NCI scientists create model that predicts follicular lymphoma survival
...rtant interplay between the host immune system and malignant cells in follicular lymphoma. "One possibility is that the immune cells with the good-prognosis signature are attacking the lymphoma and keeping it in check," Staudt speculated. "Another possibility is that these immune cells may provide signals th...Computer program helps doctors diagnose lung cancer
...e, the borders and the shape to determine if it is malignant or just a benign growth. Researchers at the Univer... that will both detect a lesion and identify it as malignant or benign. In addition to Hadjiyski, researchers were Berkman Sahiner, Ph.D., associate professor of...Herpes virus offers new hope in curing cancer
...earchers have successfully treated the most common malignant abdominal tumor of childhood: neuroblastoma tumors. Researchers successfully treated the tumor in mouse models by administering a treatment based on a weakened version of the herpes simplex virus. The study appears in the current online issue of Pedi...Other highlights in the December 1 JNCI
...een associated with an increased risk of cutaneous malignant melanoma, but the molecular mechanism of the assoc...lanomas and in the cells of patients with familial malignant melanoma, but it is not known if the locus is involved in DNA repair. In a new study, Thomas M. Rnge...Magnetic resonance imaging helps detect breast cancer but does not eliminate need for biopsy
...nce imaging (MRI) distinguishes between benign and malignant breast tumors better than mammography, biopsies are still needed to confirm the diagnosis. The study, called the International Breast MR Consortium, was carried out in 14 university hospitals in the United States and Europe, including Johns Hopkins...Major step forwards for vaccine against cervical cancer
...al target for treatment because they only occur in malignant cells. The vaccine developed by Bungener, induces a specific immune response against these two proteins. To test the vaccine, Bungener administered two different vaccines to mice. The 'recombinant Semliki Forest virus' and virosomes from the flu vir...Scientists identify protein critical to melanoma growth
...nd Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without. The findings, which are published in the December issue of Cancer Cell , suggest that drugs that cut off melanoma cells'...Finding lymph node metastases in cancer
...were able to see different patterns for normal and malignant nodes. It was then possible to design a computer program that could recognize metastases. And then the program was able to produce a 3-D reconstruction of the lymph nodes which could possibly be used by oncologists and surgeons to provide optimal tre...Ethics of neuroimaging research to be focus of NIH/Stanford meeting
... a benign cyst, but could also be life-threatening malignant tumors or abnormalities in the blood vessels. Such results pose thorny problems that researchers must now consider. If, for instance, the benign tumor is added to the volunteer's medical record, it could alter health insurance rates - a fact research...Residual tumor cells are a barrier to targeted cancer therapeutics
...free. These residual cells quickly recovered their malignant properties either spontaneously or after the researchers reactivated MYC. Additionally, by sequentially turning the MYC gene on and off in these tumors in order to simulate the treatment of patients with multiple rounds of a molecularly targeted ther...Potential cure for lymphoma in HIV patients
...the University of Chicago notes, "The treatment of malignant lymphomas in HIV-infected individuals remains challenging, due to both the high incidence of refractory disease and the high risk of treatment-related complications. The ability of high dose chemotherapy as demonstrated in this pilot study to effecti...Mayo Clinic researchers report success in new molecular breast imaging technique
... molecular breast imaging: Twenty-six women had 36 malignant lesions confirmed at surgery. Molecular breast imaging detected 33 of the 36 lesions. In addition, four cancers were detected that were not seen on mammogram. Stephen Phillips, M.D., a Mayo Clinic radiologist involved in the study, said the technique...Vaginal hysterectomy leads to better outcomes than abdominal surgery
...lly been used when a woman has an enlarged uterus, malignant tumors or conditions such as endometriosis. The Cochrane researchers also reviewed the evidence comparing laparoscopic and abdominal hysterectomy. In laparoscopic hysterectomies, the uterus is removed with the help of specialized instruments and a sm...Sunlight reduces risk of lymph gland cancer
... 3,000 patients who were newly diagnosed as having malignant lymphoma, either non-Hodgkin's or Hodgkin's, between 1999 and 2002 in Sweden and Denmark, and just over 3,000 randomly chosen healthy members of the public. Participants were also asked about previous forms of diagnosed cancer. Mechanisms unclear I...Brain tumor treatment can vary greatly, according to new JAMA study
Primary malignant brain tumors are not very common about 9,000 patients diagnosed per year and are associated with a poor prognosis. Treatment of these patients varies greatly among academic and community centers and can be in conflict with accepted guidelines of ca...Other highlights in the February 2 JNCI
...besity is not associated with an increased risk of malignant lymphomas, according to a new study. The recent worldwide increases in both obesity and non-Hodgkin lymphoma have led some researchers to suggest that the former might explain the latter. However, studies seeking evidence that obesity might increase...Treatment for brain tumor does not always follow recommendations
...ntensive research, the prognosis for patients with malignant glioma remains poor. Typical survival for patients...de IV glioma). Current treatment for patients with malignant glioma includes maximum safe resection (surgical removal), radiation therapy, and chemotherapy. Susa...Inflammatory cells highly promising target in NF 1
...argets against a non-malignant cell than it is the malignant cell itself," said Dr. Clapp. That's because the b...ctivities of non-malignant cells are stable, while malignant cells are constantly changing due to the genetic instability common to tumors. By using drugs that t...New treatment rivals chemotherapy for lymphoma, U-M study finds
...e of the cancerous cells. The radiation zaps these malignant cells with minimal exposure to normal tissues. With the Bexxar therapeutic regimen, a patient receives an injected test dose of radioactive Bexxar to determine how that patient's body processes the tagged antibody. Nuclear medicine scans are used to ...Brain-scanning technologies need standards, according to Stanford researcher
...s a benign cyst but could also be life-threatening malignant tumors or abnormalities in the blood vessels. Each type of brain-imaging study poses its own quandaries. For example, should all brain studies have MDs on the research team? The volume and cost of having a physician read each and every scan would be ...