New study supports use of PET scans in early diagnosis of Alzheimer's disease
...right neocortical areas. Such a pattern of coupled metabolic reductions between the deep and surface brain may make PET even more accurate at differentiating AD from other forms of dementia," said lead author Lisa Mosconi, MD, of the Department of Clinical Pathophysiology Nuclear Medicine Unit of the Universit...Detection at a distance for more sensitive MRI
...n can be dissolved in chemical solutions or in the metabolic pathways of biological systems, then concentrated for more sensitive detection. Since xenon is not normally present in biological or geological samples, its signal stands out clearly against a noiseless background. Other signal carriers can also be u...Genome sequence reveals leaner, meaner intestinal parasite
...last, a cellular component that provides essential metabolic functions in related parasites, including those th...d parasites, and, as a result, can carry out fewer metabolic functions on its own. Because Cryptosporidium has been so difficult to study up until now--presumab...Nanotech imaging, molecular fingerprints and signatures hold promise for cancer
... "Cancerous prostate cells produce molecular metabolic 'fingerprints' that differ from the metabolic 'fingerprints' of healthy prostate cells," said Leo L. Cheng, Ph.D., Massachusetts General Hospital,...Mayo Clinic researchers discover gene mutations that 'ignore' stress, lead to heart failure
...stress. When this happens, they fail to decode the metabolic signals that synchronize the flow of potassium and calcium. Implications of Research In principle, researchers can apply these findings to other patients with heart failure and look for other stress-reactive proteins that miscommunicate vital elec...Exercise improves cancer survival, reduces cancer risk, scientists say
...udy, leisure-time physical activity is measured in metabolic equivalent task hours per week (met-hours/week one met is the energy expenditure and caloric requirement at rest. One hour of walking represents three met-hours of physical activity.) The researchers looked specifically at exercise beginning two y...Fatty acid pathway, glucose combine to produce triacetic acid lactone
...active and energetic compounds. FAS-B is a primary metabolic enzyme with multiple functions, and it may be used to make many diverse value-added compounds, said Zha's adviser Huimin Zhao, a professor of chemical and biomolecular engineering and of chemistry at Illinois. To accomplish their task, the researcher...Lung cancer now leading cause of cancer death in women
...ger cancer growth and hormonal changes. "Genetic, metabolic and hormonal factors all are important to the way women react to carcinogens and lung cancer. This information should impact how we evaluate and screen patients who smoke and how we direct smoking cessation and lung cancer prevention programs," Patel...Lung cancer in women is a 21st century epidemic
... be due, in part, to estrogen signaling. Genetic, metabolic and hormonal factors also play a role in the way women react to carcinogens and lung cancer. However, women's longer survival periods once they have lung cancer cannot be accounted for solely by a longer life expectancy or an imbalance of other prog...Alarming rise in incidence of lung cancer and death in women
...but a recent review article suggests that genetic, metabolic and/or hormonal factors may also be responsible for the increase in lung cancer in women which has reached epidemic proportions in this country. The review article examining women and lung cancer by Jyoti D. Patel, M.D., of the division of Hematolog...Lung tumor therapies improved by combining CT and PET scans
...hem to highlight such differences as the increased metabolic activity of a tumor. For the study, researchers compared therapy plans designed by different physicians for 26 lung cancer patients. Two therapy plans were devised for each patient: A physician with access only to CT scanning results created one ...Low-dose transdermal estrogen viable short-term treatment for menopausal women
...es. Both lipids play a role in the development of metabolic syndrome, which becomes more common in women as th...predictor of type 2 diabetes. "When women with the metabolic syndrome require HT for the relief of their vasomotor symptoms, transdermal E2 can provide the addit...1st data show CRESTOR highly effective at lowering LDL-C in patients with type 2 diabetes
...NTATM, and a novel treatment for type 2 diabetes / metabolic syndrome, GALIDATM....Estrogenlike drugs may eventually help postmenopausal women with weight gain
...in thyroid function, with a subsequently decreased metabolic rate. With lowered metabolism, fewer calories are required to maintain current weight, and if caloric intake remains the same, then weight will increase. Another theory is that the weight gain is due to age-related decreases in muscle mass. Because m...Rare Chinese mushroom derivative can improve capacity, endurance, in sedentary elderly
...acity, endurance performance, and exercise related metabolic alterations before, in the middle of, and after the 12-week study treatment with CordyMax (3 g/day). Results The researchers found: (1) Maximal exercise Peak volume of oxygen (VO2peak) consumption was increased by 5.5% in CordyMax group (p=0.00...Newborn testing for immune disorders could save lives
...mple now taken from newborns to screen for certain metabolic disorders. Nine forms of SCID have been identified in the past 10 years, caused by mutations of single genes. However, Buckley has treated 30 patients without mutations in the known SCID genes, making it likely other causes are yet to be discovered. ...Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
...c poisoning, medication interactions or overdoses, metabolic disorders, and some types of viral hepatitis. Achilles A. Demetriou, MD, PhD, Chairman of Surgery at Cedars-Sinai and the study's principal investigator, has been pursuing treatments for acute liver diseases since 1976 when he began studying liver ce...Research news from Tufts University, Friedman School of Nutrition Science and Policy: May 2004
...of the US population have a condition known as the metabolic syndrome, predisposing them to increased risk of t...lycemic index was associated with a higher risk of metabolic syndrome in the same population. The glycemic index characterizes the rate of carbohydrate absor...Lower temperatures improve outcomes after bypass surgery
...cools the circulating blood in order to reduce the metabolic needs of the brain and other vital organs. In earlier studies of the effect of slower rewarming, Duke researchers found that patients who were allowed an additional 10 to 12 minutes to return to normal body temperature scored almost one-third better ...Testosterone replacement improves muscle strength, function in HIV-infected women
...ations in their hair, skin or voice or any related metabolic changes. "Although natural testosterone delivery products like the patches used in this study are not currently being marketed, they are in development at several pharmaceutical companies. When they do become available, it may be reasonable for phy...