Tag: "mimic" at medical news

Stanford computer model shows bypass surgery more cost-effective than stents

...l. The researchers found that the model did indeed mimic the costs and quality-of-life measures seen in the trial. Once the model was shown to work, they could change parameters based on how much a new procedure costs, what complications it prevents and how it improves patient outcome. "The model allowed u...

In lab studies, blocking expression of gene reduces invasion of deadly brain tumor cells

...tumors. Now, in laboratory experiments designed to mimic the environment of a brain tumor and its abnormal ...ls and brain endothelium, they were better able to mimic the situation as it would exist in actual patient tissue. Although scientists cannot say with certai...

Antidepressants decrease chronic pain by inhibiting TNF production in brain, UB researchers find

...al responses to pain, the researchers were able to mimic these cellular changes in the rat brain and produce the same changes that take place when naturally occurring chronic pain develops. By administering the antidepressant drug, they showed that the drug causes a decrease in TNF and an increase in nore...

Nicotine metabolite may improve memory, protect against disease

...uch studies suggest that nicotine -- or drugs that mimic nicotine -- may one day prove beneficial in the tr...imer's and Parkinson's diseases -- approaches that mimic the beneficial effect of nicotine on stress." In other studies, another doctoral student, Karem Al-...

National study seeks cause of baffling, fatal disorder called multiple system atrophy

...iology techniques, such as transgenic mice bred to mimic MSA, to investigate genetic factors and cell biology that contribute to the cellular malfunction. A progressive, degenerative neurological disorder with an average onset of 54 years of age, MSA is characterized by a wide range of symptoms, incl...

UB, military collaborate on design, testing of first drug to prevent noise-induced hearing loss

...exposed them to toxic continuous noise designed to mimic gunfire. As hoped, the antioxidant drugs kept inner-hair-cell damage to a minimum. "Those experiments proved our point," said Henderson, "but the results weren't applicable clinically. You can't inject drugs into the inner ears of humans." ...

Anthrax toxin inhibitor identified

...ptoms of the disease fever, cough and chest pain mimic colds and flu, early diagnosis is extremely difficult; as a result, some 90 percent of all cases of inhalational anthrax prove fatal. "Toxins act in two ways," adds BIDMC scientist and first author Benjamin Turk, Ph.D. "First, they cripple the cells ...

'Science' showcases research on forgetting

...ry so we can concentrate on our tasks at hand." To mimic the brain's process in the lab, Anderson and Gabrieli tested subjects using a procedure Anderson devised. Subjects first learned pairs of words such as ordeal-roach, steam-train and jaw-gum. Then they were given the first member of each word pair and...

Brief mail- and computer-generated interventions work best for problem drinking among young people

...as. "If designed well, web-based intervention can mimic some aspects of the clinical interview, in particular, the assessment, presentation of feedback, and encouragement to make healthier choices," he noted. "This is an area where more research is needed, but it shows great promise." The use of "motiva...

Research clarifies how Alzheimer's medicines may reduce interference with learning and memory

... either no drugs or the medicine glycopyrrolate to mimic the dry mouth produced when scopolamine is given. Glycopyrrolate is a synthetic anticholinergic that crosses the blood-brain barrier more slowly and incompletely compared with scopolamine. As expected, in the experimental group, memory for word-pa...

Protein helps immune system mount 'instant strike' against deadly flu viruses

... virus. Such vaccines are thought to more closely mimic a natural encounter with the flu virus and are more likely to induce peripheral immunity, which might deliver an instant strike against the virus as the infection begins. "When confronted by a deadly flu virus, the ability to attack it instantly, ...

Scientists find HIV-blocking protein in monkeys

...rmation to develop animal models that more closely mimic HIV disease. Matthew Stremlau, Ph.D., a member of Dr. Sodroski's team and lead author on the new paper, searched the rhesus monkey genome and isolated a stretch of DNA that encodes the TRIM5-alpha protein. In a series of experiments using lab-grown ...

Study supports new theory for nicotine's protective effect against neurodegenerative disorders

...ts of nicotine may also help us develop drugs that mimic the beneficial action of nicotine without its unwanted side effects." Nicotine mimics the neurotransmitter acetylcholine, a chemical messenger that is critical to communication between brain cells. Acetylcholine is the major neurotransmitter los...

Mouse model mimics real-world plague infection

...f Health. The scientists developed their model to mimic the natural transmission route of bubonic plague through the bites of infected fleas. The flea-to-mouse model provides a more realistic test setting than previously used methods, enabling a better assessment of a vaccine's ability to protect against ...

U of T researchers one step closer to creating oral insulin

...nship, they can work to designnovel molecules that mimic insulin's therapeutic properties. Other researchers included Ira Goldfine of the University of California,San Francisco, and U of T postdoctoral fellows Christopher Tan andLianhu Wei. U of T Innovations Foundation is managing thecommercialization of ...

Researchers testing compounds that may stop replication of T-cell leukemia virus

...ennison and other team members find compounds that mimic the HTLV-I protease's process of cutting amino aci...itors. For now, they are developing compounds that mimic peptides because they are easier to synthesize, Dennison explained. Eventually, they want to develop...

Exposure to food increases brain metabolism

...on swab dipped in water placed on their tongues to mimic the food-stimulation condition. Study participants were also instructed to describe, on a scale of 1 to 10, whether they felt hungry or desired food at the start of the study and at five-minute intervals for a total of 45 minutes. The researchers fo...

Second NIAID SARS vaccine candidate helps mice fend off SARS

...in, a vaccine based on this protein should closely mimic natural infection, notes senior author, Bernard Moss, M.D., Ph.D. Investigators inserted the gene encoding the S protein into a virus called modified vaccinia Ankara (MVA). Neither MVA nor the solitary gene from the SARS virus can cause disease. Ins...

Estrogenlike drugs may eventually help postmenopausal women with weight gain

...es removed (ovariectomized [OVX] rats) in order to mimic the decline in sex steroids that occurs at menopause, have found that OVX rats eat more and gain weight more rapidly than sham-opEαted control rats. Estrogen replacement reduces both the increased food intake and the body weight gain of the OVX ...

Space solutions for health

... immune system and sensory disorientation, closely mimic the way our body degrades as it ages or is kept inactive. The combination of an increasingly older population and diseases associated with inactivity is causing one of the largest epidemics the world has ever witnessed. Several hundred million of p...

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(Date:4/18/2014)... This news release is available in French . ... breakthrough could revolutionize surgical practice and regenerative medicine. A ... Molle et Chimie (CNRS/ESPCI Paris Tech) and Didier Letourneur ... and Paris 13), has just demonstrated that the principle ... used in vivo to repair soft-tissue organs and tissues. ...
(Date:4/17/2014)... targets that could be used to provide relief ... London made the discovery when researching how pain ... body. , Dr Marzia Malcangio said: "We have ... and our findings could help chemotherapy patients who ... side effect of some chemotherapy drugs (such as ...
(Date:4/17/2014)... AURORA, Colo. (April 17, 2014) Two recent ... Medicine researcher and colleagues may help scientists develop ... virus, Yellow fever, Japanese encephalitis and other disease-causing ... of biochemistry and molecular genetics at the School ... the Howard Hughes Medical Institute, and colleagues recently ...
(Date:4/17/2014)... Doctors who treat patients with a severe ... face an agonizing treatment decision. , The drug ... help relieve shortness of breath. But some patients ... cause potentially fatal complications following transplantation. , "It,s ... medical director of Loyola University Medical Center,s LAM ...
(Date:4/17/2014)... University School of Medicine (BUSM) have discovered that ... an experimental model. The findings, reported in the ... , may lead to more effective treatments for ... of the leading causes of illness and death ... impact by limiting the productivity of workers and ...
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