Obese lung-transplant recipients at higher risk of death
...ion than normal. The added strain on the lungs and muscles involved in breathing can damage an obese persons ...or chest operation, but their impaired respiratory muscles make it very difficult for them to recover after setbacks such as pneumonia or rejection, complicati...Study could lead to exercise-mimicking drug
... sudden heavy exercise such as weightlifting makes muscles larger while sustained exercise such as long-dista...xercise regularly have more mitochrondria in their muscles than those who are sedentary, Williams said. The scientists produced genetically altered mice that p...Enzyme halts muscle waste in mouse models of most-common childhood muscular dystrophy
...an enzyme called CT GalNAc transferase to skeletal muscles in mice bred to develop DMD. Normally, CT GalNAc ...ation, the house falls apart. Without dystrophin, muscles affected by DMD become damaged and break. Martin discovered the enzyme as he looked for other protei...Muscular dystrophy mouse model yields potential growth factor treatment
...ness and degeneration of the skeletal or voluntary muscles which control movement. The muscles of the heart and some other involuntary muscles are also affected in some forms of MD, and a few...University of Pittsburgh researchers use botox to treat overactive bladder
...omes paralyzed or weakened, but leaves surrounding muscles unaffected, allowing for normal muscle function. Common urologic conditions like neurogenic detrusor hyperreflexia and overactive bladder are caused by involuntary contractions of the detrusor muscle, which controls the bladder. This new therapy hel...While-you-wait implantable heart assist device appears effective
...hours of implantation. Drugs to support the heart muscles contraction became unnecessary. Eight patients underwent physical therapy and improved from severe heart failure (New York Heart Association Class IV) to mild heart failure (NYHA Class I). Although the study protocol required the patients to remain...UF research: For stroke recovery, two therapies better than one
... enhance motor recovery. When administered to the muscles of a paralyzed arm, mild electrical current called electromyogram- or EMG-triggered neuromuscular stimulation is thought to help the brain establish alternate pathways that activate the impaired limb to replace those disrupted by stroke damage and ...A helping hand: Healthy arm helps retrain stroke-impaired arm
..."We wanted to compare how fast they turn on' their muscles before and after rehabilitation," Cauraugh says. Again, the stimulation/bilateral group had faster reaction time 227 milliseconds (ms) vs. 255 ms for the unilateral group. The third test measured sustained muscle contraction by having patients lif...Source of physical performance found in brain
...to the skill itself or does it merely instruct the muscles and joints to improve performance? Dr. James Ashe of the Minneapolis VA Medical Center and colleagues from the University of Minnesota and University of Virginia found that they could train subjects to learn a finger-movement task but prevent them ...Angiogenesis reduces leg pain from clogged arteries
... angina. Walking increases the demand by leg muscles for oxygen, so patients with his condition typically can only walk short distances before the pain forces them to stop. The pain diminishes with rest. Since such pain isthe main symptom limiting the quality of life of these patients, the researcher...High blood pressure treatment also improves heart function
... chronic high blood pressure to changes in the arm muscles from weightlifting: "The heart walls thicken, just as the biceps thicken from lifting weights, resulting in an increased demand for blood supply and energy," he says. The study included 647 hypertensive patients who had enrolled in the Losartan Int...Botox proving successful at preventing headaches
...he toxin that causes botulism, partially paralyzes muscles for about three months. For headache treatment, it is injected into muscles around the eyes and forehead and sometimes the jaw. For patients whose headaches involve the entire ...New pathway for treating hypertension-related kidney failure studied
...ys, it increases blood flow by relaxing the smooth muscles of the blood vessels and also works as an anti-inflammatory agent. In kidney disease, EETs are broken down by an enzyme, soluble epoxide hydrolase, rendering EETs ineffective. Levels of this enzyme somehow increase in hypertension. Dr. Imig is worki...Androgen therapy boosts muscle strength for older men
...lone daily for 12 weeks had significantly stronger muscles in their upper and lower body than men who took a placebo, according to E. Todd Schroeder, Ph.D., postdoctoral fellow in the Department of Medicine at the Keck School of Medicine of USC and lead author of the study. The findings suggest that suppleme...Continuous stitching method reduces pain for women with perineal damage after childbirth
...errupted sutures inserted to re-align the perineal muscles and interrupted transcutaneous stitches inserted to close the skin edges of the wound. 1542 women who had a spontaneous vaginal delivery with associated damage to the perineum were randomly allocated to either the continuous or interrupted suturing ...Muscle stem cells show promise against muscular dystrophy in mouse model
... deliver the missing protein dystrophin to damaged muscles in a mouse muscular dystrophy (MD) model, according to a study supported in part by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The research, carried out by Johnny Huard, Ph.D., and his colleagues at C...New cold treatment developed at the University of Virginia
... through the brain and activates the diaphragm and muscles in the chest. Antihistamine treatment blocks sneezing associated with colds, suggesting that histamine has a role in causing this symptom. Sore throat occurs when pain nerves in the throat are stimulated. Kinin, a potent stimulator of pain nerves, is...Playful therapy garments for children receive patent
...why weights are used -- to provide an awareness of muscles and joints," says Haar. "Working against resistance and the use of weights stimulates muscles and joints. Weights and pressure can also have a calming effect. Most people can relate to the comfo...Preventing misuse of performance-enhancing substances a growing and difficult task
...002). "It is not too hard to imagine the day when muscles can be selectively enlarged or contoured," accordi...consequences of a kinesiologist isolating specific muscles and selectively injecting designer genes into those muscles to maximize their function." The new bo......ility caused by spasticity of the wrist and finger muscles in patients who have had a stroke. This is the fir... toxin type A decreases muscle rigidity in spastic muscles and one small study has shown functional improvement from this therapy. However, use of the therapy ...