Kadian alleviated chronic pain in patients unsuccessfully treated with well-known therapies
...e pre-study OxyContin patients. All patients were maintained on Kadian therapy within the recommended QD or Q12h dosing specified by the prescribing information. Quality of Life (QoL) Measurements Showed Marked Improvement Researchers, including Dr. Weil, also examined the ability of Kadian to alleviate pain...Missing signal causes misrouting in certain degenerative eye diseases
...gh levels of long-chain fatty acids, which must be maintained if the retina is to remain healthy. "Our current research suggests that the gene is involved in the metabolism of these fatty acids, but we don't know exactly how," says Ayyagari." She plans further research aimed at learning more about the biolog...Oxygen therapy may improve vision worsened by diabetes
... normal range while on oxygen, the improvement was maintained even after oxygen was stopped. Since these patients all had previous laser therapy, it is possible that the reduced thickening of the macula achieved by oxygen allowed the laser to exercise a stabilizing effect. Diabetic macular edema affects up to ...Kidney cancer surgery safer at high-volume hospitals
...nt of all hospital discharges in the United States maintained by the Agency for Health Care Research and Quality. Patients underwent radical nephrectomy (complete removal of the kidney), nephroureterectomy (removal of the kidney and ureter) or partial nephrectomy. The participating hospitals were classified acc...Study: Low-carb diet more effective than low-fat diet
...ncipal investigator for the study. The researchers maintained exclusive control of all data and analyses....Elan and Biogen Idec announce results from Phase III maintenance trial of Antegren
...hase III maintenance study, ANTEGREN (natalizumab) maintained clinical response and remission rates throughout six months among patients with Crohn's disease (CD) who had previously achieved clinical response. Additionally, a majority of natalizumab-treated patients who were also on chronic corticosteroid ther...Breakthrough therapies treat Crohn's disease
...esearchers observed the proportion of subjects who maintained the response they had achieved in ENACT-1 for an a...n the placebo group. Also, 44 percent of patients maintained clinical remission, compared with 26 percent on placebo. In addition, 55 percent (37/67) of nataliz...New data supports CellCept's position as a world leader in solid organ transplantation
... on existing five-year data. In addition, CellCept maintained normal creatinine levels an indicator of healthy kidney function for twice as long as the AZA group (14.5 years versus 6 years). in allograft dysfunction in adult patients Two further studies reinforced CellCept's position as central to a safe,...Weekly cycles of once-daily anti-HIV drugs could reduce cost of HIV treatment
...the other seven patients receiving the 7-7 regimen maintained undetectable levels of HIV in their bloodstream [<50 HIV RNA copies per milliliter] for 60 to 84 weeks. During this period, the study volunteers had no significant changes in their CD4+ T-cell counts, and no evidence of resistance to the antiretr...VELCADE(TM) data confirms long-term survival
...served. Importantly, statistical significance was maintained even though approximately 50 percent of patients crossed over to receive VELCADE TM after experiencing progressive disease on the dexamethasone arm; During the first year, there was an estimated 30 percent reduction in risk of death in patients rec...4 out of 5 eligible patients missing opportunity to benefit from latest HIV breakthrough
...Comprehensive FUZEON benefits seen by 3 months and maintained at 2 years Dramatic FUZEON virological benefits c...FUZEON. Furthermore, data show these benefits are maintained at 2 years. FUZEON patients also reported approximately half the incidence of diarrhoea, a common an...Different subgroups of alcoholics respond differently to serotonin-acting medication
...ix months following treatment, Type A alcoholics maintained their gains, whereas Type B alcoholics who had tak... been treated with sertraline instead of a placebo maintained for at least six months after treatment had ceased the positive results they had obtained during t...FDA approves Adderall XR (R) to treat ADHD in adults
...toms at week one, the first evaluation period, and maintained this significant improvement throughout the four-w...onstrated that significant symptom improvement was maintained over 18 months. The most frequently seen side effects of ADDERALL XR in the adult clinical trial i...New data show SPIRIVA significantly reduces COPD exacerbations and related health resource burden
... a current first-line therapy for COPD, which were maintained over one year.10,11 In addition, in one-year, placebo-controlled studies, patients treated with SPIRIVA required fewer doses of rescue medications. 12 In clinical trials, the most common adverse reaction reported with SPIRIVA was dry mouth, which wa...Generation gap widened in social spending for elders compared to children
...elderly. In addition, federal budget policies have maintained guarantees of support for the elderly, while social welfare programs for children have devolved to state governments, where funding is less stable. "Despite the economic expansion of the 1990s and persistent socioeconomic health disparities, the gap ...Revolutionary HIV drug Fuzeon wins most prestigious award for innovation
...thermore, data now show that these benefits can be maintained for two years," commented Dr Anton Pozniak, Consultant Physician, Department of HIV and Genitourinary, Chelsea and Westminster Hospital, UK. International Prix Galien Award The International Prix Galien award recognises significant advances in pha...Switch of a gene turns cancer cells healthy in mice, Stanford scientists find
... The mice remained cancer-free as long as they maintained their diet of the antibiotic. But as soon as Felsher withheld the doxycycline, the gene was back on; Myc protein accumulated in the liver cells, and theanimals developed aggressive liver cancer within an average of 12 weeks. Returning these can...Slightly increased risk of Ischemic stroke found with tamoxifen
... since 1980 using the biomedical database MEDLINE, maintained by the National Library of Medicine. Their aim was to determine the overall risk of both ischemic stroke and all strokes associated with taking tamoxifen. Nine trials met their inclusion criteria, with 39,601 total subjects enrolled, 19,954 of whom w...FDA approves Fosrenol(R) in end-stage renal disease (ESRD) patients
...FOSRENOL for up to four years showed that patients maintained healthy bone throughout the duration of treatment. 10 Matthew Emmens, Chief Executive of Shire commented: "The approval of FOSRENOL in the U.S. is another milestone for Shire. FOSRENOL provides a much-needed treatment for end-stage renal disease pa...Longterm immune memory cells cells do not develop during chronic viral infections
...of the viral antigen. The acute memory cells were maintained through homeostasis and divided several times, but...y phase of infection, HIV-specific CD8 T cells are maintained more efficiently. "Our research shows that prolonged exposure to antigen without any rest results i...