NIH awards grant to MetaPhore Pharmaceuticals to study novel pain treatments
...lude those with acute, inflammatory and especially neuropathic pain which is generated by causes such as diabetes, AIDS, trauma and cancer chemotherapy. Dr. Salvemini received her Ph.D. under the mentorship of Sir John Vane (winner of the 1982 Nobel Prize in Medicine for his work in the field of pain and inflamm...New discovery may revolutionize treatment for pain related to surgery, illness and injury
...d to deliver the drug gabapentin in a rat model of neuropathic pain to selected dorsal-root ganglia by axonal tra... Clinical trials using axonal transport to treat neuropathic pain will begin in early 2002. In addition to Filler, Dr. Andrew Lever, Dr. Raj Munglani and Dr. G......oking into the different mechanisms that can cause neuropathic pain and is also investigating treatment options u... is also delving into the psychological aspects of neuropathic pain. "Your psychological state can dramatically alter pain processing. Weve found that if somebod...Data reveals Lilly's PKC inhibitor improved symptomatic diabetic peripheral neuropathy
...d instrument to characterize and follow changes in neuropathic symptoms, which reflect alterations in the underlying pathophysiology of diabetic peripheral neuropathy.[iii] To reach this conclusion, they conducted a number of tests to assess the reliability and construct validity of the NTSS-6, as well as corre...Opioids, narcotic analgesics effective in treating post-herpetic neuralgia
...ids can provide a useful alternative treatment for neuropathic pain," said Raja. Yet despite the favorable trends...should be the treatment of first choice in PHN, or neuropathic pain in general," cautions Raja. The study authors recommend more long-term studies of the risks an......e, involving tissue injury as with osteoarthritis; neuropathic or nerve injury, such as diabetic neuropathy; and combination pain, such as cancer or chronic lower back pain. There are also several approaches to treating pain: pharmacotherapy, which uses drugs either alone or in combination; invasive procedures, ...New compound that acts on peripheral receptors may be treatment for some nerve pain
...ientists tested the chemical on mice and rats with neuropathic pain, a complex chronic pain state resulting from ...thstand chronic pain that mirrored human models of neuropathic pain. "Although this is far from being in clinical trials in humans, any new avenue to treat pain is...Antiepileptic drug developed at Hebrew University to undergo phase three clinical trials
...from manic-depression, as well as for treatment of neuropathic pain....Cancer patients find more pain relief when treatment guidelines are followed
... They were also one-third less likely to recognize neuropathic pain. Pain management by non-specialty providers w...pioids, use of short term opioids and treatment of neuropathic pain is infrequent. Matchar and colleagues used their clinical decision and economic analysis model ...Treatment options expand for patients with neuropathic pain
...or treating such pain. The guidelines for treating neuropathic pain appear in the November issue of the Archives ...o your body and to move your hand immediately. But neuropathic pain serves no useful purpose it's the result of damage to nerves that transmit pain signals. And s...New molecule may be basis for drugs that battle overeating and drug dependency
...ts, ranging from overeating and drug dependency to neuropathic pain. Daniele Piomelli, professor of pharmacology at the UC Irvine College of Medicine, and colleagues at the University of Connecticut have created a molecule, AM1172, that regulates the processing of a neurotransmitter called anandamide. In tests o...Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain
...ondition that can result from nerve injury, termed neuropathic pain. Another new animal study supports the development of treatments that target the cannabinoid system for those with obesity. "We found that a compound that blocks activity in the cannabinoid system can significantly reduce food intake in animals...Chronic back pain shrinks 'thinking parts' of the brain, study finds
...g to the leg. The participants were divided into neuropathic -- exhibiting pain because of sciatic nerve damage...s undergo apoptosis -- cell death -- in rats with neuropathic pain. "Given that, by definition, chronic pain is a state of continuous persistent perception with...First-ever safety study of medical cannabis use in Canada launched
...lerosis, arthritis or other kinds of hard-to-treat neuropathic or muscle pain," explains Dr. Mark Ware, principal investigator and pain physician at the McGill University Health Centre (MUHC) Pain Centre. "We are not recruiting cancer patients for this study." "COMPASS participants will be given access to rese...FDA approves Pfizer's Lyrica for the treatment of the two most common forms of neuropathic pain
...ca TM (pregabalin capsules) for the management of neuropathic pain associated with diabetic peripheral neuropath...the first FDA-approved treatment for both of these neuropathic pain states, which are distinctly different from arthritis or musculoskeletal pain. Developed by Pf...Case definition for polyneuropathy developed to standardize research
...e. According to the definition, the combination of neuropathic symptoms, signs, and abnormal electrodiagnostic studies provides the most accurate diagnosis of distal symmetrical polyneuropathy. Electrodiagnostic studies are recommended, since they are objective and validate tests of peripheral nerve function. El...Chronic pain treatments more effective when taken together, new study shows
...oid morphine, patients with two different types of neuropathic pain experienced lower pain intensity than when th... improve quality of life for people suffering from neuropathic pain, a condition that has puzzled health care workers for years because it is often experienced in ...