Study suggests potential new approach to glaucoma therapy
...ocular pressure. "As the paper reports, there were marked changes in the eyes of animals that didnot receive the drug," Neufeld said. "But we didn't seen that type of cell lossin animals that were treated with aminoguanidine. Statistically, the retinalganglion cell loss was not any different than in the con...100 years of Freud's interpretation of dreams
...nt of psychoanalysis. The book's publication also marked the real beginnings of scientific researchinto the mind and to the development of truer understanding of mental healthproblems. Because of its influence on scientific thinking, The Interpretation of Dreamshas led to everything from drug treatments f...Hard liquor, not beer or wine, may explain trends in cirrhosis mortality
...drop in spirits consumption was soon followed by a marked dip incirrhosis mortality but the 1946-47 drop was not. Measurement problemsassociated with wartime and immediate post-war consumer behavior, includinghoarding of scarce goods, make these tests suggestive rather than definitive,said Roizen. "Our res......cessful role in psychiatricpharmaceutical research marked by the discovery and introduction of breakthroughtherapies such as the antipsychotic MellerilR (thioridazine) in the 1950's, andthe schizophrenia drug LeponexR/ClozarilR (clozapine) in the 1970s. Zomaril(iloperidone), a new antipsychotic currently ...'Silent stroke' linked to depression
...s. "Their depression may bemore characteristically marked by apathy, a loss of interest in their usualactivities, instead of sadness. So, as a result, neither the patients, theirfamilies nor their physician, may recognize these characteristics as signs ofclinical depression. Patients with risk factors for...Who should have heart bypass surgery? New guidelines will help doctors, patients decide together
...g common complications,says Eagle. The result is a marked improvement in post-operative survival, withmore than 80 percent of patients still alive 10 years after their operation. "Enough studies now exist that we can say with confidence that bypass not onlyincreases the length of life, but increases its qua...... for farm children as for the others. This clearly marked difference persisted when other factors were taken intoaccount, such as genetic background, parents' education, eating habits andliving conditions. In order to make quite sure and to refine his results, Josef Riedler tested howthe figures would look ...Lack of sleep alters hormones, metabolism
...ker of diabetes. The differences were particularly marked when tested in the mornings. "Undersleep debt conditions, our young lean subjects would have responded to a morningglucose tolerance test in a manner consistent with current diagnostic criteriafor impaired glucose tolerance," note the authors. Impa......o less than 50copies per milliliter of blood and a marked diminution of an important viralreservoir - the pool of latently infected, resting CD4+ T cells," says Dr. Chun. "But the question still remained whether levels of HIV would remain lowfollowing discontinuation of therapy." "The answer, unfortunately,...UI study shows classification system for evaluating childhood hip disease may be unreliable
...er skeletal maturity," Weinstein said. "There were marked inter-rater variances among the nine physicians regardless of their experience level." Weinstein said that the study results may be over-estimations of true reliability and that the reliability in actual clinical practice may be even lower. "The part...Research challenges conventional thinking on ways to treat prostate cancer
...t Herceptin® combined with Taxol® caused a marked regression of tumors in both androgen-dependent and independent disease. This work, conducted by Memorial Sloan-Kettering researchers, was published in the October 1 issue of Cancer Research. In addition, the investigators found that Herceptin® ...UK College of Medicine researchers develop novel technologies to study neural genes
...ed in circadian rhythms. But we're playing with a marked deck. When our cards are turned upside down now, the matching neurons, or the ones that share the function of being involved in circadian rhythms, are glowing bright green." McClintock's part of the research team is developing ways to identify larg...Hypertension drug effective at preventing atherosclerosis
... have high blood pressure. The monkeys, which have marked similarities to humans in the development of cardiovascular disease, were fed a high-fat diet that raised their cholesterol levels to about 300. From previous studies, the researchers knew that fatty streaks, the first sign of vessel disease, begin t...Drug-psychotherapy combo found highly effective in depression study
...Americans suffer from chronic forms of depression, marked by severely disabling psychological and social problems. Annually, more than 46 million Americans, ages 15-54, suffer from depressive episodes. Depression costs the US economy an estimated $53 billion each year. ...... presented at AGA showing that colonic tumor cells marked by hereditary defects different from the APC gene mutation that characterizes FAP also undergo apoptosis, or programmed cell death, when treated with Aptosyn. The company also reported laboratory findings that the cyclic GMP phosphodiesterase targete...Using PET scan technology to study alcohol's effects on the brain
...otransmitter." "We found that both drugs induced marked reductions in whole brain activity," said Volkow. "The reductions were most accentuated in the occipital cortex (visual area) and in the cerebellum (an area involved with motor control), which we believe is due to the fact that these areas have a ve...Missing proteins in the uterus tied to infertility in women with endometriosis
...around the time of embryo implantation. "We saw a marked reduction of implantations in the mice that received the fluid from the infertile women with endometriosis." Lessey said. "And when we looked at the level of utetrine beta3 integrin in the mice that got this peritoneal fluid, we noticed it was absent...Duke eye researchers describe cascade of events that may lead to retinal degeneration
..." progressing to blindness over many years. RP is marked by the gradual degeneration of the specialized photoreceptor cells that line the retina along the back of the eye. These cells, better known as rods and cones, translate light that enters the eye into nerve impulses that travel to the brain for inte...Cell transplants offer hope of brain repair following stroke
... and adult rats damaged by stroke. The cells were marked with a chemical that glows when viewed under a fluorescent microscope, allowing researchers to record their fate for 90 days. Because the growth of cells is often influenced by the surroundings, researchers grew the cells in different "cellular envi...Largest ever overactive bladder study published in leading urology journal
... million in the U.S. alone. Overactive bladder is marked by symptoms of frequent urination, and urgency with or without urge incontinence (wetting episodes). Overactive bladder is a disruptive but treatable condition that can be managed, said Philip Van Kerrebroeck, M.D., Ph.D., Chief, Department of Urolo...