Optical technique identifies vulnerable plaques in cardiac patients
...fats), a thin cap of fibrous material covering the lipid pool, and infiltration of the immune cells called ...ed that the heart attack and ACS patients had more lipid in their plaques and significantly thinner fibrous caps than did the stable angina patients. Overal...New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS
...C) is made of dead cells that contain proteins and lipid molecules which are arranged in bi-layers. The SC ...ipids. Others insert themselves in already-crowded lipid bi-layers to disorganize them. Some can also break open the dead cells in the SC and interact with t...Obesity among African-American stroke survivors increases risk factors for recurrent stroke
...on, dyslipidemia (high cholesterol levels or other lipid level problems), stroke, coronary artery disease and decreased life expectancy. Sean Ruland, D.O., of the University of Illinois at Chicago, and colleagues analyzed data from African-American patients enrolled in a study of treatment for prevention ...Meditation may reduce heart disease risk
...s. "We know this type of change is achievable with lipid lowering drugs, but it's remarkable that a meditation program can produce such a change," the researcher says. In the April 2004 issue of the American Journal of Hypertension, Dr. Barnes and his colleagues reported that 15 minutes of twice-daily tran...'Marital strain' increases women's risk of death, heart disease
...and had higher blood pressure and a less favorable lipid profile compared to unmarried men," Eaker said. "Unmarried men were more likely to be smokers." After the researchers made statistical adjustments for age, systolic blood pressure, body mass index, cigarette smoking, diabetes, and the ratio of tota...Small increases or 'blips' in HIV levels do not signal mutations leading to drug-resistant HIV
...f medications can have toxic side effects, such as lipid abnormalities and diabetes, and can be considerably harder to tolerate than the originally prescribed drug cocktail. Today's anti-HIV drug treatments quickly suppress the virus to nearly undetectable levels, but blips are a frequent problem. Earlie...Cholesterol under-treated in high-risk women in managed care study
...rther evidence for a need to improve comprehensive lipid management in the highest-risk women, Mosca said. "These findings suggest that therapies should be targeted to the specific cholesterol abnormalities in each woman, so that optimal levels of both the good and the bad cholesterol can be attained," Mos...Type of weight loss surgery more effective at reducing insulin resistance
...ersion was exploited to highlight the link between lipid malabsorption and insulin action. However, the choice of the optimal therapeutic strategy in these patients depends on a risk/benefit algorithm to be assessed in each patient."...Tip sheet Annals of Internal Medicine, Jan. 18, 2005
...n, with beneficial lifestyle changes, improved all lipid profiles, the study does not show whether the increased HDL levels or the decreased LDL levels led to the changes in artery disease....Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
...vels. "These studies confirm the value of lipid lowering for patients with coronary heart disease and suggest that therapy targeted to reduce the active inflammatory state may carry additional benefits," he said. Dr. Michael R. Ehrenstein and colleagues in the department of medicine at...McGill researchers identify new way to reduce cholesterol levels
...nued for eight weeks, blood samples were taken and lipid analysis was performed. "In comparison with plant ...neficial change in the volunteer's cholesterol and lipid levels," said lead author and McGill doctoral student, Krista Varady. "This combination therapy favo...Prevalence of nonalcoholic fatty liver disease varies by ethnicity
... suggest that there are fundamental differences in lipid homeostasis among ethnic groups. The authors found that while blacks and Hispanics had similar levels of obesity and insulin resistance, blacks had a much lower prevalence of hepatic steatosis. They also found further evidence that a normal serum ALT...Endocrine Society calls for clinical guidelines on androgens for women
...ns include hematocrit or hemoglobin determination, lipid measurement, yearly mammography and endometrial ultrasound. Some experts also suggest that free testosterone should be measured before treatment and monitored during treatment. Testosterone therapy has been studied previously in different groups of...New drug protects against the hardening of arteries
...ma (known as PPAR agonists) are used to treat high lipid levels (such as cholesterol and triglycerides), an... mechanism described by Li and colleagues by which lipid accumulation is reduced by these agonists, thereby giving us a greater understanding of the roles of...Marine sponge leads researchers to immune system regulator
...e , the researchers provide evidence that a sugary lipid known as iGb3 plays a key role in regulating the r...ates, rather than proteins. When presented with a lipid that may signal a threat, they pump out chemical signals, such interferon-gamma and interleukin-4, w...Optimism associated with lowered risk of dying from heart disease
...ical activity, obesity, smoking, hypertension, and lipid profile, pessimistic subjects may be more prone to changes across time in risk factors that affect the progression of cardiovascular disease (e.g., the development of smoking habits, obesity, or hypertension) than optimistic subjects. Dispositional ...Location of body fat important in predicting heart attack risk
...nt of body fat, diabetes, blood pressure and blood lipid levels." One surprising finding from the study was that intra-abdominal fat was not a predictor of heart attack in men ages 70 to 79. "None of the body fat measures were predictors of heart attack in men," said Nicklas. "My theory is that men who ha...Outstanding efficacy of Crestor (TM) in treating range of patient populations at risk of CVD
...t CRESTOR is superior to atorvastatin in improving lipid profiles associated with an increased cardiovascular risk in a number of patient populations with dyslipidaemia. 1-5 Results from MERCURY I and DISCOVERY also show that CRESTOR, at the usual start dose of 10mg, enables more patients achieve their U...MRI can measure early benefits of cholesterol-lowering drugs and plaque reduction
... therapy are due to their abilities to lower blood lipid levels or if they were merely the short-term effec...found was that LDL cholesterol levels, a key blood lipid indicator to lower in treating heart disease, were lowest in patients with the greatest amount of pl...CRESTOR leads in 1st international prospective study of statins in the metabolic syndrome
...sk' patients, lowering LDL-C levels is the primary lipid treatment target to reduce their cardiovascular ri...ve than atorvastatin 10mg at improving the overall lipid profile associated with heart disease risk. Commenting on the results, Professor Schuster of Humbo...