Smart virus eliminates brain cancer in animal experiments
...m triggering DNA replication. If the Rb protein is missing or non-functioning, a cell can replicate itself over and over, resulting in the development of a tumor. In normal cells, the Rb protein also prevents a virus that enters a cell from replicating. Adenoviruses, however, counteract that defensive measu...Enzyme found in blood vessels likely target to treat lung injury
...l. Watterson genetically engineered mice that are missing the gene that codes for MLCK 210. The researchers exposed mice lacking MLCK 210 to a bacterial toxin that causes tissue injury as a result of severe infection. The MLCK 210 knockout mice are less susceptible to acute lung injury and also showed signi...Racial differences in pain treatment found
...ICAGO African Americans may be disproportionately missing out on effective treatment for their chronic pain -- from arthritis to backaches -- and as a result suffering outsize effects on their ability to work, play and enjoy life, a new study finds. New research results on pain differences between blacks an...The common cold coughs up $40 billion annual price tag
...doesn't usually consider the costs associated with missing a day of work due to illness or having to stay home to take care of a sick child. Not surprisingly, lost work drives most of the cost." The study found that Americans spend $2.9 billion on over-the-counter drugs and another $400 million on prescrip...U.Va. team identifies gene that could halt spread of cancer
... suppressor gene, the U.Va. researchers "replaced" missing RhoGDI2 genes in human metastatic cancer cells that did not manufacture the gene on their own. "We replaced the gene in the most aggressive cell lines we had in the lab," Theodorescu said. "The first thing we noticed was that the cells grew normally....Computers prove to greatly reduce prescription errors
...criptions that decreased errors related to dosing, missing information, incorrect information, legibility and ordering of drugs that weren't available. These types of errors require a pharmacist to track down the prescriber to clarify before the prescription can be filled. Although this occurs infrequently,...Free smoke alarm programmes are failing
...g when tested 15 months later. Forty per cent were missing or had been disabled by tenants. Ionising smoke alarms with long life lithium batteries were most likely to remain functioning. Although the government recommends that local authorities install battery powered smoke alarms in all their properties, th...New study documents burden of irritable bowel syndrome for U.S. sufferers
...y findings. Of IBS patients who work, 39% reported missing work and decreased productivity an average of 6 days and 16 days respectively, and decreased productivity at home an average of 16 days in the last three months. Ninety percent reported limited ability to perform important daily activities due to th...Gene therapy success in the laboratory buoys hope for Parkinson's disease
...ase. "It's not just inserting a replacement for a missing or mutated gene as a treatment for a genetic disorder," says Michael Oshinsky, Ph.D., research assistant professor of neurology at Jefferson Medical College of Thomas Jefferson University in Philadelphia and part of the team reporting its results Oct...Duke and federal government partner to create innovative health care model
...ack, stroke or developing diabetes. "What has been missing in America is a health system designed to facilitate the ability of individuals to promote their health by being more involved in their care and to help them focus on preventing illnesses most likely to cause them great harm. We need to get physician...Chemists show proteins behave differently inside cells than they do in water solutions
...studying them in water, but this work shows we are missing important observations by looking at them just in water or other solutions," said Dr. Gary Pielak, professor of chemistry and lead author of the study. "Our work demonstrates that we need to study them under the conditions they are found in inside th...Memorial Sloan-Kettering scientists uncover function of BRCA2 protein
...ss called homologous recombination -- in which the missing DNA is copied from another part of the cell. "We are now a step closer to understanding this particular type of inherited breast and ovarian cancers," Dr. Pavletich said. Mutations in the BRCA2 gene have been implicated in hereditary breast and ovari...FINAL ALERT: RPB Science Writers Seminar in Eye Research to be held in Washington, DC Sept. 22-25
...on loss from AMD and diabetic retinopathy. What's missing though is a sure-fire way for getting the drugs to where they need to go -- the retina and choroid -- repeatedly and in sufficient doses. A new delivery system shows promise of filling that gap. Now in animal trials, it calls for pumping drugs dire...The Lancet Neurology press release
...oth the hypocretin-1 and hypocretin-2 peptides are missing in the brains of patients with narcolepsy. In this month's TLN, Shahrad Taheri and Emmanuel Mignot discuss the current knowledge on the role of genetic risk factors in sleep disorders, in particular circadian disorders, narcolepsy, restless-legs synd...School program reduces risk of obesity, disease in border community
... for the observed improvements. Baseline data were missing from some schools, they note, and other influences could have been at work. Nevertheless, they said the lack of improvement in physical activity levels and increase in fat content of school meals at the non-CATCH schools during the same time period s......them beautiful." Think of a certain facial mole, a missing tooth....Understanding genetic cancer risk might not help smokers kick the habit
...individuals with lung cancer are more likely to be missing the GSTM1 than matched controls, and it has been e...imated that 35 percent of African Americans may be missing the GSTM1. GSTM1 is responsible for creating an enzyme involved in detoxifying a number of environm...Muscle stem cells show promise against muscular dystrophy in mouse model
...at can improve muscle regeneration and deliver the missing protein dystrophin to damaged muscles in a mouse muscular dystrophy (MD) model, according to a study supported in part by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The research, carried out by Johnny...Common diabetes drug causes arteries to spasm, endangering heart
...of females had died. The spasms were caused by the missing receptor, the same one that is targeted by the sulfonylureas. Sulfonylureas induce the pancreas to release insulin by blocking this receptor. Blocking the receptor inhibits a potassium channel on the cell surface. When this channel is closed, pota......Many people grew up with animals and feel they are missing something. The research shows what we have long suspected - the availability of pets fills a void."...