Tag: "membrane" at medical news

Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients

...ioreactor a tube-shaped device containing a fiber membrane and 7 billion liver cells from pigs. These cells are isolated, cryopreserved (frozen) and thawed according to techniques originally developed by the Cedars-Sinai researchers. "The blood is removed at a fixed rate, detoxified and treated in the variou...

Unraveling the secrets of the brain's smallest cells

...y applying the patch-clamp technique, where a cell membrane is gently sucked onto a glass pipette which records small electrical signals coming from the cell, UCL researchers were able to see the granule cell layer at work, confirming predictions made over 30 years ago by the celebrated English theoretical ne...

Discovery sheds light on how cancer cells grow and divide

...ves to integrate signals from the cell surface and membrane trafficking with cell division." Significance of the Mayo Clinic Discovery The newly described relationship between Dynamin-2 and the centrosome poses the intriguing possibility that their partnership connects the cell's surface and its interior vi...

Latest fashion fad concerns eye M.D.s

...to half moons, are implanted into the eye's mucous membrane or the conjunctiva. "My concern would be that it might cause foreign body granuloma or scar tissue," said Academy spokesperson, Wayne Bizer, D.O., a comprehensive ophthalmologist from Ft. Lauderdale, Fla. "The implant could also allow bacteria to ge...

Existing therapies applied to new use in broader spectrum of cancer care

... through cell surface receptors, and GABA receptor membrane proteins are present not only in the brain, but on colon and ovarian cancer cells as well. Premal Thaker, M.D., and colleagues, tested whether Nembutal activated GABA receptors on the cancer cells both in culture and in vi...

Researchers say criterion for diagnosing child abuse based on faulty evidence

...h is a buckling of the retina, the light-sensitive membrane that lines the back of the eye. The injury has been reported in shaken baby syndrome, caused by vigorous shaking of an infant or young child. The shaking may cause bleeding around the brain and in the eyes, resulting in blindness, and can also resul...

Effectiveness of safer smallpox vaccine demonstrated against monkeypox

...llular enveloped virions, IMVs with an added outer membrane that play a large role in spreading the disease within the individual. To be effective, a vaccine needs to protect against both forms of the virus, and each form requires a different set of antibodies to destroy it. In addition to measuring antibodie...

Tiny molecular motors shed light on cell function, say Stanford researchers

...inds to the webbing between the fingers - the cell membrane between the stereocilia - and then as the legs wal...ia rigid. As the motor continues walking, the taut membrane strains the motor and distorts its shape, which turns the motor into an anchor. If the webbing/membr...

Studies focus on vascular spasm as a common cause of cardiomyopathy

...cused on mice with genetic defects that weaken the membrane of heart muscle cells. By the age of six months, ...ckets of mild, early cellular damage caused by the membrane defect actually caused nearby blood vessels to spasm, which led to localized damage and even death o...

Can nanopulses heal?

...ef to generate an electric charge across the outer membrane of cells, but they do affect structures within cells. One of the main effects seems to be calcium release from a cellular structure called the endoplasmic reticulum. "In a nanosecond, we cause this major physiological event in the cell," says Vernie...

Ultrasound-guided liposomes boost imaging, target drug/gene therapy

...ergy of the microbubble, which then opens the cell membrane and allows drugs to enter. McPherson, who is Lester B. and Frances T. Knight Professor of Cardiology and professor of medicine at the Feinberg School of Medicine at Northwestern University, believes that the ultrasound technique may further unders...

7-month-old is youngest recipient of artificial corneal transplant

...lanted, and a transparent sheet made from amniotic membrane was used to protect Lukas' eye and allow light in. ...

Mechanical support could increase survival of children requiring heart transplantation

... artificial heart and lung device (extra-corporeal membrane oxygenation (ECMO). Children were prioritised on t... listing and a short waiting time, extra-corporeal membrane oxygenation seems to provide the safest form of support." In an accompanying Commentary (p 1948), Ma...

New study in Pediatrics shows nitric oxide therapy for newborns effective and cost saving

...nvasive surgical procedure known as extracorporeal membrane oxygenation (ECMO), which involves cutting a newborn's jugular vein and putting the baby on a heart-lung machine to oxygenate the blood. Besides being invasive, the procedure has the potential to cause severe complications. Nitric oxide, by contrast...

New study in Pediatrics shows nitric oxide therapy for newborns effective and cost saving

...nvasive surgical procedure known as extracorporeal membrane oxygenation (ECMO), which involves cutting a newborn's jugular vein and putting the baby on a heart-lung machine to oxygenate the blood. Besides being invasive, the procedure has the potential to cause severe complications. Nitric oxide, by contrast...

JCI Table of Contents

...hat fibronectin attachment prevents activation and membrane association of Rac2 via integrin signaling. The integrins cause suppression of the activation of Rac GTPase by the membrane-localized regulatory exchange factor, Vav1. The authors propose that they have defined a novel inhibitory pathway initiated by...

Glycerin may help skin disease, study finds

...ts fats or lipids in the external, protective cell membrane to cell signals. Phospholipids are fats found throughout the body that make up much of the plasma membrane lipid bilayer that encases each cell and helps keep it from mixing with other cells. All cells have ...

GlaxoSmithKline Drug Discovery and Development Research Grant Program 2003

... and also of a co-receptor protein embedded in the membrane of the cell," Dr. Farzan said. Proteins which act as co-receptors for HIV are CCR5 are CXCR4. The first step in HIV entry takes place when glycoprotein "spikes," which include a protein called gp120 bind with the host cell receptor CD4. This trig...

New evidence links inflammation to venous disease

... contained microparticles small fragments of cell membrane from degraded cells. Most of these microparticles came from immune system cells called leukocytes, but some were derived from blood platelets, which are responsible for clot initiation. Additionally, some may have come from endothelial cells lining v...

Novel delivery system devised for toxoplasmosis treatment

...toxic method of transporting drugs across multiple membrane barriers and even into cysts of Toxoplasma gondii, the single-celled microorganism that causes toxoplasmosis. It also describes a new therapeutic target within this common parasite. "This is a major step forward in developing ways to treat one of ma...

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