Tag: "livers" at medical news

Shark-Liver Substance May Slow Growth Of Brain Tumors

...ine may work against brain cancer. Squalus sharks' livers produce an oil used in manufacturing drugs, and small amounts of squalamine are found in shark cartilage. Squalamine dramatically slowed blood vessel cell growth without damaging healthy cells, according to Henry Brem, M.D., co-author of the studies ...

Far Few Drugs Are Tested On Children

...ot realise until too late that children's immature livers wereincapable of clearing it from their bodies, and toxic levels quickly built up intheir bloodstream. Astonishingly, children still face similar risks today. The vastmajority of drugs have never been tested on children, forcing doctors topre...

Trial Begins For First Artificial Liver Device Using Human Cells

...tudies, nearly two thirds of acetaminophen-damaged livers haverecovered without transplantation. The seconda...for a liver transplant and fewer than 4,500 viable livers donated eachyear, there is no guarantee that a suitable organ will become available in time.In 1997,...

Researchers At Cedars-Sinai Medical Center Develop Method To Detect A Deadly Complication Of Pediatric Transplantation

...t affects 10 to 15 percent of children who receive livers orother donated organs can now be detected and treated early. Using a method of periodic testing devised by researchers at Cedars-SinaiMedical Center, physicians can monitor the progress of young transplantrecipients to rapidly detect virally infect...

Livers From Children Are Going To Adults, University Of Pittsburgh Review Of National Data Reveals

...ults CHICAGO, May 17 -- Nearly two-thirds of all livers donated by children since1991 were transplanted in...d in the United Statesshows. With fewer of these livers available for children, surgeons have been forced tolook at alternative options, such as those invol...

Whole-organ pancreas transplants and partial liver transplant programs arepriorities for renowned transplant surgeon at Cedars-Sinai

...itional risk to the patient." Because the need for livers and kidneys is rising much more quickly than thenumber of organs becoming available, Dr. Shackleton and his colleagues willcontinue to employ the latest procedures to make the best use of cadaver organsand those provided by living donors. "If we look...

Artificial liver moves toward commercialization

... Improving device performance: Artificial livers currently being tested employ straight-line hollow fiber bioreactors to house the chemical-processing cells that substitute for the human liver. Such devices are subject to clogging and transport difficulties, resulting in poor transport of n...

Humans can regrow liver from bone marrow

...ve hepatocytes and cholangiocytes. Thus the female livers regenerated tissue from male cells -- "most likely...chemical detoxification, bile-producing artificial livers need a living component to replace the damaged organ completely. "Liver cells, ironically, are hard ...

Aerosol form of cyclosporine hits key cellular target in lung transplant patients, researchers report at international meetin

...alermo and the UPMC. Since last year, more than 18 livers and 13 living-related kidney transplants have been performed there....

Enzyme could provide continual fat burning

...rly one-half the fat of the normal mice. The fatty livers of normal mice looked pale compared to the bright red, virtually fat-free livers of the genetically engineered animals. In one study, the researchers gave the ACC2-deficient mice i...

Artificial organs

...is doesn't work for the thicker tissues typical of livers and kidneys because nutrients can only diffuse across a few cell layers. Instead, they need an internal blood supply to deliver nutrients to cells deep inside the organ. "Without a blood supply, the tissue dies," says Borenstein, a micro-engineering ...

Glutathione depletion in chronic alcohol abuse makes lungs vulnerable to life-threatening diseases

... alcohol abusers as alcohol itself can be to their livers and other organs, says David Guidot, M.D., associate professor of medicine at Emory University School of Medicine. Dr. Guidot will explain how glutathione depletion affects the lungs at a symposium on the cellular effects of chronic alcohol abuse at...

New treatment reduces liver tumors and improves quality of life for cancer patients

...nd is fairly well tolerated even in patients whose livers are highly susceptible to radiation-induced damage...body because they are too large to fit through the livers capillary system. HCC kills up to a half million people around the world each year, primarily in Afr...

Artificial liver trials show progress, as transplant candidates wait

...lled status 1 -- at the top of the list to receive livers as they become available. But that means patients ... they are detached and stored. But in people whose livers are failing, the toxins stay in the blood and can harm nerve function, increase pressure in the brai...

UNC among 10 U.S. medical centers tapped to study living donor liver transplants

...this procedure with those for patients who receive livers from cadavers. Because of the shortage of donor l...world are trying to expand the donor pool by using livers from live donors. UNC has been a pioneer in this effort," said Dr. Roshan Shrestha, associate profes...

Organ transplant recipients face serious kidney-failure risk, study finds

...et a second chance at life from new hearts, lungs, livers or intestines are very likely to have their lives cut short by failing kidneys. In fact, 16.5 percent of all non-kidney transplant recipients develop chronic kidney failure, and almost a third of those patients go on to develop full-blown end-stage ...

Fosrenol shows significant reduction in serum phosphate in Chinese end-stage kidney disease patients

...stopathological changes were seen in the brains or livers of lanthanum carbonate-treated animals, and there was no significant penetration of lanthanum carbonate into the brain. Similarly, neurobehavioral screens in mice or dogs receiving lanthanum carbonate for up to 62 weeks were normal. Managing Hyper...

Donor livers not consistently allocated according to medical need

A new study suggests that donor livers are not always distributed according to a patient'...t likely explanation for this disparity is that DD livers are preferentially retained for transplantation in the local OPO, where the number of patients with ...

Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients

...subfulminant hepatic failure and 24 patients whose livers had failed after transplantation. Of the 171 total patients, 85 received BAL treatment, while 86 received standard supportive care. For the entire patient population, survival at 30 days was 71 percent among the BAL group, compared with 62 percent f...

Cutting-edge science offers improved care for liver diseases

...umbilical cord blood cells (UCB) to repair damaged livers in recipient mice. UCB cells have many advantages as a source of stem cell transplantation because of the immaturity of newborn cells compared with adult cells. To identify the benefit, the team collected UCB samples from full-term human deliveries...

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