Low cost drug helps reduce deaths, repeat heart attacks
...tion," said Dr. Yusuf. "It is more affordable than newer anti-thrombotics, simple to use and of benefit in addition to the broad range of therapies of proven and established value. It is the only treatment for a heart attack that has been convincingly demonstrated to reduce mortality in a single study over...Limitations of current evaluation techniques for the cost-effectiveness of treatments
... Cost-effectiveness is an important issue in PD as newer therapeutic options are costly." Corresponding author Richard Dodel stresses, "Although each of these studies has its distinct value, most currently available models do not explicitly capture the large spectrum of clinically relevant symptoms that p...Drug-eluting stents adopted quickly, with early disparities
... of angioplasties were more likely to be using the newer stents. When the FDA gave its approval, it recommended that drug-eluting stents were to be used initially for fairly straightforward cases of blocked arteries, as was tested in the devices' clinical trials. However, just as is the case with prescribi...Hepatitis C at epidemic levels among young injectors in London
...inge programmes, more risky injecting behaviour in newer injecting drug users, and greater levels of crack injection. There has also been a lack of targeted health promotion campaigns about hepatitis C in recent years....HIV 'higher than expected' among London's drug users
...injecting drug use and injecting risk behaviour in newer drug users than those injecting in the early to mid-1990s. In addition, there may have been increases in the number of injecting drug users over and above any increase in protective measures. The authors argue that current drug policy is failing to p...Chemoprevention backgrounder: Working for a future of cancer chemoprevention
...rious side effects, so researchers are testing the newer SERM, raloxifene, in one of the largest breast can...rson that will help speed up investigation of even newer classes of estrogen blockers and other chemopreventive agents such as COX-2 inhibitors, she says. F...NCI scientists create model that predicts follicular lymphoma survival
... the lowest survival rate should be considered for newer treatments and clinical trials," added Staudt. The fact that the most predictive signatures came from immune cells suggests an important interplay between the host immune system and malignant cells in follicular lymphoma. "One possibility is that th...Success of new treatment halts international blood pressure drug trial
... diuretic, bendroflumethiazide was compared with a newer treatment strategy using the calcium channel block...ecause of cardiovascular benefits in favour of the newer calcium channel blocker plus angiotensin converting enzyme inhibitor treatment when compared with th...Anti-psychotic drugs may be associated with increased risk of diabetes in schizophrenia patients
...round information in the article. "Recently, the newer 'atypical' antipsychotic agents have been linked to several forms of morbidity, including obesity; hyperlipidemia; type 2 diabetes mellitus; and diabetic ketoacidosis [a severe complication of diabetes]." David C. Henderson, M.D., from Massachuset...Mayo Clinic discovery on nature of rheumatoid arthritis lung disease may offer patients therapy
...ains Dr. Turesson: "This is a rationale for trying newer approaches to treating RA lung disease that involve drugs that block T cell action. That might help us make progress against this disease." Studies are ongoing to examine other important subtypes of cells involved in RA lung disease and to discover ...Study shows drugs such as Vioxx and Celebrex were widely over-used long before recent problems
...e the risk of GI bleeds and stomach ulcers. These newer and far more expensive drugs were designed to target only COX-2 and to be used to treat patients with chronic inflammatory disorders such as arthritis. The COX-2 inhibitors are no more effective in relieving pain than aspirin, ibuprofen, or any of th...Vioxx went mostly to patients who didn't need it, Stanford researcher says
...ency among patients and physicians to believe that newer drugs are better than existing medications. "Drugs are approved on the basis of their superiority to placebo, not their superiority to existing drugs," Stafford said. "I think people misunderstand the nature of FDA approval and the criteria used to a...Steroids increase death risk from traumatic head injury
...mend that routine use of steroids be stopped. This newer analysis published by the British-based Cochrane Library draws heavily from a recent study of corticosteroid treatment for brain injury, including coma and concussion, that included 10,008 patients, more than all similar studies combined. The large ...Vaginal hysterectomy leads to better outcomes than abdominal surgery
...ysterectomy with another. "The introduction of the newer techniques of laparoscopic hysterectomy has, we fe... made us all look more critically, not only at the newer approaches, but indeed at all approaches to hysterectomy," Johnson says. According to a 2002 report ...Reviparin effective in reducing risk of death after heart attack
...ath and illness remains high. No antithrombotic or newer antiplatelet drug has been shown to reduce the risk of death after a heart attack. Salim Yusuf, D.Phil., F.R.C.P.C., of Hamilton General Hospital and McMaster University, Ontario, Hamilton, Canada, and colleagues evaluated the effects of reviparin o...Sequential MDCT sufficient for determining possible risk of coronary artery disease
... The study was done using 4-slice MDCT scanners; newer scanners are now being used in many places, Dr. Halliburton said....Calcium and vitamin D most effective for treatment of Crohn's-related bone loss
...mized clinical trials are underway to determine if newer bone-building drugs will have additional beneficial effects on building bone mass in Crohn's patients. The results of those studies will not be available until next year. Until then, researchers suggest vitamin D and calcium supplementation as the ...Over prescribing causing high rates of antibiotic resistance in south and east Europe
...untries the researchers found a growing use of the newer antibiotics (active against a broad spectrum of micro-organisms) and a decline in use of the older antibiotics (active against a narrow spectrum of micro-organisms). The authors believe the data will be useful for assessing public health strategies ...Older women can benefit from chemotherapy to treat breast cancer
...s to offer healthy older patients participation in newer trials, because healthy older patients are likely to derive similar treatment benefits as younger patients."...Common schizophrenia symptoms often overlooked by physicians, according to expert panel
...nization) have existed since the mid-20th century, newer medications introduced in the early 1990s, known a...sychotics were switched to ziprasidone, one of the newer atypical antipsychotics, and showed statistically significant improvement in cognitive symptoms. No...