Scientists grow heart tissue in Bioreactor
..., then these same cells can be manipulated to mimic the stages of breast cancer formation, and the model-related differences evaluated. "We have grown noncancerous human breast cells in the NASA Bioreactor," Richmond said. "Our observations suggest there is much to learn and va...How alcohol may harm your baby's brain
...ol dosages used in the study were high in order to mimic heavy alcoholuse during pregnancy. "Binge drinking is extremely important in terms ofproducing brain damage," said West. "For example, drinking four cans of beer inan hour can cause more damage than drinking six cans of beer over 12 hours." And eve...Misinterpretation of heart rhythm recordings may cause unnecessary treatments
...movement or poor skin-to-electrode contact. It can mimic various heart rhythmproblems, including ventricular tachycardia, a potentially life-threatening fastheart beat from the bottom chamber of the heart. The results of the studydemonstrate that when artifact is misdiagnosed as ventricular tachycardia,pat...Lack of sleep alters hormones, metabolism
...ine changes resulting from a significantsleep debt mimic many of the hallmarks of aging," said <AHREF="http://www.ccp.uchicago.edu/faculty/Cauter_Eve_Van/">Eve Van Cauter ,Ph.D., professor of medicine at the University of Chicago and director of thestudy. "We suspect that chronic sleep loss may no......g deterrents in adolescents and young adults." To mimic the "binge/crash" pattern of drug abuse in humans, Castner gave primates twice-daily injections of chronic amphetamine (AMPH), five days per week for six weeks. The AMPH dose ranged from 0.1 mg/kg to 1.0 mg/kg and was increased by 0.1 mg/kg every thr...... that exist in many plants that are used for food, mimic the effects of the hormone estrogen. As women near menopause, production of their natural estrogen declines, resulting in a variety of symptoms, including insomnia, vaginal dryness, mood swings, night sweats and hot flushes - a sense of warmth that b...UF study shows contemporary method accurately predicts cancer risk
... type of changes. "Basically what we are trying to mimic is very similar to the Pap smear for the detection of cervical cancer," said Masood, who presented findings from a UF study of FNAB in 869 patients with breast lesions. "The Pap smear, since its introduction, has reduced mortality from cervical cance...UT Southwestern scientists develop method of synthesizing antibodies
...ey set up a selection system to find peptides that mimic antibodies by binding to specific peptide epitopes, amino-acid compounds that can combine with antibodies. The scientists were interested in finding relatively small molecules, such as peptides, that could substitute for antibodies, which are crucial...Teasing out the early steps of neurodegeneration
...esearchers studying mice genetically engineered to mimic a human neurodegenerative disease called spinocerebellar ataxia type 1 (SCA1) have pinpointed abnormalities in gene expression that occur long before signs of the disease appear. The researchers believe that their discovery could lay the groundwork f...... unique to cancer," Danishefskyexplained. Vaccines mimic these components, training the immune system to see cancer cells as athreat. Several vaccines developed by Danishefsky's research team are about to enter Phase II and III clinicaltrials. The team plans to test whether they help prostate- and breast-c...Tobacco chemical protects against Parkinson's disease
...odents. Sold in the early l980s, MPTP was meant to mimic the effects of heroin. Addicts who took large doses suffered severe Parkinsonian symptoms. The naphthoquinone derivative protected the rodents against the toxic effects of MPTP, according to the researchers. The researchers have started a second rod...Castagnolis discover compound in tobacco that may protect against Parkinson's disease
...rug sold in the early 1980s. The drug was meant to mimic the effects of heroin, but addicts who took large doses of the synthetic heroin suffered severe Parkinsonian symptoms. Neal Castagnoli, then working at the University of California at San Francisco, was one of the scientists who determined what cause......ct in our bodies. Unlike the natural enzyme, the mimic of SOD is well suited for use as a drug because it...markable oxidative and kinetic stability. The SOD mimic used in this research is not a protein like the natural form, but instead is a specially constructed...Scientists develop polymers with nitric-oxide releasing particles
...itric oxide gas. The U-M polymers are designed to mimic human endothelial cells, which produce nitric oxide to relax blood vessels and inhibit blood coagulation. "Our goal is to reproduce the body's natural nitric oxide production system, which prevents clots from forming inside blood vessels," said Mar...UT Southwestern Nobel laureate leads bold project changing way scientists conduct research
...of a "virtual cell," a computer program that would mimic the function of a cell, Gilman said. "When we have a complete virtual cell, it can be used as a drug discovery engine to test drugs on the computer, rather than on cells or animals. It would be a wonderful way to understand what the optimal point wou...Study shows farm work appears to protect against breast cancer
...has been that DDT and certain other pesticides can mimic the effects of the female hormone estrogen and may promote breast cancer. Even during years when DDT was in use, from 1945 to 1972, scientists still found a protective effect for farming depending on the number of years worked, Duell said. Age, crop...NIH awards grant to MetaPhore Pharmaceuticals to study novel pain treatments
...y's patented metal-based compounds. The compounds mimic the body's primary defense mechanism against oxidative damage from the free radicals derived from oxygen known as superoxide. That defense mechanism in its natural state is a family of enzymes called superoxide dismutase (SOD). The research will s...Mouse provides clues about chronic pain
...ods of time. "That sustained response appears to mimic what happens in people who experience pain long after the painful stimulus has disappeared," says principal investigator Min Zhuo, Ph.D., an associate professor of anesthesiology and of anatomy and neurobiology. "So interfering with NR2B in humans mi......covered that a small molecule called adenosine can mimic the effects of nerve growth factor and brain-derived growth factor to prevent cell death in the nervous system, says Moses Chao, PhD, a neurobiologist at New York University. Such growth factors serve as survival agents for nerve cells, keeping them...Study: Ripped aortas kill often, but new knowledge may aid survival
..., altered consciousness, and limb paralysis, often mimic those of other cardiovascular conditions - resulting in delayed diagnosis. Only when patients reach an emergency room and undergo tests and scans can the cause be spotted. According to UMHS cardiology professor and ACC presenter William Armstrong, th...