The statin wars: Why AstraZeneca must retreat
...suvastatin, a drug launched into the global statin market last month on the basis of as yet incomplete resea...rch findings. The editorial comments: 'The statin market is vast. Pfizer's atorvastatin-the world's best-selling drug-had sales in 2002 of US$ 8 billion. Ast...Rochester chosen to focus on rare neurological diseases
...nts translates to financial loss because of a tiny market for a new drug. In addition, researchers must find collaborators around the globe to create a pool of patients large enough to do a valid study. Griggs has pulled together a nationwide CINCH team Clinical Investigation of Neurologic Channelopathies...Low infection rate in Arrow Lionheart* European trial
...opean trial. The CE-mark provides authorization to market the device within the European Economic Area for permanent implantation or "destination therapy". The Arrow LionHeart is the first left ventricular assist system to receive CE-marking authorization specifically for destination therapy. Study sites f...Pfizer's VFEND(R) receives FDA approval for treatment of esophageal candidiasis
....S. Food and Drug Administration (FDA) approval to market VFEND (voriconazole), a broad spectrum antifungal medicine, for the treatment of esophageal candidiasis. Candida organisms are normally found on skin and mucous membranes in healthy individuals, but in persons whose immune systems are weakened or ...GlaxoSmithKline Drug Discovery and Development Research Grant Program 2003
...leoside and nonnucleoside RT inhibitors now on the market work by inhibiting RT's polymerase activity, which is to copy the genetic materials needed to infiltrate the human cell. The DNA copy, however, remains associated with the original viral RNA, forming what's called an RNA/DNA complex. "To proceed ...PRAECIS PHARMACEUTICALS INC receives FDA approval for Plenaxis
...t at PRAECIS to bring an innovative product to the market and marks an important milestone in our transition...approval under the Mutual Recognition Procedure to market Plenaxis TM for the treatment of hormonally responsive prostate cancer patients. The Company is in...Computer-assisted breast imaging systems help find and characterize cancers
...ection but not classification -- have been on the market for a few years. But Sahiner and his colleagues hope their CAD research will advance the field by improving mammogram classification of lesions as malignant or benign, enhancing breast ultrasound imaging, aiding with detection and classification on f...Initial findings of first comprehensive study into ageing process published
...in health, wealth, social participation and labour market activity amongst the older population. Professor Marmot said: "This study is tackling one of the most important research questions currently facing society: how do we provide for an ageing population? By investigating the relationships between healt...Combination, order of anti-HIV drugs make a difference in first-time recipients
...ning how to use the many anti-HIV drugs now on the market to provide the maximum benefit for the longest period of time." Highly active antiretroviral therapy (HAART) employs combinations of anti-HIV drugs to help suppress the virus in people with HIV/AIDS. The goal of HAART is to combine three or more dru...Mayo Clinic develops new technology to improve diagnosis of arm and hand injuries and disease
...ds and fingers. Mayo has obtained FDA approval to market and commercialize these devices, making them available to other medical centers nationwide. Named Mayo Clinic BC-10 MRI Coils, these devices are highly sophisticated units used in taking detailed pictures of a particular part of the body. They produ...Urban areas organized in well developed partnering 'markets'
...onal and the other relational. The transactional market consists of encounters primarily for the purposes ...vely uncommitted relationships. The relational market functions in a more complicated way and is often guided by friends and family. People they know int...Study shows how well heartburn sufferers follow directions for over-the-counter Prilosec OTC
...s application process to the FDA for permission to market Prilosec OTC as an over-the-counter drug. More than 90 percent of consumers who decided to buy the drug had frequent heartburn, the condition for which Prilosec OTC has FDA approval. Only 3 percent took more than the recommended 14 daily doses, even ...Dietary supplements containing ephedra and caffeine may cause heart problems
... point out that the FDA has removed drugs from the market with lower QTc interval increases. In conclusion the authors write, "The ephedra- and caffeine-containing dietary supplement Metabolife 356 increased the mean maximal QTc interval and systolic blood pressure. Since the actual ingredient or ingredien...New dressing for wounds developed at Hebrew University
... different collagen-containing preparations on the market today made for treating wounds, for use in dentistry implants, and in cosmetics. All of them use collagen made from animal tissues, which requires specific adaptation in order to eliminate immunological rejection or to prevent microbiological infecti...Nonprofit pharmaceutical seeks drug approval next year
...neWorld Health's intention to bring paromomycin to market in India in the next year. Paromomycin is a treatment for visceral leishmaniasis (VL), also known as kala azar. An estimated 1.5 million people worldwide are infected with VL, and without treatment, the disease is fatal. "If a disease killed the e...NHS set for 'airline style' transformation
...ent's recent attempts to open up the UK healthcare market to new providers look set to continue, says the author. Will it work? Only time will tell. But if the airline business is anything to go by, things will certainly be different, and the cosy duopoly of the NHS and mainstream private providers will be ...A common cleanser is cheaper and faster way to separate DNA for genetic analysis
...savings of $37 million annually based on the total market for DNA gels in the United States. "In science, as in any other profession, to some extent, you accept what you're taught and everybody was taught to use the same tools for extracting the components of DNA," says Kern. "Scientists 30 years ago made ...Survey shows impact of psoriasis is more than skin deep
... Conducted in December 2003 by the NFO, a leading market research firm, the survey sampled 502 people with moderate-to-severe psoriasis to determine the effect the disease has on four crucial aspects of life: self-esteem, work/school, relationships (including sex life and intimacy) and social interactions....Study shows sponsors moving non-sedating antihistamines to a third tier realized greatest savings
...s and strengths of Claritin, which had the largest market share of the prescription NSAs, became available for sale OTC in December 2002. The study used data from 1,779 plan sponsors across Express Scripts' book of business in examining the financial impact on plans sponsors of their choice of prescriptio......watching with software that simulates demographic, market andreal-estate development? Alberti and her colleagues expect it toresult in a set of integrated models that detail how urbandevelopment and land-cover changes in the Puget Sound regionaffect diversity and nest predation for birds and householdprefer...