2005 Pulp Biology Research Award
... a cell adhesion molecule for nerve fibers closely linked to odontoblast cell membranes. Finally, revisiting the odontoblast morphology, he described the presence of a primary cilium in odontoblasts, leading to hypothesize that this structure could be involved in signal transduction. He is now investigating...Decreased levels of 'good' cholesterol in children with Progeria may cause premature heart disease
... regulates the metabolism of fat and sugar, may be linked to the disease process and prove helpful in finding treatments. Progeria is a rare, fatal genetic condition characterized by the appearance of accelerated aging in children, and affects about one in 4-8 million newborns. Although they are born loo...News tips from the 2005, 54th Annual Scientific Sessions of the American College of Cardiology
...isrupted fat cell signaling in obese mice has been linked to increased cell death, or apoptosis, in enlarged hearts. According to the Johns Hopkins researchers who led the study, the research is needed to understand how obesity contributes to enlarged hearts (hypertrophy), subsequent heart failure and incr...Cigarette smoke worsens respiratory infections in infants
... than Caucasian children. Because RSV infection is linked to childhood asthma and because African-Americans ...tes and cockroach allergen, all of which have been linked to allergy and asthma problems in older children and adults. "We were thinking that the kids who cam...Laughter helps blood vessels function better
...ore have shown for the first time that laughter is linked to healthy function of blood vessels. Laughter appears to cause the tissue that forms the inner lining of blood vessels, the endothelium, to dilate or expand in order to increase blood flow. When the same group of study volunteers was shown a...Researchers discover link between insulin and Alzheimer's
... in the brain, and that reduced levels of both are linked to Alzheimer's disease. The findings are reported in the March issue of the Journal of Alzheimer's Disease ( http://www.j-alz.com ), published by IOS Press. "What we found is that insulin is not just produced in the pancreas, but also in the brain. A...Study says rare allergic reactions to drug-eluting stents may raise risk for heart attack
...ensitive reactions to SES to see whether they were linked to major adverse cardiovascular outcomes." Dr. Alameddine, lead author of the research presented at a poster session today, notes that hypersensitivity to SES could be caused by the stent's metal, polymer, or sirolimus. In order to evaluate whether ...Studies underscore genetic involvement in nicotine addiction & aggressive hostility
...H (tryptophan hydroxylase), a marker that might be linked to another yet unknown gene with specific and functional aspects. Says Hennig, "Linkage means that both genes are transmitted together due to their being close neighbors on the same chromosome." The researchers measured genotypes dubbed AA, AC and C...Depression predicts heart rhythm abnormalities in heart attack patients
... tachycardia, it is known that depression has been linked to activation of the immune system, as well as alt...rties of blood platelets. Depression has also been linked to other such cardiovascular risk factors as insulin resistance, hypertension, obesity, increased ci...UCSD-Utah team develops mouse model to test therapies for macular degeneration
...s follows. Noting that scientists have recently linked mutations in a gene called ELOVL4 to AMD and STGD, the UCSD-Utah investigators developed mice with a mutant form of ELOVL4, which caused the mice to develop significant lipofuscin accumulation and photoreceptor and RPE death in a pattern closely rese...A shallow hip socket predicts osteoarthritis of the hip
...dislocation. Severe acetabular dysplasia has been linked to premature hip OA. The influence of moderate acetabular dysplasia on the development of hip OA is less clear. To assess the role of moderate acetabular dysplasia in the onset of hip OA, a research te...Daily supplement may boost birthweight of babies in the developing world
...every year. Maternal nutritional status is closely linked with foetal weight. Increases in macronutrient consumption during pregnancy can lead to increased birthweight. David Osrin (Institute of Child Health, UK) and colleagues did a trial to test whether multiple micronutrient supplementation at one recom...Both inherited traits and tumor mutations affect response to treatment of leukemia
...the success or failure of chemotherapy for ALL was linked to any of 16 common genetic polymorphisms in genes...ed 16 polymorphisms, including GSTM1 and TYMS were linked to risk of failure in the lower-risk group. The researchers concluded that GSTM1 and TYMS, are like...Fewer false alarms when mammographers have greater experience screening healthy breasts
... collect mammographic interpretations. Researchers linked the interpretation data to cancer registries and then to physician information from the American Medical Association. They studied 209 physicians who interpreted 1.2 million mammograms from January 1, 1995 through December 31, 2000 including 7143 tha...LA BioMed medical/research briefs March 2005
...ge increase of fatty liver disease, which has been linked to insulin resistance; PCOS has also been linked to insulin resistance. The study noted that PCOS is the most common form of non-ovulating infertilit...Elderly receiving inappropriate prescriptions from their doctor's office
New York, NY - A large review of data linked to over 175,000 older adults enrolled in HMOs indicates that potentially inappropriate medications are being prescribed in substantial numbers. The findings are published in the February Journal of the American Geriatrics Society . In 2000-01, acco...Researchers model brain's electrical storm during a seizure
...efore spreading out, and others, particularly ones linked to genetic causes, appear to start simultaneously in various parts of the brain. What is clear is that during a seizure, a strong pattern of electrical signals suddenly emerges from the random fluctuations that characterize normal brain activity. Th...When the brain, not the ears, goes hard of hearing
...o contribute to congenital deafness, none has been linked to age-related hearing loss in humans. The latest studies offer several promising leads in genes that affect the functioning of brain chemicals like glutamate and GABA, important neurotransmitters that allow nerve cells in the ear and brain to talk t...Physical activity linked to protection from Parkinson's disease
...renuous activity in the early adult years was also linked to a lower risk of Parkinson's, but this relationship was not statistically significant, and there was no clear relationship between physical activity later in life and Parkinson's risk. To examine the relationship between physical activity and Parki...Slow growth in infancy signals poor economic prospects in adulthood
...mes during the first year of life. The researchers linked these measurements to their educational levels and information on income and occupation, taken from the 1990 census. The analysis showed that boys who were taller between birth and 1 year earned more than their shorter peers, irrespective of family b...