Late developers may run higher risk of infection than sexually mature younger teens
..., whose breasts were more developed, more sexually mature (older gynaecological age), and who had infrequent menstrual cycles (oligomenorrhoea) were significantly less likely to have any of the infections. After taking account of age, number of sexual partners, and behavioural risk factors, young gynaecol...'Smart' immune cells kill more cancer
...lling mode. The marrow T-cells identified not only mature myeloma cells but the primitive cells responsible for the disease. Activated bone marrow T-cells stopped the growth of 86 percent of myeloma stem cell colonies compared to 47 percent for activated t-cells taken from circulating blood. The researche...Dual testing better for monitoring new cases of HIV
...m a new infection produces weak binding, whereas a mature infection involves strong binding. In a cross-sectional study of more than 1,500 patients showing up in the Hopkins Emergency Department from June to August 2001, the testing of blood samples by STARHS showed 11 cases of new infection, but dual test...Newly identified gene cluster on mouse X chromosome provides insights into fertility
...ffects the neighboring germ cells, pushing them to mature and become sperm." "Another thing that some Rhox genes could be doing is regulating the production of proteins within Sertoli cells that allow the neighboring germ cells to survive," Wilkinson says. "If you knock out Rhox5, many more germ cells die t...JCI table of contents, January 20 2005
...as increased and the CD4+ T cells were prompted to mature into what are known as effector cells, capable of exerting an immune function that helps coordinate other cells of the immune system to eliminate the virus. The study will appear online on January 20 in advance of print publication in the Februar...T cells target HIV in a relationship on the rebound
...as increased and the CD4+ T cells were prompted to mature into what are known as effector cells, capable of exerting an immune function that helps coordinate other cells of the immune system to eliminate the virus. The study will appear online on January 20 in advance of print publication in the February 1 ...Researchers describe how human blood stem cells transform themselves to repair injured animal hearts
...rm new blood vessel cells, they "differentiate" or mature by themselves, presumably to patch damaged mouse blood vessels with human cells. These findings should help resolve debate within the field as to whether stem cell transfer actually creates new types of cells that last within a heart, says the study...Stanford study finds new method improves chemotherapy survival in mice
...enitor cells seems to be more effective than using mature neutrophils, the researchers said. The resea...loid progenitor cells may be preferential to using mature neutrophils for at least two reasons. First, the myeloid progenitors give rise to a broader spectrum...Lab study: Protein delivered via genetically engineered virus slowed glioblasoma multiforme growth
...tein, hsFlt3L to stimulate the production of fully mature immune cells within the brain," said Maria Castro, Ph.D., co-director of the Gene Therapeutics Research Institute at Cedars-Sinai Medical Center and the senior author of the study. "Since gene therapy has given us the tool to deliver this protein, o...Stem cells of limited use for cardiac muscle repair
...te into these regions and proliferate, they do not mature into new cardiac muscle cells. A series of previou...uscle, but we found that they never become normal, mature muscle cells." The researchers used bone marrow side population cells (BM-SP), a sub-set of the s...Stem cells' repair skills might be link to cancer
... normal, primitive stem cells or from the tissue's mature cells. "Cancers associated with chronic irritation may be a good setting in which to determine whether stem cells are the starting place of tumors," says Phil Beachy, Ph.D., professor of molecular biology and genetics in Hopkins' Institute for Bas...Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
...lls - immature cells found in the bone marrow that mature into red blood cells, white blood cells, and platelets. Doctors have traditionally treated children with leukemia using bone marrow donated from a sibling when available, or from an unrelated volunteer donor. Another approach is peripheral blood st...New analysis links breastfeeding to reduced risk of childhood leukemia
... too many immature cells that fail to develop into mature white blood cells. One of the 14 papers reviewed at UC Berkeley included a small case-control study authored by Kwan as part of the Northern California Childhood Leukemia Study. That study was funded by the National Institute of Environmental Health...Promise of stem cells amplified
...ral groups of researchers have watched these cells mature into what look like neurons. But the true test of a neuron's function--electrical conductivity--had not yet been seen. Iver Langmoen, MD, and his colleagues harvested the adult neural stem cells from the ventricular zone of patients undergoing brain...Lab study defines and blocks mechanism that lets brain tumors sidetrack immune response
...s exposed to gliomas that overexpress COX-2 become mature dendritic cells that produce significant levels of IL-10 and decreased levels of IL-12. This leads to suppression of cellular immune responses at the site of the tumor and systemically." The study was conducted using two established glioma cell lines...Antioxidant component of green tea blocks new but not established arterial plaque in mice
... evolving carotid plaques but had no effect on the mature plaques in the aorta reinforce the theory that intervention is effective in early but not late stages of atherosclerotic development. It appears that antioxidant therapy would have therapeutic benefits only if initiated during a critical window very ...Cord blood stem cells save children with Hurler's syndrome
... these children. Stem cells in cord blood are less mature than adult bone marrow cells and thus do not need to perfectly match the patient's immune-related blood proteins called antigens, said Kurtzberg. Moreover, cord blood stem cells appear to repair more of the damage caused by Hurler's syndrome than doe...Researchers define mechanism that enables stem cells to track migrating brain tumor cells
... advanced stage of differentiation but are not yet mature astrocytes, a subcategory of glial cells. Astrocytes are comparatively large, star-shaped cells that influence the activity of neurons and provide structure for the cells of the brain. The researchers also found that these astrocytic precursors expr...Sounds of New York, evidence for a preferred ear, ultrasound for the eye
... fired. The lone whales making this sound were all mature males, so the researchers have concluded that the gunshot signal serves as either an antagonistic sound directed toward other males, an advertisement signal to attract females, or a combination of the two (4aAB12). Other talks will focus on birds' s...When 'switched on' muscle stem cells morph to resemble nerve cells
...eral years ago when studying how neural stem cells mature into neurons. Neuronal stem cells go through a series of steps before they differentiate into neurons, and each step is initiated by expression of different sets of genes. The last step, in which a large number of genes are activated, is only made po...