilograms of carrots at once. Researchers suspect it is effective because it stimulates mechanisms in the body that fight cancer, although they have yet to carry out a detailed analysis in this respect....American Thoracic Society Journal news tips for February 2005 (first issue)
...cross-infection still continued. (CF, an inherited lethal disease, causes certain glands to produce abnormal secretions that primarily affect the lungs and digestive tract. CF patients are especially susceptible to the gram-negative bacteria, P. aeruginosa, which has the potential to cause severe and possi...Phobic anxiety increases heart disease death risk among women
...onset of symptoms and is usually associated with a lethal rhythm disturbance. "Since these studies have been done in men, we decided that we would look to see if there was a similar relationship in women," said the study's lead author Christine M. Albert, M.D., M.P.H., assistant professor at Harvard Medical...New test is first step in early detection of Alzheimer's disease
...o has been used to detect trace amounts of anthrax lethal factor and prostate specific antigen (PSA), could be used to target known biomarkers for a wide variety of diseases, such as HIV infection, various cancers and Creutzfeldt-Jakob disease, enabling early diagnosis that would be impossible with conventi...Scientists identify protein critical to melanoma growth
...iscovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without. The findings, which are published in the December issue of Cancer Cell , suggest that drugs that cut off melanoma cells' supply of the protein, called CD...First US SARS vaccine trial opens at NIH
... our ability to battle these ever-evolving, highly lethal microbes," says Dr. Nabel. Under a contract with NIAID, Vical Inc. of San Diego, CA, is producing the SARS vaccine for the NIAID clinical trial. For more information on the SARS vaccine trial, phone the Vaccine Research Center's toll free number 1-86...Book celebrates centenary of city's advances in public health
...r housing and economic conditions in the city. The lethal epidemics of cholera and typhus disappeared sooner from Edinburgh than from any other large city in the UK, but other health and social problems like diphtheria, tetanus, polio and malnutrition of children, remained. Edinburgh pioneered many advances...Study finds HER2-positive breast cancer invades organs due to fatal chemical attraction
...n the November issue of Cancer Cell , describes a lethal attraction between signals found on HER2-positive breast cancer cells and those on the surface of the organs -a magnetism that explains why this form of breast cancer, which affects up to 30 percent of patients, can be so invasive. The vast majority ...News tips for Sunday, November 7, 2004
...often caused by silent cardiac disorders eliciting lethal arrhythmias. But many such deaths in young people go unexplained, because there was no prior history and no definitive post-mortem analysis. A study of 43 families of sudden unexplained death (SUD) victims who had died at or before age 40 found an ...New hope for ALS seen with genetic techniques, growth factors
...onment safe for neurons, and that they may mount a lethal inflammatory response against the neurons. In other work, scientists at the Swiss Federal Institute of Technology of Lausanne (EPFL) tackled a different genetic approach against the familial form of ALS that targets the SOD1 gene. Patrick Aebischer,...Promise of stem cells amplified
...e so migratory," says Snyder. "They are inevitably lethal because they can evade even the most extensive sur...dous tumor cells. The scientists studied the most lethal type of brain cancer: intracranial glioblastomas. Adult mice with the tumors received transplants of...Getting the fluid balance right in malaria
...or contributor to the pathology of this frequently lethal disease," says Nick White (Mahidol University, Thailand), who was not involved in the study. Until now, research efforts have been hampered because scientists did not have an easy way to assess the amount of fluid depletion in the body; ideally, scie...Ephedrine and unheralded sudden cardiac death
...s a blockage, boom, ephedrine causes a potentially lethal arrhythmia," Dr. Adamson said. "The heart starts beating so fast, it can no longer pump blood." Dr. Adamson used an animal model of ischemic heart disease. Of the 15 animals given ephedrine, nine had increased ventricular arrhythmias (a dangerous and...International MRC trial finds a routine treatment for head injury may do more harm than good
... could reduce deaths by preventing the potentially lethal brain swelling that occurs after head injury. But these studies were too small to be able to provide definitive evidence of benefit. The MRC CRASH* trial was specifically designed to answer this question and with over ten thousand patients recruit...