Vanderbilt Cancer Center Discovery May Help Overcome Resistance To Anti-Breast Cancer Drug
... the drug. "This suggested to us that TGF-beta was mediating the resistance tothe anti-estrogen," Arteaga said. When the cell lines were studied in culture rather than in the animal, however,adding TGF-beta antibodies did not restore tamoxifen sensitivity. This stronglysuggested that something in the mouse -- ...People With Brain Injury To Frontal Lobe Don't Get Punch Lines -- Prefer Slapstick Humor!
...s a"silent brain region" that was not important in mediating higher cognitivefunctions. "Through studies such as this one, we have evidence that the frontal regionplays a critical role in higher cognitive functions such as humor, emotions andpersonality," says Dr. Stuss. "It receives information from almost a...Hormone involved in reproduction may have role in the maintenance of relationships
...e study. "Our study indicates that oxytocin maybe mediating emotional experiences in close relationships." The study builds upon previous knowledge of the important role oxytocin plays inthe reproductive life of mammals. The hormone facilitates nest building and pupretrieval in rats, acceptance of offspring ...We do 'feel with the mind's eye,' confirm Emory researchers in Nature
...(the occipital cortex), and then, the brain region mediating the sense of touch(the somatosensory cortex). When a key region of visual cortex (the parieto-occipital cortex) wasblocked, subjects were significantly less successful in discriminating theorientation of the grating via touch, according to f...... growth. "The current identification of a receptor mediating Nogo-66 action should greatly facilitate the development of agents with pharmaceutical potential in a diverse group of neurological conditions, such as spinal cord injury, brain trauma, stroke affecting white matter, and chronic, progressive multiple......ion of programmed cell death, called apoptosis, in mediating the progressive cascade of cell death observed after TBI. Dr. McIntosh and his colleagues have also pioneered research into the mechanistic relationship between head injury and Alzheimers Disease and other neurodegenerative disorders and were the fir...Free radicals mediate arsenic's harmful effects
...species, in particular the role of mitochondria in mediating the genotoxic effects of arsenic....Eating breakfast may keep colds & flu at bay
...n brain chemistry which take place and the role of mediating factors is now needed. Medication also needs to be developed which not only reduces symptoms but improves the performance and mood of people who have minor illnesses such as the common cold' he adds....Rush studying the role of intra abdominal fat in coronary artery disease risk in women
... WISH study is also the first study to examine the mediating role stress plays in heart disease risk among post menopausal women. Participants will be given a saliva test to determine the amount of cortisol that is present in the morning and at night -- times when levels are typically at their highest. Cortis...Estrogenlike drugs may eventually help postmenopausal women with weight gain
...Ms to determine the roles of the Eα and ER in mediating food intake and body weight gain in OVX rats. In addition to contributing to the understanding of the mechanisms by which estrogens modulate food intake and body weight, these studies help determine the feasibility of using SERMs in the future to pr......essive calcium channel openings, but the molecules mediating the phenomenon are still unclear. This week, two papers examine the roles of presynaptic calcium channels in facilitation. Voltage-dependent relief of G-protein-mediated channel inhibition of Cav2.2 channels was responsible for this form of short-ter...