Tag: "mechanism" at medical news
AIDS Treatments Seek To Eradicate Virus, Restore Immunity
...V by crippling an enzyme crucial to its survival,a mechanism
different from other anti-viral compounds. The three drugs are expected to reduce the "viral load" or theamount of HIV in patients' bodies, by 99 percent, said Dr. John Bartlett,who heads Duke's Infectious Diseases Clinic. "But what we need to dois...
Scientists Produce New Anti-Malarial Compound
...ake the new compounds. Thecentral component of the mechanism
is a ring of atoms, present inatemisinin and the n...o the malaria parasite. "Our understanding of that mechanism
has allowed us to designstructurally simpler compounds that would follow that chemicalmechanism," Po...
ACTG 315 Preliminary Results: Drug Cocktail Restores Partial Immune Function
... respond. Data are being analyzed to ascertain the mechanism
underlyingrestoration of circulating T cells in patients receiving HAART. "ACTG 315 is the first of aseries of studies developed by the new ACTG Immunology/Immune-BasedTherapies Research Agenda Committee," comments Dr. Fox, "thattakes full advantage...
Kids Near Airports Don't Read As Well
...language acquisition is an underlying, intervening mechanism
that accounts for some of the noise-reading deficit link." Evans and Maxwell also suspect that other factors may be at work in noisy schools and neighborhoods, such as teacher and parent irritability and their reluctance to talk as much, use as many...
Study Injects New Interest In How Vaccines Work
...surface." The study raises new questions about the mechanism
by which aluminum hydroxide works, Hem says. The f... Hem says. Though scientists have puzzled over the mechanism
by which aluminum hydroxide increases the production of antibodies, the tiny amounts of the substanc...
Mother's Milk: Nutrition And Nurture For Infants -- And The Best Defense Against Disease
...nced over those of formula-fed babies.One proposed mechanism
to explain this observation is that certain antibodies inbreast milk may mimic bacterial and viral proteins. Such mimicry would have theeffect of priming the infant immune system to respond more vigorously when laterexposed to actual pathogen protein...
New Approach To Multidrug Resistance
...porarily inhibits production of a prime protective mechanism
usedby tumors -- a molecular pump called P-glycoprotein that flushes drugs out ofcells. The study, conducted by Associate Professor of Pharmacology andToxicology Joshua Hamilton at Dartmouth Medical School, with colleagues from themedical school and ...
Some Good News In Treating Infection Common To HIV Patients
...use of another illness. Attempts to determine the mechanism
of desensitization were unsuccessful. Despite this, Kazanjian says the importance lies in the successful long-term desensitization of a vast majority of the patients previously allergic to Bactrim. "It's quite important," he says, "because we can now...
Snipping Inflammation In The Bud; New Agents May Provide Relief
... is lost from the cell surface, the cell's docking mechanism
isno longer available, and the sheared L-selectin proteins are turned loose in thebloodstream. There, the shed protein can attach themselves to theL-selectin-binding proteins on other cells, thereby acting as inhibitors todeter the inflammation respo...
Combined Therapy Improved Care Of Patients With Type 2 Diabetes Proper Use Of
New Oral Medications Evaluated
... "Therefore, it isessential that we understand the mechanism
by which these novel oral medicationslower patients' blood glucose. We then will be able to combine them in arational fashion for effective treatment." According to Silvio E. Inzucchi, M.D., assistant professor of medicine(endocrinology), results o...
BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference
...both of these agents was supported by BioNumerik's mechanism
basedcomputational studies and supercomputer simulations." Frederick H. Hausheer, M.D., BioNumerik's Chairman and Chief Executive Officer,presented these findings at the 89th Annual Meeting of the American Associationfor Cancer Research held March 2...
PITT Researchers Demonstrate Human Brain's Natural Mechanism For Guarding Against Errors
...r. "Until now, we didn't know what type of mechanism
the brain employed tomonitor its own performance and regulate behavior," continued Dr. Carter. "Nowthat we've found one such mechanism, we can further explore it with the hope ofunderstanding its role in disorders like schizophrenia and depression."...
Neurotransmitter-Induced Electrical Activity Identified As Key Regulator Of Synaptogenesis
...tional glycine receptor polypeptides. This passive mechanism
concentrates the receptors at the developing postsynaptic site. In the forties, Donald Hebb postulated that the coincident activity of both pre- and postsynaptic nerve cells constitutes the electrophysiologica...
For Patients With Advanced Prostate Cancer, Newly Evaluated Drug May Offer Pain Relief And Mild Delay In Disease Progression
... orliver toxicities were rare in both groups. The mechanism
of suramin's action is complex, said Small, and still has not beenfully delineated. Prostate cancer, the most common cancer in men, accounted for more than 40,000deaths in the United States in 1997. Approximately 300,000 American men arediagnosed w...
Old Drugs, New Tricks
...rves as a marker of vascularcell inflammation. The mechanism
of action of these PPARa receptors in the vascular wall was alsoelucidated. The receptors exert at least part of their anti-inflammatory effectby interfering with a signaling pathway called NFkB, which is also activatedduring inflammatory cytokine pr...
Research Explains Lithium's Dual Anti-Manic/Anti-Depressive Effect
...g it back into thecell for reuse. If the reuptake mechanism
malfunctions, inappropriate concentrations ofneuro...re especially interested to find that the reuptake mechanism
in the 18lithium-treated mice was stabilized in a very narrow range, compared to the 18controls," he...
By Losing (Molecular) Weight, A Clot-Dissolving Drug May Be In Better Shape To
Help People Avoid A Repeat Heart Attack
.... Heparin seeks out the protein and turns off the mechanism
whichmakes the protein come together. Heparin helps keep blood flowing normallythrough the vessels by preventing proteins such as von Willebrand factor fromclogging the vessels. Enoxaparin was found to be the better "binder," and its superior suppre...
Drug Reduces Heart Attack, Death Rates In Patients With Unstable Angina
...t-formingprocess. Eptifibatide's different mechanism
of action means patients alreadytaking aspirin or heparin may be able to add Eptifibade to their regimen of drugtherapies, doctors said. The study results showed that Eptifibatide reduced heart attack anddeath by an overall 1.5 percent world...
Credit Cards Could Double As Donor Cards
...t needs to be devised and that the phraseology and mechanism
for non-consents needs to be developed. He concludes that credit cards could radically improve the supply of donor organs for transplantation. Contact: Dr Neil Davidson, Consultant Physician, Department of Medicine, Armed Forces Hospital, PO Box 519...
BioNumerik Reports The Supercomputer Supported Discovery Of New, Non-Toxic Chemotherapy Protecting Agent
...nars in Oncology which describes the discovery and mechanism
of action of anew non-toxic, second-generation platinum protecting agent, known as BNP7787,which appears to substantially reduce the toxicity of platinum-type anticancerdrugs, such as cisplatin and carboplatin. Cisplatin and carboplatin are widely u...
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