Coronary stents do not improve long-term survival
DURHAM, N.C. -- While the placement of stents in newly reopened coronary arteries has been shown to reduce the need for repeat angioplasty procedures, researchers from the Duke Clinical Research Institute have found that stents have no impact on mortality over the long term. In the largest such analysis ...Genetic testing can identify ischemic and nonischemic heart failure
... (a type of heart surgery) and biopsy samples from newly diagnosed patients. "Now that we know we can genetically profile heart patients according to ischemic and nonischemic heart disease, our next step is to develop a test that can be used in a clinical setting," said senior study author and cardiologi...NIH recognizes IU as leader in STD research
... biostatistics, clinical and laboratory cores. The newly formed center represents the collaborative strength of infectious diseases, adolescent medicine, biostatistics and microbiology and immunology. The center director is Stanley Spinola, M.D., director of the Division of Infectious Diseases and David H....Researchers discover potential skin cancer prevention target
...cluding lymphomas and solid tumors. Because of its newly discovered role in the initiation and promotion stages of skin cancer, intensive effort should now be focused on researching the proteins activated by STAT3, DiGiovanni said. The researchers became interested in the role of STAT3 when they learned it...Study looks at events that lead to disability among the elderly
... additional cost of medical and long-term care for newly disabled U.S. elderly individuals is estimated to be $26 billion per year." Thomas M. Gill, M.D., and colleagues from Yale University School of Medicine, New Haven, Conn., assessed 754 people aged 70 years or older, who were not disabled (not req...American Thoracic Society journal news tips for November 2004 (first issue)
... These persons were at least 60 years of age, and newly diagnosed with serious illness. Their health problems included 1 of 9 malignancies, stroke, congestive heart failure, hip fracture, or heart attack. Of the total cohort, almost 55 percent used critical care at some time after their diagnosis. Much...NIAID launches program to improve medical tools against emerging infectious diseases
...and influenza. NIAID will make information on each newly identified epitope freely available to scientists ...ism. Almost all of the institutions will evaluate newly discovered epitopes in preclinical or clinical studies, where feasible, for their capacity to elicit...Virco establishes comprehensive set of clinical cutoffs for the vircoTYPE HIV-1 resistance test
...ishes a comprehensive set of clinical cutoffs -- a newly established threshold for optimal selection and evaluation of antiretroviral regimens -- for the virco®TYPE HIV-1 resistance test. These reference values are derived from the largest clinical outcomes database used to generate clinical cutoffs, a...Nerve navigation findings prompt new direction for spinal cord research
...ormation for that kind of puzzle," she says of the newly published work. The researchers are looking for other molecules that also play a role in directing axonal growth. "We have lots of information about how this molecule talks with other molecules," Dr. Xiong says. "We just need to get a s...Supervised treatment interruptions fail to control HIV-1 viremia
...tages of acute HIV infection. HIV-1 viral loads in newly infected patients remained suppressed for a median of six months after therapy had been stopped. However, a follow up paper, published this month in PLoS Medicine by the same research group, shows that the viral load rebounded in eight of the 14 pa...Jefferson scientists find new way to convert adult human stem cells to dopamine neurons
... neural stem cells are grown. They found that the newly differentiated cells didn't merely look like dopamine neurons, but expressed traits of neurons and related cells called astrocytes and oligodendrocytes cells derived from neural stem cells. What's more, the neurons produced tyrosine hydroxylase, an ...... both risk factors for diabetes." Bowden said the newly discovered gene could be a significant contributor to diabetes in Americans. With Josyf C. Mychaleckyj, "we've carried out calculations to try to assess how much of an impact the different forms of this gene have on diabetes in the population. The be...New hope for ALS seen with genetic techniques, growth factors
...hat control muscles. The estimated 5,000 Americans newly diagnosed each year experience progressive muscle weakness that can hinder movement, speech, and even swallowing and breathing. Most cases of the disease are "sporadic"--that is, they occur out of the blue. About 5 percent of cases are inherited, and...Promise of stem cells amplified
...out, they're gone forever, new evidence shows that newly created neurons may provide hope for treating a wide variety of disorders. Embryonic stem cells have been shown to restore movement after paralysis. And with genetic engineering, stem cells can act as sophisticated protein delivery systems. Scientis...Study: Brain battles itself over short-term rewards, long-term goals
...s battling another, it probably is, according to a newly published study. Researchers at four universities found two areas of the brain that appear to compete for control over behavior when a person attempts to balance near-term rewards with long-term goals. The research involved imaging people's brains as...Vioxx: An unequal partnership between safety and efficacy
... data, both for safety and efficacy, provided with newly licensed drugs. For rofecoxib the original safety ...bsequent confidence in the drug misplaced. For all newly licensed drugs, confidence about safety can only be provisional'. 'Pharmaceutical companies also ha...Mechanism found that 'protects' aggressive melanoma from angiogenesis inhibitors
...d melanoma cells expressed different levels of two newly discovered receptors (alpha 5 beta 1 integrin and heparin sulfate proteoglycan 2) for the angiogenesis inhibitor endostatin. Results showed that endothelial cells have significantly higher levels of these receptors. "The differentia...Child health improvement through computer automation
...e most good -- at the time of the office visit. A newly developed computer-based decision support system targeted to medicine's youngest patients utilizes hand-written information acquired from a child's parents within the waiting room, along with preexisting data from the nation's oldest continually oper...DMS offers guidance on educational research
...ld lead to future research endeavors based on this newly obtained data. The primary goal of this examination of the evolution of the DMS educational research environment, according to Nierenberg and Carney, is to offer a resource for other medical institutions. "We hope that it serves as a guide for ......h." For the study, the researchers interviewed 753 newly diagnosed Seattle-area prostate-cancer patients as well as 703 healthy controls who served as a comparison group. Detailed information about tumor aggressiveness (such as tumor grade and disease stage) was obtained through the National Cancer Institu...