Large portion of late-stage breast cancers associated with absence of screening
...two groups, which each contained 1,347 women, were matched for age and type of health plan. A key finding was that women who had not been screened one to three years prior to diagnosis were more than twice as likely to have late-stage breast cancer. This finding illustrates an important reason for rece...Novel drug-antidote strategy provides greater control of drug action
... a novel drug pair a potent anti-coagulant with a matched "antidote." Using this combination pharmaceutical...fects of existing drugs, researchers could develop matched drug-antidote pairs at the beginning of the drug development process to enable the control of drug a...Fox Chase Cancer Center researchers identify novel target for detecting ovarian cancer in blood
...e blood and peritoneal fluid DNA were obtained and matched from 50 patients with ovarian or primary peritonea... pattern of gene hypermethylation was found in the matched blood DNA from 41 of 50 patients (82 percent sensitivity), including 13 of 17 cases of stage I disea...Envisat Symposium report day 3: Satellites supporting Kyoto - our future is in our forests
...the Earth System. The multi-sensor Envisat is well matched for such an aim, the Symposium heard, and has demonstrated its ability to directly measure greenhouse gases. Teams from the University of Heidelberg, Bremen and the National Institute for Space Research (SRON) in the Netherlands showed how they are ...Cancer burden seen even many years after diagnosis
...rvivors and nearly 5,500 control subjects who were matched for age, sex, and level of education. Cancer survivors had a lower quality of life, more lost productivity, and more health limitations than the control subjects, and this high level of burden was seen even beyond 10 years after their diagnosis. Whi...Physical symptoms of depression may be misdiagnosed
...gardless of symptoms, were successful because they matched patient preference. Patients who had physical symptoms of depression were less likely to agree with a medical diagnosis of depression and thus tended to be nonaccepting of antidepressants, while 72% of patients with psychological symptoms who were p...Studies show ACTOS(R) (pioglitazone HCl) has positive effects on various components of dyslipidemia
...erapies to treat dyslipidemia. These patients were matched with controls that were not taking lipid-lowering drugs and all participants were given ACTOS (30 mg/day) for 16 weeks. Significant beneficial effects of ACTOS were seen on HDL ("good") cholesterol, fasting triglycerides, non-HDL cholesterol (total c...Diabetes increases deaths among people 65 and older
... 1994, and included 148,519 persons with diabetes, matched by age, gender and race with precisely the same number of people who did not have a diagnosis of diabetes in 1994. Deaths among both groups were recorded through Dec 31, 1999. During those 60 months, 59,369 (or 40 percent) of the people with diabete...Parents overestimate children's bike, car safety habits
...f they are used. In the current study, the largest matched analysis on injury prevention, researchers surveye...ental behavior and the child's behavior. Among the matched parent-child responses, 15 percent of the children said they never use a bicycle helmet and 88 perc...Matching method helps doctors successfully transplant higher-risk kidneys
... a potential recipient. "In the past, kidneys were matched exclusively by blood and tissue type," said Stratta. "Now, we are matching based on age, weight and kidney function. Someone who weighs less doesn't need as much transplanted kidney capacity; it is a concept that is in evolution." Stratta and colleag...Cord blood stem cells save children with Hurler's syndrome
...with severe Hurler's syndrome who lack a perfectly matched and related adult bone marrow donor." Patients with a milder form of the disease, with no brain involvement, can receive enzyme therapy alone. However, because enzymes do not cross the blood-brain barrier, they cannot repair the brain damage that occ...Preimplant test offers option of having child to serve as stem cell donor to sibling in need
... genes, and embryos were transferred that were HLA matched to affected siblings. The researchers found that a... with selective abortion of fetuses who are poorly matched with the living affected child. This approach, while apparently rare, has been reported." "What are ...Some infants recognize, respond to social eating cues
...thers said they were overeaters. These groups were matched to 16 babies who were not problem eaters. All the babies were growing normally and had no underlying medical problems. Watching the videotaped feeding, the researchers marked every time the mothers handled the food or fed the babies a bite and...Lower temperatures improve outcomes after bypass surgery
...f balance -- the higher demands for oxygen are not matched by increased blood flow. Irrespective of its oxygen supply and demand, hyperthermia can also directly injure brain tissue by itself, Grocott said. It is during this period of time of inadequate oxygen supply that may help explain why up to one-third ...Imaging test could be used to diagnose schizophrenia
...isted of 17 outpatients with chronic schizophrenia matched with 17 healthy persons in Vancouver, B.C. Another group consisted of eight patients and eight healthy persons in Hartford, Conn. "These results have the potential to provide a powerful, quantitative clinical tool for the assessment of schizo...Newborn testing for immune disorders could save lives
...from donor bone marrow, typically from a parent or matched sibling. Transplant recipients do not need pretran...of age. All 15 recipients of marrow from perfectly matched donors and 89 of the 121 recipients of T cell-depleted marrow from related donors are among the surv...Improving the chances of successful organ transplants
...g a more accurate organ match. "Usually organs are matched to recipients by comparing tissue types and selecting those pairings with the smallest genetic mismatch. Using this method alone, however, ignores sensitisation which can turn a slight mismatch into an unacceptably high risk," explains Dr Nikolai Sch...Online tool estimates long-term chance of surviving prostate cancer
... and co-morbidity (those with additional diseases) matched controls. Based on demographic and clinical variab...omized study design. And the inclusion of a large, matched control group is a great strength of our study." While the study, which was awarded a first prize by...Hopkins' young researchers honored for their contributions
...biomedical science when they died. But the awards, matched to recipients by a faculty committee headed by Se-Jin Lee, M.D., Ph.D., aren't just about honoring people close to Hopkins. Recipients say they get a confidence boost from the recognition, and the entire celebration helps encourage all students and p...Embryonic stem cells induced to develop into bone marrow and blood cells
... eventually eliminate the need to find genetically matched human bone marrow donors for persons with leukemia...le to patients due to inability to find a suitably matched donor. Human embryonic stem cell lines can be cultured indefinitely, providing a permanently renew...