New study in NEJM suggests levodopa may slow progression of Parkinson's disease
...trolled, double-blind clinical trial involving 361 newly diagnosed Parkinson disease patients. Stanley Fahn...ites in the United States and Canada evaluated 361 newly diagnosed participants with early Parkinson disease. There were four treatment groups: (1) carbidop...New molecular classification of breast cancer predicts response to chemotherapy
...ained tumor tissue biopsies from 82 patients with newly diagnosed breast cancer before they were given a commonly used chemotherapy (Taxol/FAC). Patients with basal-like and erbb2+ subgroups were found to have the highest rates (45 percent each) of a pathological complete response, while only 6 percent of...Updated adjuvant data presented at SABCS show 30 percent reduction in recurrence
...tamoxifen." Pfizer's announcement closely follows newly released American Society of Clinical Oncology (ASCO) recommendations on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone-receptor-positive breast cancer and coincides with the presentation of an update on the...New tipifarnib (R115777) data in AML presented at American Society of Hematology Annual Meeting
... L.L.C. for the treatment of elderly patients with newly diagnosed poor-risk acute myeloid leukemia (AML), were presented at the 46th annual meeting of the American Society of Hematology (ASH). AML is a rapidly progressing form of leukemia, which, in elderly patients, often results in death within a few ...Mayo Clinic researchers announce promising next generation treatments for multiple myeloma
...examethasone as the initial treatment for patients newly diagnosed with multiple myeloma. "These oral reg... the two studies In the first study, 207 patients newly diagnosed with myeloma were treated. Half were randomly assigned to the combination regimen of thali...Long-term benefits for newly diagnosed patients with CML receiving first-line therapy with imatinib
...e, today announced results of a study showing that newly diagnosed patients with a certain form of leukemia...erican Society of Hematology (ASH). In the study, newly diagnosed patients with chronic-phase Philadelphia chromosome-positive (Ph+) chronic myeloid leukemi...New stroke prevention therapy as effective as invasive surgery
...r is inflated, widening the artery. To prevent the newly widened artery from closing up again, a wire mesh stent is put in place to hold the artery open. "Stenting is less invasive than surgery," said Gianluca Piccoli, M.D., an interventional radiologist at the Santa Maria della Misericordia Hospital o...NIAID seeks applicants to lead revamped HIV/AIDS clinical trials networks
...ess in the global search for an AIDS vaccine. This newly designed clinical research structure will now provide us with the opportunity to build on those successes and address future global research challenges." The leadership solicitation, known as a Request for Applications (RFA), is now available for re...New biopsy technique helps assess breast cancer's spread
...he researchers used ultrasound to examine 57 women newly diagnosed with breast cancer. If the lymph nodes appeared abnormal on the ultrasound, the researchers performed a fine needle aspiration, using ultrasound to guide the biopsy. Patients then had breast surgery and either sentinel lymph node sampling o...University of Utah study suggests cellular waste to blame for a form of blinding eye disease
...ear how many cases of RP can be attributed to this newly discovered CA4 gene mutation. "However, we have already gained invaluable lessons from studying four families with this mutation. The next step is to begin working on a pharmaceutical intervention to counteract the effect of the gene mutations," he s...ESA at the world's largest medical exhibition
...ation of tumors to micro-systems for analytics, to newly developed tomographs, telemedicine and laser-technology - a perfect environment for ESA to show to a specialised audience the vast range of possibilities which space research offers to the health sector. Space medicine is not limited to monitoring th...More muscle means better regulation of blood pressure, study finds
...and decreased ability to return to normal. For the newly published study, researchers measured the blood pressure of study participants every 15 minutes throughout a two-hour baseline period, an hour of competitive video games and a two-hour recovery period. They found that while blood pressure increased ...FDA grants accelerated approval of TYSABRI, formerly antegren, for the treatment of MS
... group, 60 percent of patients developed no new or newly enlarging T2 hyperintense lesions compared to 22 p...AVONEX, 67 percent of patients developed no new or newly enlarging T2 hyperintense lesions compared to 40 percent in the AVONEX plus placebo group (p "I beli...Examination of possible conflicts of interest to influence look at suspected adverse drug reactions
...for additional duplicative regulatory oversight of newly marketed drugs; our FDA colleagues can be trusted to do the job, given sufficient resources. However, it is also critical that the nation commit to adequately funding CERTs (Centers for Education and Research in Therapeutics), a Center for Drug Surv...Imaging study finds a structural difference in the brains of cocaine addicts
...ne addiction or changes caused by drug use. Using newly developed imaging techniques to produce extremely detailed structural information, the researchers analyzed data gathered in earlier imaging studies of 27 cocaine addicts who had participated in cocaine infusion studies. For purposes of comparison, t...Chemoprevention backgrounder: Working for a future of cancer chemoprevention
...es as M. D. Anderson's principal investigator on a newly created consortium of six research centers that are working together on cancer prevention. The National Cancer Institute's Division of Cancer Prevention recently devoted $42 million to the group, directing them to work as hard and fast as they can on...Developmental issues among triplet infants
...tigue), and to pay close attention to the infant's newly acquired skills. Because the development of infant cognitive competencies is built upon the mother's sensitive approach and timely introduction of new learning material, we expected, then, that triplets would exhibit poorer cognitive outcomes at 1 ...Panel offers recommendations for monitoring adverse events from dietary supplements
...inistration (FDA) and the product manufacturers. A newly released report may further help consumers, regulators and manufacturers learn more about the safety of dietary supplements. The report, entitled "Recommendations for Adverse Event Monitoring Programs for Dietary Supplements" is the latest scienti...USF neuroscientists awarded $1.1 million NIH grant to improve Alzheimer's vaccine
...ammation can be blocked by an antibody. In the newly funded study, Dr. Tan and Dr. Morgan plan to administer this anti-CD40 ligand antibody to mice genetically engineered to develop symptoms similar to Alzheimer's disease. The mice also will be immunized with an investigational anti-Alzheimer's vaccin...... The study further provided the opportunity to use newly available gene array technology to study AA's molecular mechanisms. In this 5-year study, published in the Journal of Investigative Dermatology, researchers identified a virtually identical mouse model for human adult onset AA and were able to rep...