Tag: "marrow" at medical news
Cord blood stem cells save children with Hurler's syndrome
...he National Heart, Lung, and Blood Institute. Bone marrow
from adult donors can save some Hurler's patients,...ildren, said the researchers. Moreover, adult bone marrow
fails to engraft in 28 to 37 percent of Hurler's patients, meaning the donor bone marrow
does not ta...
NIH launches study of hematopoietic stem cell transplantation for severe, treatment-resistant lupus
...be harvested and cleaned. After the patient's bone marrow
is treated with immunosuppressant drugs to destroy...ne marrow. The stem cells will then repopulate the marrow
and body to establish a more properly functioning immune system. The initial treatment requires seve...
Researchers identify cancer-causing gene involved in aggressive leukemia, lymphoma
...ound that the HMG-I gene was overexpressed in bone marrow
samples from patients with leukemia. Resar says it is not yet known how overexpression of HMG-I interferes with normal cell growth and leads to the development of cancer in either mice or humans. She speculates that since the gene's proteins are inv...
Full recovery after cell transplantation for treating leukemia or lymphoma can take 3-5 years
...ematopoietic cell transplantation (receipt of bone marrow
transplant or stem cells transplant) is an effecti...llow-up for 319 adults who had myeloablative (bone marrow
suppression) HCT for treatment of leukemia or lymphoma. Of the 99 long-term survivors who had no rec...
New surgical device for long bone repair reduces X-ray exposure
...as the femur, a titanium nail is inserted into the marrow
cavity. To hold the bone in place, screws are drilled into small holes in the nail, which is the tricky part of the process. With the new tool, a Magnetic Targeting Device, a doctor may precisely locate the holes for the screws. The process calls for...
Cells from fat tissue turned into functional nerve cells
...ell as the experiments performed by others on bone marrow
stem cells, opens up new possibilities for the treatment of nervous system disorders or injuries. "We are trying to think about human disease in a new way," Gimble said. "Everyone is used to the concept of surgical, medical or pharmacological approac...
Study finds Velcade major improvement over standard therapy for relapsed multiple myeloma patients
...yeloma is a currently incurable cancer of the bone marrow
that causes a plunge in the production of vital red and white blood cells. Although relatively rare, it is the second most common type of blood cancer and accounts for 11,000 deaths annually in the United States. It is the fourth fastest-growing ca...
Researchers find strong familial tendency in rare form of lymphoma
...greater concentration of tumor cells in their bone marrow
than patients whose cancer cells lacked those antigens. "The high incidence of familial involvement in Waldenstrom's macroglobulinemia was a surprise even to us and has given us new insights that are helping our research efforts in finding the geneti...
Drug to fight virus in transplant patients moves forward in trials
...splant of hematopoietic stem cells, such as a bone marrow
transplant or solid organ transplantation, are at high risk of CMV infection, as are AIDS patients, fetuses and newborns. In these patients, CMV can lead to conditions such as pneumonitis or hepatitis, or to complications such as acute or chronic rej...
Donald W. Reynolds Foundation awards UT Southwestern $12 million to continue Dallas Heart Study
...covering whether stem cells from the heart or bone marrow
could repair an injured heart. That study is led by Dr. Daniel Garry, associate professor of internal medicine. The grant also will support an experiment that draws on neighborhood barbers to increase the detection and treatment of high blood press...
Cleveland stem cell investigators awarded $3.1 million
...sis that deterioration of blood stem cells in bone marrow
contributes to anemia and bone marrow
failure in the aging process. The ability to divide and faithfully produce more cells is an importan...
Jefferson scientists find new way to convert adult human stem cells to dopamine neurons
... Medical College have found a new way to coax bone marrow
stem cells into becoming dopamine-producing neuron...ratory, they were able to convert adult human bone marrow
stem cells into adult brain cells. Human adult bone marrow
stem cells also known as pluripotent ste...
New analysis links breastfeeding to reduced risk of childhood leukemia
...le AML accounted for 16 percent of cases. The bone marrow
of both ALL and AML patients produces too many immature cells that fail to develop into mature white blood cells. One of the 14 papers reviewed at UC Berkeley included a small case-control study authored by Kwan as part of the Northern California Ch...
Scientists identify key mechanism in estrogen's role in preventing bone loss
... in turn to enhanced T cell activation in the bone marrow
and extended T-cell lifespan. The investigators'...he effects of estrogen on immune cells and on bone marrow
in culture. They measured the level of TGFb in bone marrow
macrophages (BMM) and discovered that th...
Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
... from sibling donors may be more harmful than bone marrow
in pediatric leukemia patients. Researchers from ...plant-related causes than those who underwent bone marrow
transplants. It is estimated that nearly 30% of transplants from sibling donors in pediatric patien...
Churches nationwide issue plea for increased rates of African American organ donation
...ogram designed to demystify organ, tissue and bone marrow
donation, emphasizing the critical need in the African American community. This year's initiative is the largest ever, with participating churches urging congregations to strongly consider organ donation. "Seven years on dialysis took a serious t...
The effect of osteoporosis drugs on osteoarthritis of the knee
...subchondral bone thickening, osteophytes, and bone marrow
edema-like lesions than the women not taking thes...ing is particularly important because the MRI bone marrow
abnormality score appears to be a strong predictor of progression of structural deterioration in kne...
Mayo Clinic discovers one mechanism for why men and women differ in immune response
...eeded to reconstitute the immune system after bone marrow
transplantation. * protect cancer patients who are receiving immunotherapy treatments or who are vulnerable to infection as a result of chemotherapy. Significance of the Research Researchers and physicians have known for years that there is a diff...
Obesity linked to another cancer - leukemia in older women
... leukemia (AML), an often fatal cancer of the bone marrow
and blood. The results of the study are published ...ty with CLL. AML is cancer that starts in the bone marrow
in immature cells that normally should become white blood cells. Acute means the leukemia develops q...
Stem cell therapy effectively treats heart attacks in animals
... where they are plentiful. A special kind of bone marrow
stem cell, called a mesenchymal stem cell, was sep... developed stem cells were used. "While the bone marrow
adult stem cells do not have the same potential to develop into different organ tissues as do embryo...
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