DNA Imaging to Design Better Drugs
... serves as co-advisor to the project. "Now when a medicinal chemist synthesizes a potential drug, we canvery quickly tell them if it binds to DNA, how tightly it binds, and themode by which it binds," he added. One of the major advantages of the new assay is it shows researchershow drugs affect single DNA mo...Chemist Turns To Self-Assembly To Create New Drugs
...y and an expert in the synthesis of biochemicaland medicinal compounds. "The Miller group has clearly shown thatthis approach makes sense and that it can work. Nature is a hugebiodiversity generator, and they've found a way to mimic thisprocess in the laboratory." Miller's technique relies on atoms of tra......stem, along with its high throughput screening and medicinal chemistry capabilities, to identify the two series of drug leads reported ontoday. Signal has expanded its SERM gene regulation program to target and treat otherestrogen-mediated diseases, particularly cancer. The Company recently completeda serie...UT Southwestern Study To Test Efficacy Of St. John's Wort For Treatment Of Depression
...about natural substancesthat people are taking for medicinal purposes. The National Institute of Mental Health agreed to fund the project withoutfinancial input from pharmaceutical companies....UK researcher develops nicotinic drugs with R.J. Reynolds
...nddepression. Crooks has been studying the medicinal chemistry of nicotine andnicotine analogs since the early 1980s. During this time, he and his coworkershave completed extensive studies on the metabolism and pharmacokinetics ofnicotine in and around the brain. Collaborating with colleague...1999 AAPS Annual Meeting abstracts debut online
...nces; economic, marketing,and management sciences; medicinal and natural products chemistry; pharmaceuticsand drug delivery; pharmaceutical technologies; pharmacokinetics,pharmacodynamics and drug metabolism; and regulatory affairs. Scientists fromevery corner of the globe--including Australia, Brazil, China...Studies suggest that eating chocolate may be good for your heart
...esentations about the history of chocolate and its medicinal uses and in vitro studies on the interesting antioxidant compounds in chocolate....Expert calls for common sense, science in national response to medicinal herbs
... common sense with good science in its response to medicinal herbs. That's the view of Dr. Varro E. Tyler, one...t the first international scientific conference on medicinal herbs. "The ancient origins of herbal medicine are indisputable," he said. Archaeologists have fou...Conference to examine nutritional supplements, medicinal herbs for managing health problems
...ific studies about the safety and effectiveness of medicinal herbs, Gaylord said. On Friday (March 24) at 9 a.m., Dr. James A. Duke, an ecologist, will speak on "Botanical Medicine: The Amazon Experience." Herbalist Steven Foster of the Steven Foster Group in Fayetteville, Ark., will discuss "The Herbal Indus...St. Paul researcher receives national award
...ective or more selective," explained Portoghese, a medicinal chemist at the University of Minnesota. "And we can gain insight into how molecules bind by modifying them and their receptors in a systematic way." For example, his team has developed genetic tools used to replace a bulky receptor building block wit...Gas prices too high? Scientists converge in Idaho to discuss future energy resources
...y: The following papers will discuss the potential medicinal properties of exotic plants. "Isolation and charac...terization of medicinally active compound from the medicinal plant pyllanthus fraternus," E. Nartey, Brigham Young University, Friday, June 16, 2:10 p.m.; and "S...First protein 'biochips' may deliver improved detection, diagnosis
...tory tens of thousands of these have been used for medicinal purposes," Ladisch says. "Up to now, we've been uncovering the actual proteins or molecules at the rate of just a few a year. This research has the potential to increase that number several fold. "What we would have would be a high-tech litmus paper........ Hirschmanns seminal contributions to organic and medicinal chemistry also include the first chemical synthesis in solution of an enzyme, ribonuclease, in 1969, regarded as one of synthetic organic chemistrys noteworthy achievements of the 20th Century. Early in his career, in 1952, he discovered that chemic...European commission grants "orphan" status for new acute myeloid leukaemia treatment
...nated Mylotarg(gemtuzumab ozogamicin)as an "orphan medicinal product." The Commission decision follows a posit...omising oncology pipeline." As a designated orphan medicinal product, Mylotarg will have access to the Commission's "centralised" procedure for assessment of the...First medicinal cannabis studies approved by research center
...study on the effects of repeated administration of medicinal cannabis on driving ability (acute and/or long-term). Patients with HIV-related neuropathy or spasticity associated with M.S. will be evaluated for impairments using driving simulator assessments. The Research Advisory Panel of the State of Californ...Wilmington chemist wins national award for drug development
...market in 1996 and 1998, respectively. Himself a medicinal chemist, Anderson said the project groups he direc...ire in 1963. He is a member of the ACS division of medicinal chemistry....Duke chemists synthesize fungus compound that could lead to oral diabetes drugs
...se molecules we've been working on might have what medicinal chemists sometimes call a privileged structure.' "There are certain kinds of structures that keep showing up over and over again in biologically active molecules, steroids being an obvious example. What we're hoping is that this initial hit has g...UIC Nature paper points to new drug discovery direction
...ics work. Alexander Mankin, associate professor of medicinal chemistry in the UIC College of Pharmacy, and his team have found that ribosome can remain functional even after alterations are made to the one nucleotide understood by researchers to be critical for catalytic activity. "The expectation was that if ...Patients may overestimate risk of side-effects from qualitative drug information
...al risk. To make informed decisions about taking medicinal drugs, people need accurate information about side...annot be expected to make informed decisions about medicinal drug taking. Our results strongly suggest that the qualitative descriptions recommended by the EU le...UNC studies add new dimension to 'lock-and-key' theory of drug action
...Mailman, professor of psychiatry, pharmacology and medicinal chemistry, Dr. Gerry Oxford, professor of cell and... Dr. David Nichols, professor in the department of medicinal chemistryand molecular pharmacology at Purdue University, Dr. Richard Todd, Blanche Ittleson profess...