Tag: "mit" at medical news

TB Alliance announces new drug discovery program with GlaxoSmithKline

... ... ...Teleconference to provide overview on launch of broad discovery portfolio to improve the treatment of tuberculosis (TB). The program significantly enhances the TB drug pipeline by adding several novel classes of compounds that use new mechanisms of action. Briefings from the TB Alliance on status of TB drug pipeline and discussion with GlaxoSmithKline, patient and public health group...

GlaxoSmithKline receives unanimous favorable recommendation by FDA Advisory Committee for Boostrix

PHILADELPHIA, PA, March 15, 2005 GlaxoSmithKline (NYSE: GSK) today announced that its booster vaccine candidate, BoostrixTM [Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed (Tdap)] received a unanimous favorable recommendation from the Vaccines and Related Biological Products Advisory Committee of the U.S. Food and Drug Administration (FDA). Currently, there...

SAM on the favorable recommendation by FDA Advisory Committee for Boostrix

BLUE SPRINGS, MO March 15, 2005 The Society for Adolescent Medicine supports the unanimous favorable recommendation of the Vaccines and Related Biological Products Advisory Committee of the U.S. Food and Drug Administration (FDA) regarding the development of a vaccine to prevent the occurrence of pertussis in adolescents. We believe that the development of this vaccine will further the health...

CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide

A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. This finding, by researchers at St. Jude Children's Research Hospital, is currently published in the online edition of Oncogene. ...The renegade CK2 protein keeps the tumor alive and growing by desensiti...

Female sex hormones play a vital role in defense against sexually transmitted diseases

Hamilton, Ontario (February 16, 2005) Two McMaster University studies, to be published in the Journal of Virology, show that sex hormones have a profound effect on susceptibility of female mice to the herpes simplex virus, type 2 (HSV-2 ), one of the most common sexually transmitted diseases. ...... Charu Kaushic, assistant professor and supervisor of the studies, says the implication of this w...

Miniaturized lab permits saliva screening on the go

WASHINGTON A team of scientists and engineers led by Daniel Malamud at the University of Pennsylvania has developed a robust means of analyzing oral samples. They believe their work will lead to a kit, not much bigger than a credit card, which could detect exposure to a variety of substances, from narcotics to anthrax to common bacteria and viruses. Their plan would increase ease of detection...

AstraZeneca submits regulatory application in Europe for use of Atacand(R) in heart failure

Mlndal, Sweden, 7 April AstraZeneca today announced the submission of a regulatory application in the European Union (EU), as part of the Mutual Recognition Variation Procedure to obtain a new indication for Atacand (candesartan cilexetil), its angiotensin II type 1 (AT1) receptor blocker, for use in the treatment of heart failure. The UK acts as the RMS (Reference Member State). Further filings...

Carnegie Mellon interactive-video DVD helps teens avoid sexually transmitted diseases

PITTSBURGH--Sexually active teenage girls who viewed an interactive sex education DVD created by researchers at Carnegie Mellon University were more likely to become abstinent than girls who did not see the DVD, according to a study of 300 adolescent girls in the Pittsburgh area. The study will be published this fall in the journal "Social Science and Medicine."...... The DVD, "What Could You Do?...

Women suffering from anorexia are 50 times more likely to commit suicide

BOSTON, Mass. - In a study of suicidal behavior of 246 women with eating disorders over a span of 8.6 years, Debra L. Franko, an associate professor of counseling psychology at Northeastern University's Bouv College of Health Sciences, and her colleagues at Massachusetts General Hospital (MGH), found that women with anorexia nervosa are 57 times more likely to commit suicide than the expected ra...

New study tests amitriptyline for painful bladder syndrome

A new study will test an FDA-approved antidepressant for its potential to alleviate bladder pain for which there is no known cause and no effective therapy. Thousands, if not millions, of patients may benefit. The study is funded by the National Institutes of Health (NIH)....... Ten medical centers in the United States and Canada are recruiting adults newly diagnosed with either painful bladder s...

Immediate access to antibiotics stems spread of sexually transmitted diseases

In an editorial to be published in The New England Journal of Medicine, researchers at Johns Hopkins offer their support for a study which shows that providing faster, more direct access to antibiotics for partners of newly infected patients reduces re-infection rates and spread of sexually transmitted diseases, such as gonorrhea and Chlamydia, compared to standard practice. ......In the study, t...

Using the internet's power and anonymity to reduce problem drinking

Computers, and the internet, have become an integral part of North American life, whether located at home, school or the workplace. At least 80 percent of internet "surfers" in the United States have reportedly used the internet to access health information. Symposium proceedings published in the February issue of describe several alcohol interventions based on in-person brief motivational i...

Murder, eyewitness identification and the limits of human vision

Geoffrey Loftus' latest research reads more like a murder mystery than a scientific paper.... The University of Washington psychologist's new study opens with a savage beating and murder on the streets of Fairbanks, Alaska. It features cameo appearances by Julia Roberts and other celebrities. It ends with the conviction of two men based on the eyewitness identification of the defendants from a d...

Northwestern Memorial Hospital receives $10 million commitment to support preeminent heart program

Northwestern Memorial Hospital today announced that Neil G. Bluhm, a prominent real estate developer, and his family have committed $10 million to the Northwestern Cardiovascular Institute, which has been renamed the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital. The Bluhm Cardiovascular Institute, which launched in April of 2004 with the arrival of renowned cardiothoracic sur...

HIV-infected parents report limiting physical contact with their children

CHICAGO Over one-fourth of HIV-infected parents reported avoiding certain physical interactions, like hugging or kissing, with their children due to a fear of transmitting the disease or of contracting an infection from them, according to an article in the February issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. ......Of adults receiving care for human i...

Parents comfortable with vaccination for sexually transmitted infections for adolescent children

CHICAGO Parents are generally accepting of the hypothetical scenario of vaccinating their adolescent children against infection, whether the infection is sexually transmitted or not, according to a study in the February issue of The Archives of Pediatrics and Adolescent Medicine, one of the JAMA/Archives journals. ......Several vaccines for the prevention of sexually transmitted infections (STIs...

$10-million study explores men's role in transmitting HPV

Tampa, FL (Feb. 1, 2005) In the largest grant ever to a Cancer Control and Prevention researcher at the H. Lee Moffitt Cancer Center & Research Institute, the National Institutes of Health awarded $10 million to Anna Giuliano, Ph.D., to help determine men's roles in spreading the human papillomavirus (HPV), which causes deadly cervical cancer in women.... ...The grant is the largest of its kind...

Moving admitted ER patients into inpatient beds faster could significantly increase hospital revenue

WASHINGTON, DC--By more efficiently moving admitted emergency department patients into inpatient beds, emergency medical staff could care for more people, which could greatly increase hospital revenue and offset losses from the charity care it provides, according to a study to be published December 20 as an early online release by Annals of Emergency Medicine. (Cost of an ED Visit and Its Relatio...

ESA presents space solutions at post-Kyoto climate summit

The 1997 Kyoto Protocol of the United Nations Framework Convention on Climate Change aims to lessen the effects of climate change by setting targets for industrialised countries to reduce emissions of heat-trapping 'greenhouse' gases including carbon dioxide. Fossil fuel burning and land use change since the start of the Industrial Revolution has led to the highest level of atmospheric carbon dio...

Stem cells of limited use for cardiac muscle repair

New evidence suggests that a promising investigational treatment for patients with damaged hearts -- using adult stem cells to regenerate heart tissue -- may not work as planned. In the December 2004 issue of the Journal of Clinical Investigation, researchers from the University of Chicago show that although stem cells derived from bone marrow can find their way to areas of damaged heart muscle,...

NSAIDs are of limited use for osteoarthritis

Patients with knee osteoarthritis should avoid long term use of non-steroidal anti-inflammatory drugs (NSAIDs), say researchers in a study published on today. ...... Current guidelines recommend the use of oral NSAIDs in the treatment of knee osteoarthritis and they are used regularly by half of all patients with painful osteoarthritis....... Researchers in Norway analysed 23 trials to estimate...

Limitations of current evaluation techniques for the cost-effectiveness of treatments

Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Pharmaceutical and surgical therapies for PD are available and can alleviate the symptoms and complications. Unfortunately, despite these therapies, the disease relentlessly progresses. A new study in the journal Value in Health presents a detailed overview of the current decision-analytic models used to evaluate th...

Percutaneous edge-to-edge mitral valve repair shows favorable preliminary results

(Philadelphia, PA and New Orleans, Louisiana) The Hospital of the University of Pennsylvania (HUP) is participating in a nationwide clinical trial of a new valve repair device that could replace major heart surgery in some patients. A tiny clip delivered by a catheter and deployed in the heart to repair a malfunctioning and leaking mitral valve is building a favorable safety and feasibility p...

Astronauts submit first medical research paper from space

OAK BROOK, Ill., Nov. 8, 2004 The first medical research paper submitted from the International Space Station (ISS) was published online today by the journal Radiology. The report documents the first ultrasound examination of the shoulder performed under the microgravity conditions of space flight....... Members of Expedition 9 crew aboard the ISS completed the study as part of the Advanced Diag...

GSA bestows Robert W. Kleemeier Award to University of Texas Health Science Center's Smith

he Gerontological Society of America has chosen Dr. James R. Smith of the University of Texas Health Science Center as the 2004 recipient of the Robert W. Kleemeier Award. This distinction is given annually to a GSA member in recognition for outstanding research in the field of gerontology.... ...The award presentation will take place at GSA's 57th Annual Scientific Meeting, which will be held fr...

UCSF receives $21 million NIH contract for sexually transmitted infection research

The National Institutes of Health has awarded $21 million to the UCSF Women's Global Health Imperative to conduct clinical trials for new treatments as well as prevention and diagnostic products for non-HIV sexually transmitted infections (STI)....... The trials will cover a full range of treatments and products, including microbicides, which are pathogen-killing topical creams or gels, and vacci...

Limiting angioplasty to experienced hospitals will not reduce access to care

DURHAM, NC Standards of volume that limit angioplasty procedures to more experienced hospitals and physicians will not require most patients to travel longer distances for care, according to a new study by researchers at Duke University Medical Center and Duke's Fuqua School of Business. The findings should allay concerns about the effects of such standards on access to care for heart patients l...

Siberian forest fires partly to blame for Seattle area violating EPA ozone limit

Smoke from giant Siberian forest fires pushed one measure of Seattle's air quality past federal environmental limits on at least one day in 2003, new research shows....... And the rapidly changing climate in northern latitudes makes it likely such fires will have increasingly serious ramifications for air quality all along the West Coast of North America, said Dan Jaffe, an environmental scienti...

Storage limits on our visual hard drive

NASHVILLE, Tenn.--Scientists have discovered the region of the brain responsible for the old adage, "out of sight, out of mind."... ...The amount of information we can remember from a visual scene is extremely limited and the source of that limit may lie in the posterior parietal cortex, a region of the brain involved in visual short-term memory, Vanderbilt psychologist Ren Marois and graduate s...

Computerized prescriber order entry systems may have limited impact on patient harm

Computerized prescriber order entry (CPOE) systems decrease medication error, but they may not decrease patient harm due to medication error, according to the results of a study conducted at Northwestern Memorial Hospital and published this week in Archives of Internal Medicine. ... ..."Medication errors are the single most common serious adverse event that occurs in hospitalized patients,...

Alcohol limit for drink driving should be much lower

The alcohol limit for drink driving should be much lower, argues a researcher in this week's BMJ....... In the United Kingdom, United States, Canada, South Africa, and Sri Lanka the legal blood alcohol limit is 0.08 mg per 100 ml. ...... This is too high as there is clear evidence that driving skills deteriorate and the risk of becoming involved in a crash increases from a blood alcohol concentra...

MIT reports new insights in visual recognition

CAMBRIDGE, Mass.--MIT scientists are reporting new insights into how the human brain recognizes objects, especially faces, in work that could lead to improved machine vision systems, diagnostics for certain neurological conditions and more.... ...Look at a photo of people running a marathon. The lead runners' faces are quite distinct, but we can also make out the faces of those farther in the dis...

Top medical and scientific societies commit to providing free access to research

(March 16, 2004) Washington, DC Representatives from the nation's leading not-for-profit medical/scientific societies and publishers have announced their commitment to providing free access and wide dissemination of published research findings. Their commitment was conveyed today by the American Academy of Pediatrics, American Cancer Society, the American Diabetes Association and others, during...

2004 Pulp Biology Research Award to Tony Smith

Honolulu, Hawaii...Professor Anthony J. (Tony) Smith, Professor of Oral Biology and Assistant Director, School of Dentistry of the University of Birmingham, United Kingdom, has been selected the 2004 recipient of the Pulp Biology Research Award from the International Association for Dental Research (IADR), convening here today for its 82nd General Session. ......Dr. Smith has made an invaluable...

Data shows new drug, rimonabant, helps smokers quit while limiting post cessation weight gain

Cincinnati, OH, March 9, 2004 - C Researchers at the University of Cincinnati College of Medicine presented results of one of the largest smoking cessation trials ever conducted in the United States, STRATUS-US (STudies with Rimonabant And Tobacco USe). The findings show that a new drug, rimonabant, doubled the odds of quitting smoking compared with placebo, markedly reduced post-cessation weigh...

St. Jude Medical announces PAVE and DINAMIT clinical trial results

ST. PAUL, MN, March 8, 2004 -- St. Jude Medical, Inc. (NYSE:STJ) announced today the results of the PAVE (Post AV Nodal Ablation Evaluation) and DINAMIT (Defibrillator IN Acute Myocardial Infarction Trial) clinical studies at the American College of Cardiology's (ACC) Annual Scientific Session 2004 in New Orleans, Louisiana. Both studies were sponsored by St. Jude Medical.... ...The data f...

Young people prone to type 2 diabetes exhibit alterations in mitochondrial activity

Researchers at Yale have found that decreased activity in muscle mitochondria, the powerhouses of the cell, may be a major factor in the development of type 2 diabetes in young, lean offspring of parents with the disease. ... ...They demonstrated a potential mechanism for the accumulation of fat in muscle cells of young, lean, insulin-resistant children of parents with type 2 diabetes by compar...

Scientists identify cell defects that limit immune system's impact on late-stage tumors

LOS ANGELES (Jan. 21, 2004) Although vaccines developed to help the immune system fight tumors appear to have an impact against early-stage tumors, they have little if any success in slowing the growth of tumors in later stages. Now researchers writing in the Feb. 1, 2004 issue of identify abnormalities in the immune system's T cells, provide insight into their origin, and describe how these d...

Malpractice reform must focus on reducing patient injury, not just limiting awards

New York City, January 5, 2004--Reducing medical injury is essential to solving the current medical malpractice crisis, and physicians must play an active role in developing and implementing systems to improve patient safety, according to an article published in the January 6th issue of Annals of Internal Medicine.... ...In "Malpractice Reform Must Include Steps to Prevent Medical Injury," Stephe...

Antibiotic resistant bacteria frequently transmitted between intensive care patients

Bacteria with resistance to multiple antibiotics will become more common in intensive care units unless hospitals improve their hygiene standards. Research published in Critical Care this week shows that there is an "unexpectedly high" level of transmission of bacteria between intensive care patients. ...... Intensive care patients are especially vulnerable to picking up infections in hospital, d...
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