Cord blood stem cells save children with Hurler's syndrome
...bolic disease die by the age of 6 because they are missing an important enzyme, alpha-L-iduronidase, which le...he ability of cord blood stem cells to provide the missing enzyme and thereby halt the progressive organ deterioration in these children. Stem cells in cord bl...Cancer gene therapy news backgrounder: New ideas fuel next generation gene therapy research
...should disarm cancer. Such treatment would replace missing or faulty genes that keep cell growth in check, or...ry, had more success. He found that an abnormal or missing p53 gene in lung tumors could be successfully replaced in experimental animals. The p53 gene, which ...Major study: Bioartificial liver reduces mortality by 44 percent in acute liver-failure patients
...ibers, the pig liver cells detoxify it and replace missing nutrients." Each treatment is completed in about six hours, and the benefits last about 24 hours. In most cases of acute liver failure, a series of treatments may need to continue for only a few days or several weeks. "Typically, within that time the...Multiple factors affect psoriasis treatment compliance
... researchers also found that the major reasons for missing treatment were drinking alcohol, being fed up, forgetfulness, and being too busy. "Because of the instinctive aversion to skin disease and because of the skin's function as a major organ of social and sexual communication, it is understandable that s...Office spirometry significantly improves early detection of COPD
... only patients with symptoms of COPD may result in missing an important number of people with obstructive lung disease," said Dr. Buffels. "As shown in our study, office spirometry nearly doubled the number of known cases of COPD in our target patient population, which reinforces the need for spirometry tes...Missed alcohol diagnoses in hospital patients
...tment as needed. "This study indicates that we are missing many opportunities to identify and treat hospitalized individuals who have alcohol problems," said NIAAA Director Ting-Kai Li, M.D. "By routinely screening all hospital patients who report current alcohol use we could help many individuals avail the...Duke scientists overcome immune resistance in dendritic cell vaccines for cancer
...f the study. "Our study highlights what element is missing in dendritic cell vaccines that prevents them from activating the immune system, and we've shown how to insert that element." The major problem, said Yang, is that cancer cells are wily invaders, camouflaging themselves as part and parcel of the body...American Thoracic Society Journal news tips for April 2004 (first issue)
...ase, occurring in 1 in every 2,500 white babies. A missing gene leads to the production of very sticky secretions which, among other organs affected, can clog the airways of the lung.) The investigators point out that CF patients have evidence of airway infection, inflammation, and products from tissue dest...Genome sequence reveals leaner, meaner intestinal parasite
...hich there is currently no effective treatment--is missing key structures normally found in similar parasites...N, and his team discovered that Cryptosporidium is missing two organelles commonly found in related protozoan parasites. Gone is the apicoplast, a cellular com...Key to proper blood vessel growth in eye and ear discovered
...ted the investigation by examining changes in mice missing Frizzled-4, which is defective in one form of fami...he eye and ear as seen in an earlier study of mice missing Norrin, which is faulty in Norrie [sic] disease. Both diseases are characterized by problems in bloo...Researchers to pinpoint relationship between obesity-associated diabetes and heart disease
...set off inflammation. Inflammation may provide the missing link to heart disease." The researchers will examine the inflammatory process, particularly what triggers it and what inhibits it. Previously, they demonstrated that in lean people, elevated free fatty acids cause insulin resistance and start the pro...American Thoracic Society Journal news tips for March 2004
...se, occurring in 1 in every 2,500 white babies. A missing gene that regulates chloride and sodium transport across cell membranes causes problems, leading to dehydration and the production of very sticky secretions. In CF, the mucus-producing glands of the lung produce thick, abnormal secretions that clog ...Two better than one where lowering blood pressure is concerned
...essure lowering drug, meaning that many people are missing out on what we consider the best standard of treatment in this country. The guidelines, authored by the Guidelines Committee of the British Hypertension Society, also suggest a simple 'AB/CD protocol' to help doctors combine the different classes of ...Innovative reconstructive surgery improves appearance, outcomes for skin cancer patients
...t of the body to another to reconstruct damaged or missing tissue. Although free tissue transfer surgery has been around since 1991, only a few surgeons perform this type of reconstruction. OHSU is the only center in Oregon to offer this expertise. Wax and his colleagues recently published a study showing th...Crystal methamphetamine use increases HIV risk
...on, HIV-positive meth users on HIV medications are missing more doses and are likely contributing to the spread of drug-resistant strains of HIV, said Dr. Urbina. Among HIV-positive patients not receiving ART, meth use may increase the risk of developing HIV dementia, a condition associated with reduced mot...Teenagers with cancer are missing out on vital services
...al. "Concerns were widely expressed about children missing out, but from these figures it looks apparent that the worst victims are the teens and young adults. "The threat of a reduction in clinical trials from the current EU Directive is being tackled here in Parliament". "Currently, in my constituency, Nor...Contraception study supports convenience, simplicity
...ith the Pill. Inconsistent or incorrect use, i.e., missing one or more pills per cycle, can increase the risk...acy (p = .007) than imperfect dosing cycles, i.e., missing a dose and doubling up the next day. ORTHO EVRA is indicated for the prevention of pregnancy. ORT...Targeting cell fusion as possible way to repair organs, deliver cancer vaccines
...kill each other has been known for some years. The missing element has been a way to direct fusion partners to exploit this tendency and use it as a basis for anticancer treatment. The ability to target fusion partners is important. If the wrong cells fuse, then healthy cells -- instead of cancer -- can ...Cord blood cells proven to differentiate into heart muscle and brain cells
...called Sanfilippo Syndrome B, in which the body is missing a critical enzyme needed to break down complex sugars in various cells. As sugar byproducts accumulate in vital organs such as the liver, heart and brain, cells become damaged and die. Duke physicians had observed that children with these rare metabo...'Camera pill' promising for diagnosis of small bowel disease
...ents (21 percent). "We wanted to see what we were missing or not missing with standard radiology techniques," said Dr. Hara, principal author of the study. "The information ...