Second NIAID SARS vaccine candidate helps mice fend off SARS
...e, giving the microbe a crown-like appearance. The newly described vaccine is based on the spike (S) protein. Because the virus initiates infection by attaching to and entering cells using its S protein, a vaccine based on this protein should closely mimic natural infection, notes senior author, Bernard Mo...Discovery sheds light on how cancer cells grow and divide
...." Significance of the Mayo Clinic Discovery The newly described relationship between Dynamin-2 and the centrosome poses the intriguing possibility that their partnership connects the cell's surface and its interior via signals that coordinate and organize cell division. This is compelling because cancer...Personalized treatment goal of IU breast cancer study funded by $10 million DoD grant
... Programs. "The goal of this project is to utilize newly defined characteristics of both tumors and patients to determine tumor response to chemotherapy in order to allow patients, clinicians and researchers to develop individualized and improved treatment approaches to breast cancer." This grant is one ...Mental health symptoms common at Pentagon after 9/11
...king populations," she says. The survey included a newly designed mental health screening tool produced in part by coauthor Dr. Charles Hoge of the Walter Reed Army Institute of Research....Community screenings uncover hidden diabetes risk
... disease, according to a new report. The number of newly diagnosed and high-risk individuals is in addition to the 11 percent of participants who previously had been diagnosed with diabetes, according to Charles Nordin, M.D., and colleagues of the Jacobi Medical Center, North Central Bronx Hospital and Alb...Office spirometry significantly improves early detection of COPD
...number of "known" COPD cases. In addition, of all newly diagnosed cases of COPD, 42 percent would have rem...ng in general physician practice." The majority of newly diagnosed patients presented with mild to moderate COPD. Of newly diagnosed patients, 45 percent we...Older people recover from disabling events at higher rate than previously thought
...needs to develop ways to help older people who are newly recovered to maintain their independence," Hardy said. The study, "Recovery from Disability Among Community-Dwelling Older Persons," will appear in the April 7, 2004, issue of the Journal of the American Medical Association . "This study offers new ...Annals of Internal Medicine, tip sheet, April 6, 2004
...d Life Expectancy A new study of 521 people with newly diagnosed Alzheimer disease found that the median survival period was 4.2 years for men and 5.7 years for women (Article, p. 501), which is about half as long as people of similar age in the U.S. population would survive. The study found that the sev...Breast cancer patients with BRCA1 or 2 mutations twice as likely to have double mastectomy
...could serve as a valuable decision-making tool for newly diagnosed breast cancer patients at high risk for ...ateral mastectomy are effective treatments for the newly diagnosed breast cancer, these treatments do not protect against the development of a new breast can...Study identifies predictors of Alzheimer's disease longevity
... have the disease. Similarly, 85-year-old men with newly diagnosed AD had a median life expectancy of 3.3 years compared to 4.7 for men of the same age who didn't have AD. Poor scores on the initial tests of memory and cognitive performance predicted shorter survival time after diagnosis. In fact, a five-...Breast cancer patients with BRCA 1/2 mutations twice as likely to choose double mastectomy
...r provided free genetic counseling to 167 patients newly diagnosed with breast cancer, with test results available in about two weeks. Thirty-one women tested positive for BRCA1 or BRCA2 mutations, while tests in the other 136 patients found no mutation or a mutation of unknown significance. Of those who...Higher doses of cancer drug imatinib proven effective and safe
...ival, a positive prospect as the survival time for newly diagnosed CML patients is typically about five years. Another measure of successful treatment is the number of patients with complete molecular response, occurring when the levels of BCR-ABL are so low that they are undetectable using a highly sensit...One form of vitamin E appears beneficial in reducing bladder cancer risk
...earch. In a five-year study, which included 468 newly diagnosed bladder cancer patients and 534 cancer-free controls, the researchers found that high dietary intake of alpha-tocopherol, one form of vitamin E, significantly reduced the risk of developing bladder cancer. But gamma-tocopherol, which i...Monkey virus may hold clue for development of common blood cancer
ORLANDO -- Examination of tumors in patients with newly diagnosed non-Hodgkin's lymphoma found that half o...ma/Myeloma, examined 55 tumors taken from patients newly diagnosed with the disease who had not yet been treated with chemotherapy. After isolating DNA from ...American Thoracic Society Journal news tips for April 2004 (first issue)
...s-sectional studies and a birth cohort. Among 299 newly diagnosed cases of asthma in the Nurses Health Study between 1990 and 1996, 108 used no acetaminophen, 112 used it from 1 to 4 times per month, 41 ingested it 5 to 14 times per month, 16 took the compound 15 to 21 times per month, and 22 used the non...Myosin mutant points to human origins
...s with larger jaw muscles and smaller brains. This newly discovered mutation seems responsible for the development of smaller jaw muscles in humans as compared to non-human primates. These converging lines of evidence suggest the question: Did this genetic mutation lift an evolutionary constraint on brain ...Inhibitors prevent aggresome formation associated with some forms of ALS
...enic mice (an animal model for human ALS) with the newly identified inhibitory compounds might alleviate their ALS symptoms and prolong their life span. Lisa J. Corcoran, Timothy J. Mitchison, and Qing Liu: "A Novel Action of Histone Deacetylase Inhibitors in a Protein Aggresome Disease Model"...Young breast cancer survivors suffer more long-term after effects
...eeds help in the form of the kind of programmes to newly diagnosed patients", said Dr. van de Poll-Franse. "Nowadays all kinds of care programmes exist to deal with the physical and emotional problems associated with a new diagnosis of breast cancer. It is important that we make the same kind of facili...A new hypothesis about Alzheimer's disease
...all the "atheronals." The scientists suggest these newly identified products are critical to the pathogenesis of the disease atherosclerosis because these atheronals were found in atherosclerotic plaques that were surgically removed from patients with atherosclerosis. (Atherosclerosis is a common vascular ...New data on the effect of Atacand(R) on NYHA class in a broad spectrum of heart failure patients
...e CHARM Programme, the number of patients who were newly diagnosed as having Type II diabetes mellitus (6.0% on Atacand compared to 7.4% on placebo; p=0.020) was significantly lower in the group treated with Atacand. Commenting on the presentations, CHARM co-chairman, Professor Karl Swedberg, Gteborg Univ...