JCI table of contents, January 20 2005
...pathway that jumpstarts the autoimmune response in lupus Patients with systemic lupus erythematosus (SLE) produce autoantibodies to their own proteins and DNA and the resultant inflammat...Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
...ive disorders to rheumatoid arthritis and systemic lupus erythematosus," they wrote....Chemical cousin of anti-anxiety drugs holds promise for psoriasis treatment
...uce harmful side effects of the autoimmune disease lupus also may be useful in treating psoriasis. In a study published online Dec. 3 in the Journal of Pharmacology and Experimental Therapeutics, scientists from the University of Michigan report that a compound called benzodiazepine-423 (Bz-423)---a chemic...Pitt researchers identify biomarkers of lupus which could lead to quicker and better diagnosis
...in earlier and more accurate diagnosis of systemic lupus erythematosus (SLE), a devastating disease that af...ning multiorgan failure, and the manifestations of lupus often mimic those of other diseases makes it difficult to diagnose." It is not unusual for a p...Symposium highlights new emerging therapies for the treatment of lupus
...ely 1.4 million Americans have been diagnosed with lupus Women are 8-10 times more likely to suffer from lupus than men Lupus occurs primarily in women in their childbearing years Lupus is 3 times more common ...The protective effects of heparin in preventing miscarriages in lupus patients
...tic pathway for preventing miscarriages in certain lupus patients. Their research on the recurrent pregnancy loss that afflicts systemic lupus erythematosus patients was published in the October 17, 2004, online edition of Nature Medicine. The...Mayo Clinic finds effective treatment with minimal side effects for non-renal lupus
...til is effective for managing symptoms of systemic lupus erythematosus (SLE), the most common type of lupus...etil has been shown to be helpful in patients with lupus affecting the kidneys. The new Mayo Clinic research indicates, however, that the drug could help ma...NIH launches study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus
...patients with severe, treatment-resistant systemic lupus erythematosus (or lupus), a rheumatic autoimmune d...te blood cells in the immune system, in triggering lupus symptoms. In this pilot study, 14 patients from ages 15 to 40 will receive stem cell transplantation...Two-way link between heart disease and autoimmunity
...toimmune diseases such as rheumatoid arthritis and lupus are associated with an increased risk of atherosclerosis and heart disease, which is the leading cause of death in the developed world. A new mouse model, reported by Kenneth Walsh and colleagues in The Journal of Experimental Medicine, now shows tha...Lupus discovery may pave way to better-designed COX-2 inhibitors
In an important development in the treatment of lupus as well as certain cancers, scientists at the Fein...hwestern University have discovered how autoimmune lupus T cells stave off programmed cell death and drive production of autoantibodies directed against the ...Rare disease endemic in South America is model for studying autoimmunity
... itself. Type 1 diabetes, rheumatoid arthritis and lupus are familiar autoimmune diseases; but it's the rar...diseases, including Senear-Usher, a combination of lupus and pemphigus found sporadically across the United States. The El Bagre disease has much in common w...Arteries clog earlier in people with lupus, says new study
People with the autoimmune disease lupus may develop carotid atherosclerosis (the buildup o...Y.), and their colleagues examined 197 people with lupus and the same number of matched controls. Risk factors for cardiovascular disease, including family h...JCI Table of Contents, November 14, 2003
...c CD154 antibody shows utility in the treatment of lupus Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the production of pathogenic a...Regeneration of insulin-producing islets may lead to diabetes cure
...d be applied to other autoimmune diseases, such as lupus and Crohn's disease two disorders believed by many to be caused by a similar disruption of the same immune process her team originally identified in diabetes. Her work has largely been supported by grants from the Iacocca Foundation, founded by Lee ...Autoantibodies precede disease in lupus patients
...NIAMS) reveals that people diagnosed with systemic lupus erythematosus (lupus) -- an autoimmune disease in ...bodies in their blood years before the symptoms of lupus appear. The early detection of autoantibodies -- proteins that attach to the body's healthy tissues ...Standard treatment for rare form of deafness no more effective than placebo
...ow-dose methotrexate, a drug that is used to treat lupus and other disorders, for managing hearing loss in autoimmune inner ear disease (AIED), a progressive disease caused by antibodies or immune cells damaging the inner ear. The hearing loss occurs over a few months and is often accompanied by ringing, ...NIH awards $51 million to fight autoimmune diseases
...y distinct autoimmune diseases, including systemic lupus erythematosus, type 1 diabetes, severe lupus nephritis, Sjogren's syndrome and multiple sclerosis. Those suffering with autoimmune diseases often...New study aims to prevent heart disease in pediatric lupus patients
...o prevent heart disease in pediatric patients with lupus erythematosus. Atherosclerosis, or hardening of th...ng children with lupus. Atherosclerosis puts young lupus patients at high risk for cardiac problems including heart attack or stroke. According to recent res...Lupus Today: Research into Action
WHAT: National leaders in lupus research will gather todiscuss the latest scientif...upus. Panel discussions will include:the future of lupus clinical trials, patient participationin clinical trials, and how lupus affects specialpopulations. ...Pitt transplant researchers say anti-rejection drug rapamycin may help lupus, some cancers
... organ rejection, could also benefit patients with lupus and other autoimmune diseases as well as patients ...s inhibitory action on dendritic cells is systemic lupus erythematosus because dendritic cells accumulate in lupus lesions and are thought to drive the immun...