New compounds effective against Alzheimer's disease onset and progression
...s-related enzymes, such as a highly active form of nitric oxide synthase (iNOS). The excessive production o... induced as a result of glial activation generates nitric oxide (NO), which can exist in toxic forms that damage neurons. Therefore, development of new compo...O Christmas tree: Your bark may fight arthritis
...y cells (macrophages) for their ability to produce nitric oxide and prostaglandin E 2 (PGE 2 ), chemicals w...extract (at 50 g/mL concentration level) inhibited nitric oxide production, an excess of which has been linked to arthritis and circulatory problems, by up to...National Academies news: Gulf War and Health
...ned fuels, combustion products, and hydrazines and nitric acid -- components of the propellant used for Scud...personnel may have had contact with hydrazines and nitric acid when they disarmed or disposed of Scud missiles or were downwind of a missile explosion. They ...American Thoracic Society journal news tips for January 2005 (first issue)
... marker of pulmonary cellular dysfunction, exhaled nitric oxide. The investigators studied 31 school-age su...h BPD in the study had significantly lower exhaled nitric oxide levels than did either the healthy control subjects or the preterm children without BPD. For ...Research guides medication choices for young Asthma patients
...ated with allergic inflammation, including exhaled nitric oxide, eosinophils, and serum IgE. Patients who re..., higher levels of the inflammatory marker exhaled nitric oxide, and lower pulmonary function. None of the monitored characteristics was associated with respo...Johns Hopkins scientists receive presidential medals
...tion of novel neurotransmitters, such as the gases nitric oxide and carbon monoxide and D-amino acids such as D-serine, has radically reshaped concepts of neurotransmission. "This honor recognizes Sol as a pioneer in brain sciences research and celebrates his many creative, novel experimental approaches and...Changing chemistry helps explain estrogen threat to the heart
...low. These researchers found that estrogen targets nitric oxide synthase 1, one of three versions of the enzyme that makes the powerful vasodilator, nitric oxide. "What we were finding is that estrogen seems to be what you might call a natural nitroglycer...Mayo Clinic develops first genomic-based test to predict stroke from ruptured brain aneurysm
...low. The Investigation To determine the role of nitric oxide synthase gene variations in ruptured brain aneurysms, the Mayo Clinic team screened the genetic variants of 49 patients who had unruptured brain aneurysms, and compared them with the genetic variants of 58 emergency room patients with ruptured ......phins?" he asks. Dr. Miller says a compound called nitric oxide is known to play a role in the dilation of t...um. "Perhaps mental stress leads to a breakdown in nitric oxide or inhibits a stimulus to produce nitric oxide that results in vasoconstriction," says Dr. Mil......re also taken to measure the levels of circulating nitric oxide, which indicates harmful oxidation associate...than they were among the office workers. Levels of nitric oxide were an average of 30% higher. The levels of 1-OHPG were strongly linked to the levels of 8-OH...