Study finds elderly patients achieve seizure freedom on epilepsy therapy
...and one discontinued treatment. Four patients had newly identified epilepsy with Keppra as their first treatment and have been receiving total daily doses of 500 to 1,000 mg for eight to 11 months. The only adverse event in the trial was a seizure in one patient at the lower dose but none to date on 1,00...The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly
... disorder of the young, but the greatest number of newly diagnosed cases each year occurs in the elderly. People over 65 are the fastest-growing group in America to develop the disorder. "Few realize that epilepsy is not just a disorder people are born with - that epilepsy can develop as people age," ...Higher dose of Gleevec leads to increased remission in CML patients
... look at use of high-dose Gleevec in patients with newly diagnosed, early stage CML. Initial dose-escalati... Gleevec, and the other testing the higher dose in newly diagnosed patients. They found that 18 months after treatment, 28 percent of 114 patients treated wi...Three months is too soon to judge a CML patient's response to Gleevec, researchers find
... they examined data from a randomized study of 553 newly diagnosed chronic phase patients comparing Gleevec, also known as imatinib, with traditional combination therapy (interferon and cytosine arabinoside). Scientists first studied whether a CML patient's response to Gleevec is related to a patient's ...Population surveys - A new 'gold standard' for estimating true incidence of HIV/AIDS?
...ic in high-prevalence countries may be improved by newly available information from household surveys. UNAIDS/WHO estimate (2002 figures) that around 42 million people worldwide are infected with HIV-1, with sub-Saharan Africa accounting for just under 30 million infections. Conventional estimates of HIV-1...UCLA studies experimental cancer drug
...UCLA researchers are seeking study volunteers with newly diagnosed prostate cancer who are at high risk for recurrence, meaning they have Gleason scores of 8, 9 or 10 and a PSA level of 20 or greater. Because their cancers are aggressive, these patients generally have a 50 to 70 percent chance of recurrenc...Duke cardiologists offer new view of link between aging, atherosclerosis
... factors at a very early age," Peterson said. "Our newly developing insight into the role of stem cells in the disease process should write new chapters in our understanding of the disease process," he said. "We really don't truly understand repair and rejuvenation, yet they are important factors in determ...Emory, GlaxoSmithKline, NIMH enter public-private partnership to develop new drugs for depression
...velopment by the pharmaceutical company as well as newly discovered candidates. "By joining Emory's longstanding and groundbreaking research programs in depression and mood disorders with the highly successful programs at NIMH and the novel drug development program at GlaxoSmithKline, we hope to betterser...U.S. is poorly prepared for influenza pandemic, St. Jude experts warn
... copies of the virus are made; N proteins help the newly made viruses escape from the cells and spread throughout the body. If either H5N1 or H7N7 had acquired the ability to jump from person to person, the result could have been a pandemic, according to Webster. Moreover, the long time now required to de...UCLA teams with Drew to provide cancer care
...Drew University patients, including studies of the newly targeted therapies that are showing promise in fighting cancer. It also seeks to strengthen Drew University's cancer research and training programs through collaborative research projects and partnerships with UCLA's world-renowned scientists. Additi...Increasing number of physician assistants handle more than 190 million patient visits in 2003
... as PAs at the beginning of 2004, according to the newly released Information Update: Projected Number of People in Clinical Practice as PAs as of January 1, 2004. This estimate more than doubles the number of PAs in clinical practice ten years ago. AAPA estimates there were 23,300 PAs in clinical practice...Leading the way in novel anti-cancer research
...ssel walls retain the characteristics of immature, newly formed dividing cells and appear to depend heavily on a tubulin cytoskeleton to maintain their shape. Vascular targeting agents are designed to disrupt this cytoskeleton, causing the endothelial cells to change shape from flat to round, resulting in...High nuclear grade associated with recurrence of in situ breast lesions
...er Institute . DCIS accounts for about 20% of all newly diagnosed cases of breast cancer in the United States and is initially treated surgically, either by mastectomy (removal of the entire breast) or lumpectomy (removal of the tumor and minimal surrounding tissue). Some women will experience a recurrenc...Age-related outcomes, immune response in patients with brain tumors linked to thymic cells
... "Our findings suggest that levels and function of newly produced recent thymic emigrant CD8+ T cells criti...called gliomas. Twenty-four of these patients were newly diagnosed, while 18 had recurring disease. Seventeen of the patients were enrolled in immunotherapy ...JCI Table of Contents, November 14, 2003
...15induced inflammation and resolve psoriasis. The newly created antibody (146B7) did not compete with IL-15 for binding to its receptor, but interfered with the assembly of the IL-15 receptor alpha beta gamma complex. 146B7 effectively blocked IL-15induced T cell proliferation, and monocyte TNF-alpha rele...Regeneration of insulin-producing islets may lead to diabetes cure
...n, and again donor cells were found throughout the newly developed islets. A separate experiment, however, indicated that islets also could grow from remaining precursor cells in the diabetic mice and resume insulin secretion once the autoimmune process had been halted. Such regrowth from the animal's ow...Heart failure consumes significant health care resources
...our-year costs of $43,385. "It makes sense for the newly diagnosed patients to have higher costs, since the...f the heart to contract strongly enough. In a more newly recognized form of the disorder, known as diastolic heart failure, the heart beats normally but does...UCLA researchers to test experimental pill
...inhibitor as a first-line therapy in patients with newly diagnosed colorectal cancer that has spread to other organs. The study will compare the time it takes for tumors to worsen and overall survival rates among two groups of patients. One group will receive a daily dose of PTK/ZK combined with the chemot...Thanksgiving: A time for healthful eating?
...d not be complete without a steaming cup of joe. A newly identified antioxidant found in coffee is particularly potent at preventing colon cancer, according to a recent study. The research, led by Thomas Hofmann, Ph.D., of the University of Mnster in Germany, was published in the Journal of Agricultural a...Universal bone marrow cell spurs growth of vessels and heart muscle
...alled angiogenic cytokines, also increased or were newly expressed. The same thing occurred with factors important to the development of the heart in utero, called cardiac transcription factors. The number of heart and vessel cells also increased after hBMSC transplantation....