New drug shows promise for saving lives from heart failure
...ve action of this substance. But omapatrilat also neutralizes a substance called neutral endopeptidase, resulting in blood vessels relaxing. "Omapatrilat is the first drug in this class and it may be better than the ACE-inhibitor class," says Rouleau. "It may end up replacing ACE inhibitors because it's an ACE...... traveling to the brain from the bloodstream. This neutralizes its psychoactive effect. "The vaccine is very safe and we did not observe any major side effects," said Kosten, professor of psychiatry at Yale School of Medicine. "TA-CD was effective in producing cocaine-specific antibodies, which lasted throughou...Team studies use of Sandia technology to ensure 'farm-to-fork' safety of the nation's food supply
... like: Decontamination formulation that rapidly neutralizes chemicals and biological warfare agents. Rapid Syndrome Validation Project (RSVP) that addresses the identification of naturally occurring or terrorist-caused diseases. Rapid modeling and computing capabilities. Microsensors that can sense chemicals...Molecularly targeted drug slows tumor growth in patients
... a growing tumor. Bevacizumab is an antibody that neutralizes the vascular endothelial growth factor (VEGF) protein, one of many proteins secreted by tumor cells to promote the development of a new network of blood vessels. By binding to VEGF, bevacizumab prevents it from triggering blood vessel growth, thereb...Gout drug shows promise in treating chronic heart failure
...e free radical superoxide is a form of oxygen that neutralizes nitric oxide, a substance created by the endothelium (the inner lining of the arteries) that dilates healthy vessels to accommodate increased demands during exercise. In this randomized, placebo-controlled, double-blind crossover study, researchers...Rensselaer researcher receives $2.1 million grant to develop treatment for anthrax
...bitors. He previously synthesized a substance that neutralizes anthrax toxin, but the compound needs to be tested for its ability to combat anthrax spores. "It is one thing to develop a compound to neutralize anthrax toxin, but it is another thing to create one that humans can take safely," Kane said, adding tha...Novel drug-antidote strategy provides greater control of drug action
...a conformational change, which rapidly and durably neutralizes the activity of the drug." The Duke researchers previously described the discovery and design of this anti-factor IXa aptamer-antidote pair and demonstrated the blood-thinning activity of the drug and the neutralization activity of the antidot......f the vagina in the presence of seminal fluid that neutralizes the vaginal environment. An acidic environment inactivates HIV as well as other pathogens. Each woman in the trial will be placed at random into one of four equally sized groups. One group will use BufferGel before each act of sexual intercourse, one...