Clot-busting drugs may help detect potentially deadly leg clots
... be they have confounders, such as antibodies that mimic d-dimers," says Dr. Robinson. Adding tPA or some other clot-dissolving drug right before the test may clear up those positives and negatives, he says, hypothesizing that measuring the difference between the standard and the new 'provoked' d-dimer tes...Changing chemistry helps explain estrogen threat to the heart
...t in which researchers will use different drugs to mimic aging, drugs that knock out L-arginine and tetrahydrobiopterin, to try to create an aged artery and restudy estrogen's impact. "Estrogen is so powerful; it affects every system in your body. We are looking with tunnel vision at its effect on blood pr...Philanthropist Paul F. Glenn launches labs for aging research at Harvard Medical School
...eld have been pursuing the molecular pathways that mimic calorie restriction. In the summer of 2003, Sinclair's team showed in a paper published in Nature that a compound found in red wine called resveratrol could stimulate this pathway in yeast cells. The yeast cells lived as much as 60 percent longer, a...Chemical decoy shows promise for slowing Alzheimer's by acting as decoy
... star-shaped polymers with surface sialic acids to mimic the molecules found on brain cell surfaces. Using a human neuron-derived cell line, the researchers showed in test tube studies that addition of the polymer serves as an effective "decoy" for attracting the circulating beta amyloid proteins away from...