UB scientists discover role of melatonin in bone formation
...rs, a characteristic that makes these cells a good model forhuman osteoblasts. While the mechanism that allows melatonin to have an effect on boneformation is still unclear, the UB researchers hypothesize it may involve anintracellular second messenger called cyclic AMP. "We know that rece...UCSF to attack HIV at molecular level with new center and $7 million in state funds
...ly1980s, UCSF is known throughout the world as the model forstudying the disease in all areas-basic science, treatment approaches,prevention strategies, and policy issues. Greenspan and Volberding are two UCSF faculty who have been with the UCSF AIDSprogram from its earliest days when the first patients we...Parents serve as models for adolescents' health behavior
Adolescents tend to model their parents' behavior in eating, smoking, andpracticing healthy and unhealthy lifestyle habits, according to researchconducted at Iowa State University, Ames. "Adolescents who are constantly exposed to parents' health-risk behavior, suchas poor eat...Study suggests some unruptured aneurysms do not need treatment
... the ISUIA study. The UCSF researchers developed a model in which they projected the health outcomes and financial costs associated with hypothetical patients with unruptured aneurysms who either received or did not receive treatment. Those receiving treatment either underwent the standard procedure in wh...UCSF finding could lead to a new class of painkillers
... commonly used by the pharmaceutical industry as a model to screen for pain-reducing drugs. Finally, the researchers showed that PKC modulates the pain response induced by the chemical known as nerve growth factor. When the factor was injected into normal rats exposed to stimulation, the animals experien......sed to stimuli, such as a protein used to create a model ofasthma in mice. Airways of mice without gamma/delta T cells in their lungsconstricted significantly when exposed to airway stimuli, according to theresearch. In comparison, mice deficient in another type of T cell did not haveairway constriction,...MGH researchers identify angiogenesis inhibitor in gallbladder cancer
...ood vessels (angiogenesis) associated with cancer, model systems in whichtumor cells are grown in an unnatural location - for example, gallbladder cancercells grown under the skin - may produce misleading results. The study's results, appearing in the October issue of Nature Medicine, maysomeday lead to s...Getting your teeth into superplastic forming
...the patient's mouth taken by the dentist. A stone model based on thismould is then duplicated in an "investment" material to produce a completed diewhich is inserted into the superplastic forming press and heated to 900 degreesCelsius over a period of 90 minutes. A disk of titanium is then inserted intot...Scientists grow heart tissue in Bioreactor
...e ATM gene. Once the normal tissue-equivalent model is defined, then these same cells can be manipulated to mimic the stages of breast cancer formation, and the model-related differences evaluated. "We have grown noncancerous human breast cells in the NASA Bioreactor," Richmond...Estrogen may play role in prevention of cataracts
...ne developed cataracts. "This experimental model gives credence to the epidemiological studiesthat ...k ofdeveloping cataracts. "We now have an animal model system that will allow us to determine if thedifferent types of estrogens used in post-menopausal ho...New model suggests that AIDS drugs may not abolish HIV infection
...e HIV from infected individuals, accordingto a new model of the decline in HIV levels during treatment. Ra...y of the drug regimen. One implication of the new model could be a morefavorable interpretation of some treatment outcomes once described as failures,accord...National Cancer Institute awards UNC-CH $5 million for unique prostate cancer studies
...ench, Wilson and Gregory will employ a uniquetumor model known as CWR-22. It consists of human prostate can...bsence ofandrogen," French said. "We are using the model to try to determine whether theandrogen receptor regulates growth even when androgen is absent. Thes......chment, hatred anddelusion. In the Tibetan medical model of treatment for breast cancer, theprescribed therapy consists of herbal compounds designed to treat a woman'sindividual "humors" that are out of balance. Tibetan phytotherapy (herbaltherapy) works by means of a synergistic action of the combination ...Immune system protein may be critical in kidney disorders and other diseases
...kidneys? To addressthis question, Shaw revisited a model concerning CD2AP's potential role in Tcells of the immune system. He developed this model with colleagues Mike L.Dustin, associate professor of pathology, and Paul M. Allen, Ph.D., the Rober...... Francisco General Medical Center have developed a model tostudy at the cellular level how viruses like HIV and Hepatitis B and C evade andco-opt the defense strategies of the cells they invade to cause chronicinfections. In a study reported in the Proceedings of the National Academy of Sciences, agroup l......ithpurification factors approaching 1,000-fold for model protein systems, meaningthat 99.9 percent of all i...In addition, he says, if the results obtained with model systems provesuccessful, "We could potentially reduce the total number of steps required forpurifica...How alcohol may harm your baby's brain
... of survival. West and his colleagues used rats to model alcohol effects on fetal braindevelopment. Although human gestation lasts approximately nine months, comparedto 22 days for a rat, West noted that all mammals pass through the same stagesof brain development despite the different timing of those sta...Yale cancer center to test cervical cancer prevention drug: NCI grant funds research
...e. Animal testingwas possible because of a rabbit model developed by Janet Brandsma. The CancerCenter provided funding to keep the project going, and the result -- at the veryleast -- is a clinical trial."...Federal institutes and the Robert Wood Johnson Foundation create Tobacco Use Research Centers
...bility and use in humans using a shared conceptual model across multiplelevels of analysis; The University of Southern California, Los Angeles Principal Investigator: C. Anderson Johnson, Ph.D. Theme: preventing tobacco use among youth of diverse cultures; Georgetown......nfection." One major limitation of the SIV model is that the outer membrane of SIVis different from...ating a vaccine based on asurface protein, the SIV model has limitations. So the researchers developed aSHIV animal model by combining human and monkey AIDS...