Biological Markers Found That Correlate To Esophageal Cancer Treatment Success
...e found that the 88 patientswith Pgp survived 20.9 months on average, while the 24 patients without Pgp hada...e of 21 months, while those without it survived 47 months on average. The third implicated marker was HER-2/neu, which initiates chemical signalstelling the...Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results
...o grow. Despite a life expectancy of three-to-nine months when enrolled, patients with acomplete or partial response are alive more than 15 months later. "Although only small numbers of patients have been treated so far, theseoutcomes should incre...Sniffing Out The Promise Of Anti-Angiogenesis Therapy
...17 patients, thedisease has not progressed for six months or longer. "All this occurred with very few side effects," says Gill, "which were limitedmostly to mild headaches." IM862-now well into Phase III clinical trials-is among the firstanti-angiogenesis drugs to get to this phase all on its own, says Gill......typically responds tohigh-dose IFNa2b within a few months of administration, we may betterselect patients who are likely to benefit from this therapy and steer thosepatients who are not responding using these parameters to other therapies thatmay provide them a greater benefit," added Dr. Kirkwood. Dr. Kir......efree of acute cellular rejection in the first six months versus 18 percent inthe control group. Similar results are being seen in those patients followedfor more than 18 months. Chronic rejection in lung transplant patients was alsosignificantly less for the bone marrow patients, 4.7 percent in the bone ...Mayo Clinic Study Finds Costs For Cancer Clinical Trials Comparable To Costs For Standard Treatment
...om the date of trial entryuntil either death or 60 months following entry into the trial. Case subjectswere residents of Olmsted County, Minn., who entered Phase II or III cancertreatment trials at Mayo Clinic from 1988 through 1994. Control subjects werepatients who did not enter clinical trials, but who...Impulsive Children More Prone To Injuries
...ert, Ph.D., evaluated 59 children when theywere 33 months old, 46 months old and six years old. The children completed astandard battery of tests designed to measure their "...Two Beta-Blocker Drugs Equal In Treating Heart Failure
...viduals taking either of the beta-blockers for six months felt better, wereable to exercise longer without becoming exhausted, and had a 5 percent increasein the ejection fraction test that measures the heart's pumping ability. Anormal ejection fraction is about 50 percent. "Because the most common heartp...Stress speeds passage from HIV to AIDS, support retards it
...ected gay men and tested theparticipants every six months for disease status (AIDS was determined byCD-4 lymphocyte count below 200 and/or having an AIDS indicator condition),depression, stressful life events, and social support. Thirty-three percentof the men progressed to AIDS, in an average time of 2.8 ...Controversy Over The Effects Of Passive Smoking
...ilar conclusions in the BritishMedical Journal six months earlier (vol 315, p 973). Law notes that if youcompare people who actively smoke just five cigarettes a day with people whosmoke 20 a day, the increased risk is also non-linear (see Graph). The lightersmokers increase their risk of heart disease by 4...... angioplasty of an inert substance (placebo). Six months after angioplasty, among the individuals in the high-risk, unstableangina group who had high troponin T levels and received abciximab, 9.5 percenthad heart attacks or deaths, compared with 23.9 percent of the people in theuntreated (placebo) high-ris...Showing pictures of admired blacks or elderly can lower levels of unconscious prejudice
... conducted on the World Wide Web in the last eight months involving morethan 50,000 Americans, Greenwald and Yale University colleague Mahzarin Banajidemonstrated that 80 percent to 85 percent of white Americans unconsciouslyprefer whites over blacks. The Web version of the IAT also demonstrated hig...New outpatient surgery is helping women with stress incontinence
...at rest). Klutke assessed 38 of these patients two months after their surgery dates. Hefound that 79 percent of them no longer were incontinent, 16 percent had grade Isymptoms, and 5 percent had grade III symptoms. These outcomes are very similarto those with traditional slings. "But the TVT procedure is a ...Immunex Files Supplemental NDA for NOVANTRONE
...mptoms flare up andthen ease or even disappear for months or years. Eventually, the neurologicalfunction of patients who develop secondary progressive MS begins to steadilyworsen as flares become more frequent and severe, and recovery is incomplete. There are currently no approved treatments in the United ...Men at highest risk least likely to comply with post-heart-attack exercise program, UB study finds
...k. Before being enrolled, and at every six months in the three-year trial,participants received a physical examination, performed an exercise test on atreadmill, and answered questions about their lifestyle. Dorn found that men with a higher work capacity, higher peak heart rate,and higher H...Aging alone does not affect brain system related to memory loss
...hers examined both young adult rats (four to seven months old) andold adults (24 to 28 months old). In addition, some rats had brain lesions thathad destroyed some of the neurons in the choliner...Early warning signs of violence often overlooked, study finds
...s with peer harassment to go under-attended to for months oryears." In the study, more than 90 percent of participants incorrectlyidentified the following scenario as a bullying situation: Jackie came home with a ripped shirt, a bruised cheek, and scrapes onher arms. Her mom was both scared ...Early stroke treatment with t-PA has long-lasting benefit, according to NEJM report
...more likely to have minimal or no disability at 12 months than were theplacebo-treated patients?" the group ...gnificantly between the t-PA and placebo groups 12 months afterstroke. Stroke or brain attack occurs when parts of the brain become starvedfor blood. ...Health services and local authorities can work together to help prevent playground injuries
...where changes had been made fell from 53 in the 18 months before changes to 21 in the 18 months after. There was only a small fall from 35 to 28 in control playgrounds. The authors conclude that......survival time has not yet been reached at about 10 months after the last patientwas enrolled. The safety pro...d cell count, 61%) that usually improvedwithin two months post-therapy. Some patients entering the study with severe (grade 3 and4) thrombocytopenia and neut...