Journal of Alzheimer's disease to publish ISOA Catalyst Conference
...ly needed. It is expected that, next generation of neuroprotective therapies will stop and/or slow neuronal cell death and will therefore be disease modifying. This timely catalyst conference was sponsored by Forest Laboratories. We are pleased to be working with IOS Press in publishing this important work."...Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain
...ease. "For the first time, our research shows the neuroprotective value of marijuana-like compounds in a well-establ... testing whether the marijuana-like compounds have neuroprotective value when brain cell damage is already present and whether they can prevent the progression of brai...New insights into hormone therapy highlight when estrogen best aids brain
... death, suggesting that progesterone inhibited the neuroprotective action of estrogen in this model. "Together, these data demonstrate that at least some of the neuroprotective actions of estrogen can be inhibited by progesterone," says Pike. "When these results are applied to...Lab studies show two proteins prevented progressive nerve cell loss in Parkinson's disease
...t allow the doctor to regulate the delivery of the neuroprotective proteins as needed." In the laboratory study, the investigators used an adenoviral vector to test the effectiveness of three proteins: Sonic Hedgehog (Shh), a signaling molecule that plays a key role in the development of the brain but is no longer ...How a dietary supplement can protect against Alzheimer's disease
...sed DHA intake should be considered as a potential neuroprotective strategy for AD."...News tips from the Journal of Neuroscience
...lpha. This week, Stein et al. examine the apparent neuroprotective role of sAPP-alpha in mice. Using antibody interference and siRNA knockdown techniques, the authors demonstrate, in hippocampal slices and in vivo, that sAPP-alpha provides the mutant mice with the protective armor of increased TTR and IGF-2 expressi...Study supports new theory for nicotine's protective effect against neurodegenerative disorders
... disease. However, the explanations for nicotine's neuroprotective effects continue to be debated. Now a team of ne... may be additional mechanism underlying nicotine's neuroprotective properties in the brain," said USF neuroscientist R. Douglas Shytle, PhD, lead author of the study. ...Stroke news tips for Friday, Feb. 6, 2004
...sium Efficacy in Stroke) Trial, "the largest acute neuroprotective trial undertaken to date." In this randomized, double-blind, placebo controlled trial, 2,591 patients at 125 centers received either magnesium sulfate or placebo for 24 hours, within 12 hours of stroke onset. In 38 percent of patients, treatment be...Magnesium sulfate to mothers just prior to delivery of preterm babies may improve outcomes
...hat use of prenatal magnesium sulfate may act as a neuroprotective agent for very preterm infants, there have been no... Widespread use of prenatal magnesium sulfate as a neuroprotective agent cannot be recommended solely on the basis of the current study. Although minor adverse effects...Nicotine metabolite shows promise for improving memory, protecting brain cells
..., will use this model for his thesis, studying the neuroprotective potential of cotinine, nicotine and similar drugs in a living disease model. "That is the ultimate test for neuroprotection," Dr. Buccafusco says....Sandia nanolaser may help extend life-spans by rapidly analyzing possible neuroprotectant drugs
...-American company Maas BiolAB, has contributed the neuroprotective agent Cyclosporin A, for which his company holds a patent. According to Keep, Cyclosporin A does "waterproof" the mitochondria, but not well enough. The idea here is to use the Sandia biolaser to establish a benchmark for performance against which to...A cheap and easy way to treat Parkinson disease
...-HB may therefore be considered as a novel form of neuroprotective therapy in the treatment of Parksinson disease....Antidepressant drugs may protect brain from damage due to depression
...nst depression," Sheline explains. "These apparent neuroprotective effects provide a further argument for at least strongly considering remaining on antidepressants." Currently, Sheline's team is looking at whether antidepressant drugs prevent damage to hippocampal neurons or whether they may potentially restore pr...Analysis finds drug improves odds of complete stroke recovery
...d are replicated in a large prospective trial, the neuroprotective drug, citicoline, may revolutionize the treatment ...p stroke damage and improve recovery. However, no neuroprotective drug has been effective. That may be because most studies had too few patients to show positive res...The Lancet Neurology October press release
...romotion of neuronal survival. "The search for new neuroprotective therapies continues and drugs are entering clinical trials. The lessons learnt will hopefully guide these new developments", they conclude. Review articles : The neurology of mitochondrial DNA disease Epilepsy in autism Progressive supranuclear pals...Diet rich in foods with Vitamin E may reduce Alzheimers disease risk
...ious antioxidant supplements that are proposed for neuroprotective purposes, Buckholtz emphasizes. In excessively high doses (above 2,000 International Units daily, or IU/d), for example, vitamin E may be associated with increased risk of bleeding, and patients taking anti-coagulant medications may be especially at ...Study: ER docs can give stroke clot-busters safely, but patients need to get to ER faster
...ion, epidemiology, experimental treatments such as neuroprotective agents and hypothermia, and the basic science of what leads to and happens during a stroke. Signs of stroke: Weakness, numbness or tingling in any part of the body, especially half of the body Difficulty producing speech, getting speech out, or un...Tamoxifen and estrogen have similar effects on the brain
...estrogen that both [tamoxifen and estrogen] may be neuroprotective and may have favorable modulatory effects on aging...bout the value of hormone replacement therapy as a neuroprotective agent. In a few years, we may have reliable information about the neurocognitive effects of estrogen...New study suggests that tamoxifen does not adversely impact brain chemistry
... concluded that both tamoxifen and estrogen may be neuroprotective and may have favorable modulatory effects on aging. Dr. Chlebowski noted, however, that future studies would be necessary to observe the long-term effects of such therapies on cognitive function. Dr. Chlebowski is board certified in internal medicin...New chemistry being developed for delivery of neuroprotective drugs
...h enzymes, 7-nitroindazole, has been shown to have neuroprotective effects in animal models. However, experimentation...ivated by MAO to yield products that will activate neuroprotective mechanisms. We are also testing other derivatives to get a better understanding of the active site i...