UNC studying new drug against ovarian and endometrial cancers
... women. "This 3rd generation SERM has been modulated to increase its ability tobind to estrogen receptors probably about 10-fold more than what is currentlyavailable," Van Le says. Ovarian cancer is the most lethal gynecological cancer. It accounts for40% of all cancers among women and ranks se...New evidence suggests reconsidering causes and treatments for schizophrenia
... examine what happens when cholinergic activity is modulated in schizophrenic patients. To do this, they chose polysomnograhy or sleep studies. The muscarinic cholinergic system exerts a strong influence over REM -- or dream -- sleep, especially the first dream phase after onset of sleep. Therefore, Tandon...Lawrence Livermore Lab pioneers advanced radiation treatment for cancer
... dose distributions for the most complex intensity modulated radiotherapy plans," said Lynn Verhey, Ph.D., prof... of planning and delivery technology for intensity modulated radiation therapy (IMRT). NOMOS introduced IMRT, which has been described as the most significant b...Lack of trained staff and technical support exposes patients to increased risk of cancer progression
...he new advances include: External beam intensity modulated radiotherapy (IMRT) has produced remarkable technological advances in radiation therapy in the treatment of particular tumours, eg, head and neck, prostate, breast, lung, rectum, and central nervous system. It reduces side effects associated with con...Calcium-dependent potassium channels as target to increase drug delivery to brain tumors
...edars-Sinais Maxine Dunitz Neurosurgical Institute modulated the calcium-dependent potassium channels of blood vessel cells to increase permeability of the blood-brain tumor barrier (BTB). As a result, they were able to selectively deliver drugs directly to the area of brain tumors without increasing delivery ...Exercise has a more powerful impact on the brain than previously thought
...in both animals and humans. "Just how exercise is modulated in these important functions is not clear," says Edgerton, "but new experiments showing enhanced vascularity in areas of the brain associated with motor control in nonhuman primates provides an example of a change in the tissues of the brain." These ...Gender and sex hormones affect the brain's pain response and more, according to new studies
...ms in the human brain and that these responses are modulated by blood levels of sex hormones," says Zubieta. The linking of pain sensitivity and regulation to reproductive hormones--particularly estrogen--makes some "evolutionary" sense, Zubieta says. Women require more flexible, adaptive mechanisms to protec...Elderly experience long-term cognitive decline after surgery
...ry, Monk said. During surgery, inflammation can be modulated by temperature control, use of regional rather than general anesthesia or the use of beta-blockers. After surgery, closer attention should be paid to optimal pain management and infection control, she said....UT Southwestern Moncrief Cancer Center is first in Texas to treat patients with TomoTherapy
...n center and were the first to introduce intensity modulated radiation therapy seven years ago in North Texas, we now offer another first. "This time it's TomoTherapy, whose advantages are substantial and unique." ...Brain activity reflects complexity of responses to other-race faces
...ay trigger an early emotional response that can be modulated by more conscious processing. The current work builds upon a tool for assessing bias developed in 1998 by Banaji and Anthony Greenwald of the University of Washington, which is now available online at http://implicit.harvard.edu . This self-administ......s depends on calcium channels, which, in turn, are modulated by cell calcium. " CaMKII mediates an important regulatory pathway that influences calcium cycling in the cell and modulates many processes involving calcium, including activities of calcium channels" said Rudy. "Having this pathway modeled is a val...