'Smart' immune cells kill more cancer
...ode. The marrow T-cells identified not only mature myeloma cells but the primitive cells responsible for the ...marrow T-cells stopped the growth of 86 percent of myeloma stem cell colonies compared to 47 percent for activated t-cells taken from circulating blood. The r...Cancer in patients with hepatitis C
...e risk of both non-Hodgkin's lymphoma and multiple myeloma were significantly higher compared to the general ...ajority of the non-Hodgkin's lymphoma and multiple myeloma patients were estimated to have been infected more than 15 years, which is consistent with the theor...Scientists stalk PPAR-gamma, find novel cancer connection
In laboratory tests on multiple myeloma cells, University of Rochester researchers found t...discovery will lead to a new, targeted therapy for myeloma patients. "To our knowledge, this is the first time anyone has shown that multiple myeloma cells a...Mayo Clinic researchers announce promising next generation treatments for multiple myeloma
... -- can slow the progression of recurrent multiple myeloma is not new. But the studies discussed today show t...d the studies. "However, the treatment of multiple myeloma is like a marathon. In addition to improving the initial therapy to get the disease under control, w...$5 million grant awarded to U.VA health system targets leukemia drug development, creates new jobs
...utions. The concept is that leukemia, lymphoma and myeloma treatments and cures will be discovered most quickly in an environment of collaboration and teamwork." The Bushweller team at the U.Va. Health System is working in collaboration with Dr. D. Gary Gilliland, M.D., Ph.D., at Harvard Medical School,...VELCADE(TM) data confirms long-term survival
... in patients with relapsed and refractory multiple myeloma demonstrated a survival benefit of up to one and a... the first year in patients with relapsed multiple myeloma receiving treatment with VELCADE TM compared to those treated with high-dose dexamethasone. The nov...Researchers find strong familial tendency in rare form of lymphoma
...m's or a related B-cell disorder, such as multiple myeloma or non-Hodgkin's lymphoma. They also found that by a variety of measures age of onset, blood counts, presence of tumor cells in bone marrow, genetic analysis, and other criteria there were no discernible differences between the disease in patients...Study finds Velcade major improvement over standard therapy for relapsed multiple myeloma patients
...ical trial decisively show that recurrent multiple myeloma is more effectively treated with the drug bortezom...with relapsed multiple myeloma." Multiple myeloma is a currently incurable cancer of the bone marrow that causes a plunge in the production of vital r...VELCADE (Bortezomib) receives European marketing authorisation
...er. The novel drug is indicated to treat multiple myeloma patients who have received at least two prior ther... is a completely new approach to treating multiple myeloma that acts on a unique target in cells called the proteasome. Multiple myeloma is the second most c...New discovery may lead to therapy for incurable blood cancer
...al cellular event that occurs in about half of all myeloma cases and identifies an attractive target for ther..., or oncogene, called c-maf and the interaction of myeloma cells with other types of cells within the bone marrow. Using a sophisticated genetic screening tech...New drug may help cancer patients in need of stem cell transplants, Jefferson trial shows
... attempting to determine if patients with multiple myeloma or non-Hodgkin's lymphoma who receive the drug AMD...roll up to 24 cancer patients with either multiple myeloma or non-Hodgkin's lymphoma. Other trial sites include Washington University in St. Louis, the Univers...Northwestern Memorial enrolling participants in two trials on new drug to fight deadly cancer
...ation, for people with multiple myeloma. Multiple myeloma is the second most prevalent cancer of the blood, ... the therapies we currently have to offer multiple myeloma patients come with some pretty unpleasant side effects. Revimid is potent with less toxicity, and it...Mayo Clinic study: Alternative to chemotherapy effective for newly diagnosed multiple myeloma
...tive treatment for patients with relapsed multiple myeloma who had failed all other standard treatments. The ...l treatment of multiple myeloma. Although multiple myeloma accounts for only one percent of all cancers, it is among the most difficult cancers to treat and cu...Fred Hutchinson Research Center awarded $7 million grant
... coordinated efforts to combat leukemia, lymphoma, myeloma and Hodgkin's disease with funding that rivals federal support for blood cancers. Through SCOR grants, teams of researchers representing different disciplines focus on improving the treatment and diagnosis of blood cancers. The research initiative, ...Combined kidney and bone marrow transplantation allows patients to discontinue anti-rejection drugs
...rrow transplantation, which has been used for some myeloma patients. For many years Sykes and her colleagues at MGH -- along with collaborators at BioTransplant Incorporated of Charlestown, Mass. -- have been studying mixed chimerism and its application for both treatment of blood-cell cancers and for induc...Steroid pill prolongs survival in patients with multiple myeloma
...ned their remission and survived longer. Multiple myeloma strikes about 14,000 people in the United States e...vival of patients with multiple myeloma. Multiple myeloma occurs when the body makes an abnormally high number of cancerous plasma cells. When healthy, plasm......hy of undetermined significance (MGUS) to multiple myeloma or related cancers. The significance of this study... MGUS, a condition that is a precursor to multiple myeloma or related cancers. MGUS is present in approximately two percent of Americans age 50 and older and a...New study finds multiple myeloma linked to radiation exposures of nuclear workers
...-and-a-half times more likely to die from multiple myeloma than workers at the same plants whose cumulative e...archers identified 98 workers who died of multiple myeloma and 391 age-matched controls from a combined roster of 115,143 people hired before 1979 at the Hanfo...Copper-lowering drug stabilizes advanced cancer in anti-angiogenesis trial
..., prostate and kidney cancer, sarcoma and multiple myeloma is being planned for this year. A full-scale toxicity test of TM will also begin shortly, though the compound has shown no toxic effects in dozens of Wilson's disease patients who have taken it to remove copper from their bodies. Toxicity data are ...Medical scientists to begin clinical trials of promising cancer therapy
...ases of such blood-borne malignancies as leukemia, myeloma and lymphoma, according to Dr. Robert Z. Orlowski, assistant professor of medicine. "Everybody here is pretty excited about this compound because it's being used experimentally at a few other universities for solid tumors," said Orlowski, a member o...