Transcranial Magnetic Stimulation Enhances Short-Term Brain Plasticity
...blocking nerve signals to the brain andtemporarily mimicking what occurs after amputation. The loss of normal signalscaused the brain to reorganize. When the researchers applied TMS to the plasticcortex, or the part of the brain that was undergoing reorganization because ofthe tourniquet, the brain?s respons......t inhormone-naïve prostate cancer patients by mimicking the female hormone,estrogen. The compound may contain other active anti-cancer ingredients becauseit also lowered PSA levels in men in the study whose tumors have becomeresistant to hormonal treatments. In their initial stages of growth, prostate can......estrogen receptormodulators (SERMS). SERMS work by mimicking the effects of estrogen in someparts of the body--for example SERMS mimic the positive effects of estrogen on awoman's bones and cholesterol levels--while inhibiting estrogen's "bad" effectson a woman's risk of breast cancer. One of the most signific...Psychologist finds low-cost methods to prevent pharmacy mistakes
...eal pharmacy. The lab has been very successful in mimicking what happens in a real pharmacy." Grasha's long-term goal is to develop a pharmacy simulator where working pharmacists could come and work the same way airline pilots use flight simulators....Altered mice provide model of rare childhood disease, NIH and Georgetown researchers find
...fer, PhD, created the mice with the genetic defect mimicking the human disease, while the Georgetown researcherswho in addition to Ebert included Bjoern Knollmann, MD, PhD, Assistant Professor of Clinical Pharmacology and Michael Franz, MD, PhD, Professor of Pharmacologystudied the cardiac abnormalities. They ...Cycled light promotes growth in pre-term infants
...ss. "Cycled light establishes a day/night rhythm, mimicking the circadian rhythm cues that are established for full-term babies in the womb," said Brandon. "We know adults rely on circadian rhythms for health, growth and development, and pre-term babies grow within a rich circadian environment provided by the...Spiral scan sees stroke blockage more clearly
...igraine headache, or a drastic drop in blood sugar mimicking a stroke. About 600,000 Americans suffer a first or recurrent stroke each year and about 167,000 of them die. The two major types of stroke are ischemic, caused by a blood clot that blocks a vessel and prevents oxygen-rich blood from reaching a po...Mastiffs could aid treatment of retinitis pigmentosa
...he dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa." Although this gene defect leading to RP in humans was discovered in 1990 -- and could be simulated by genetic manipulation in mice, rats, fruit flies and pigs -- vision researchers had been searching for a lar...A helping hand: Healthy arm helps retrain stroke-impaired arm
...where the unaffected arm helps the affected arm by mimicking its movement. The second group had active neuromuscular stimulation and unilateral movement therapy on the affected arm only. The third group, "the controls," had physical therapy on the affected limb without the aid of electrical stimulation or b...With cues from nature, scientists develop new method to purify drugs
...art of the increasing trend toward biomimetics, or mimicking biological solutions in industrial processes, the researchers' ideas came from biological chemistry. Martin said the Finnish researchers recognized that antibodies, which identify and attack pathogens in the body, are good at identifying and attachin...Bleach-producing enzyme found to modulate blood vessel dilation during inflammation
...essure conditions from developing. Drugs aimed at mimicking this enzymatic activity may be useful for treating systemic hypotension during septic shock. Alternatively, drugs aimed at blocking the activity of myeloperoxidase may be useful for treating chronic vascular diseases, such as atherosclerosis, which ...Sleep and sedation controlled in same brain centre, say scientists
...hetics, pentobarbital and propofol induce sleep by mimicking the natural process of falling into a deep sleep. Using behavioural studies and molecular imaging techniques in rats, the team of basic scientists and clinicians found that the sleep-inducing action of anaesthetics is localised to a small area of th...UT Southwestern researchers find clue to understanding tolerance to drugs of abuse
...sfer to deliver and overexpress CREB locally, thus mimicking the CREB hyperactivity seen after the delivery of drugs of abuse or exposure to stress. The mice were then tested for their sensitivity to rewards, such as morphine or sucrose, as well as for their sensitivity to anxiety-causing negative situations ...Foot pressure device may stamp out muscle loss
...rick a free-floating astronaut's nervous system by mimicking the pressure one's feet feel while standing on the ground. Astronauts on board the Russian Space Station MIR wore Layne's first boots, and data collected from those flights indicated that continuous foot pressure from the boots resulted in enhanced m...Comparison of HRTs finds progesteron
...and the progesterone for 12 days per 28 day cycle, mimicking a menstrual cycle with bleeding near the end of the progesterone phase. A continuous HRT regimen uses the same dose of estrogen and progesterone every day and is expected to cause less bleeding. Excess bleeding was considered to be any bleeding on a ...Mimicking brain's 'all clear' quells fear in rats
...frontal cortex, extinguishes this fear response by mimicking the brain's own "safety signal." They report on t... for extinction was strengthened by experimentally mimicking the safety signal. Since the prefrontal cortex is known to project to the amygdala, a hub of fear ...UCB's pharma sector announces promising first results of a new antiepileptic drug candidate
...ing seizure severity and duration in animal models mimicking both partial and generalised epilepsy. Tolerability When comparing the therapeutic index of ucb 34714 against referenced AEDs, it was found to have a wide safety margin in in vivo models of chronic epilepsy. Disease modifying properties The p...Study shows melatonin supplements may make standing a hazard for the cardiovascular-challenged
...amber, a device that reduces pressure to the legs, mimicking the effect of a person standing up. Ray used microneurography to record the sympathetic nerve activity to the blood vessels of the muscles. Sympathetic nerve activity starts a chain reaction that causes the blood vessels to constrict, increasing bloo...2003 winners of Collegiate Inventors Competition announced in NYC
...se insulin in a synthetically-created environment, mimicking cell structures found in a healthy pancreas. Her work has the potential to aid those who suffer from type 1 diabetes. A native of Houston, Shen is a student at Harvard working in unique collaboration with her advisor, Carlos Semino of the Massachus...Key feature of HeartMate II heart assist device developed at University of Pittsburgh
...was among the first axial flow devices; instead of mimicking the heart's pumping mechanism, the Nimbus pump was designed as a much smaller rotary device that results in continuous flow of blood. In 1996, Thermo Cardiosystems Inc. acquired Nimbus, at which time the device became known as HeartMate II. In 2001, ...